Effects of soman on calcium uptake in microsomes and mitochondria from rabbit aorta.

Daily administration of soman for several days results in several alterations in the vascular neuroeffector system. To determine whether or not soman alters intracellular Ca2+ uptake, the effects of acute exposure to soman or 7-day administration of 5 micrograms kg-1 of soman on the capacity of microsomes and mitochondria from rabbit aortic vascular smooth muscle to take up 45Ca2+ were determined. Acute exposure to soman concentrations of 1-100 microM did not alter significantly (P greater than 0.