Feasibility of collecting long-term patient-reported outcome data in burns patients using a centralised approach.

Background: Collecting patient-reported outcome measures (PROMs) has been a longstanding priority for the Burns Registry of Australia and New Zealand (BRANZ). An earlier pilot of hospital-led PROM collection encountered low participation rates and high loss to follow-up, indicating consideration for an alternative model was warranted.

Aims: To establish the feasibility of implementing centralised long-term PROM collection within the BRANZ.

Twelve-year review of horse-related trauma registry presentations to a regional Australian Emergency Department.

Background: The size, strength, and unpredictability of horses, makes any interaction a potential situation for minor to severe injury. Despite this, horses continue to be popular for work and recreational activities. There have been five recent Australian publications that have examined various aspects of horse-related trauma, but none have been conducted in regional New South Wales (NSW).

An Innate Despair: The Philosophical Limitations of Transhumanism and its Misplaced Hope in Human Enhancement.

This paper sets forth some philosophical foundations of the transhumanist project, drawing on its roots in philosophical positivism and its confidence in the liberating power of technology. Such confidence is interpreted within the sphere of hope, departing from transhumanism's negative presumptions regarding the human condition, and embracing its aspirations for a humanity without limits. However, it is the claim of this paper that such hope is deceptive.

Why might fears and worries persist after a pain education-grounded multimodal intervention for chronic back pain? A qualitative study.

Introduction: The effect of pain education (PE) on pain intensity and function diminishes after a few months in people with chronic low back pain (CLBP). One possible explanation is the return of underlying fears and worries related to the condition.

Objective: To explore topics related to participants' beliefs and feelings that might explain why fears and worries persist after a PE-grounded intervention for CLBP.

Estimating the rates of dementia using administrative data linked to cohort studies.

Background: Current estimates of dementia and Alzheimer's disease incidence and prevalence are required to understand the health needs of the elderly.

Objective: We used two Australia cohort studies, administrative datasets, and data linkage techniques to estimate dementia rates in Australia.

Methods: The study used Australian Longitudinal Study on Women's Health and the Health in Men Cohort Study.

Alcohol consumption in early middle-aged Australian women and access to primary healthcare services: A cross-sectional study.

Background And Objectives: This study describes the prevalence of risky alcohol consumption in Australian women aged 40-45 years. It explores the relationship between demographic factors and access to and usage of primary healthcare services.

Method: Data were obtained from the Australian Longitudinal Study on Women's Health, Survey 8 (1973-78 cohort).

Descriptive qualitative study of breathlessness and its management of Turkish individuals with self-reported heart failure.

Aims: To explore the experiences of individuals with heart failure, with a specific focus on elucidating the full spectrum of symptoms experienced and their subjective descriptions of breathlessness and self-management strategies regarding socio-cultural-behavioural context.

Design: Qualitative descriptive study underpinned by critical realism and situation-specific theory of heart failure self-care.

Setting: Participants from various settings (hospitals and community) in Southeastern Türkiye.

Applications and potential of machine learning augmented chest X-ray interpretation in cardiology.

The chest X-ray (CXR) has a wide range of clinical indications in the field of cardiology, from the assessment of acute pathology to disease surveillance and screening. Despite many technological advancements, CXR interpretation error rates have remained constant for decades. The application of machine learning has the potential to substantially improve clinical workflow efficiency, pathology detection accuracy, error rates and clinical decision making in cardiology.

Nurses' models of spiritual care: Predictors of spiritual care competence.

Objectives: Previous studies have shown that nurses' spiritual care competence is related to characteristics of personal spirituality, training adequacy, and comfort, confidence, and frequency of provision of spiritual care. However, these studies assumed that all participants understood spiritual care in the same way, and used self-ratings of spiritual care competence, which are problematic. Our previous study found that spiritual care was understood in 4 qualitatively different ways that can be arranged in order of competence.

Focusing a Bioethics Lens on the Development and Use of Artificial Intelligence in Medicine and Neurosurgery.

The rapid pace of development and application of digital technology and data science, including artificial intelligence (AI), is transforming our world. In this chapter, we address the question: "Is bioethics relevant to how we should develop, govern, and use AI in healthcare, specifically in neurosurgery?" We recognize that medical decision-making involves uncertainty and is complex, and predicting potential outcomes is difficult. We conclude that the use of AI in neurosurgery is not inherently unethical.

Supporting cancer-related fatigue self-management: A conversation analytic study of nurse counsellor and cancer survivor consultations.

Purpose: Cancer-related fatigue (CRF) is a prevalent and distressing symptom experienced by people affected by cancer. A breakdown of the clinician-patient partnership and suboptimal clinician communication has been identified as a significant barrier to implementing into clinical practice effective self-management strategies for CRF. This study examined the use and impact of communication practices employed by trained cancer nurse counsellors when providing CRF self-management support to cancer survivors.

Therapeutic Applications for Homeopathy in Clinical Practice.

Homeopathy was founded some two hundred years ago by Dr Samuel Christian Hahnemann. Over time, it has grown to be among the most frequently used forms of alternative medicine in Europe and the USA. It is underpinned by the principle of 'like cures like', where highly diluted substances are used for therapeutic purposes, by producing similar symptoms to when the substance is used in healthy people.

Poland, Public Health, Chaplains, Clergy, Mindfulness and Prayer.

This issue commences with a bibliometric analysis of the top 100 most cited articles on religion. It then presents the first of a two-part series relating to research from Poland and progresses to examine the relevance of religion and spirituality to public health. Finally, this issue revisits the long-established and productive discipline of healthcare chaplaincy and various factors relating to parish clergy.

Non-invasive brain stimulation enhances the effect of physiotherapy for balance and mobility impairment in people with Multiple Sclerosis.

Background: Impairment of balance and gait is common in Multiple Sclerosis (MS). Non-invasive Brain Stimulation techniques are promising adjuncts to physical therapy to improve disability.

Objective: To determine if combining transcranial direct current stimulation (tDCS) with conventional exercise therapy enhances balance and mobility in people with multiple sclerosis (PwMS) compared to exercise alone.

17α-hydroxylase/17,20-lyase deficiency (17-OHD): A Meta-analysis of Reported Cases.

Purpose: Homozygous pathogenic variants in the CYP17A1 gene result in defective activity of the steroidogenic enzymes 17α-hydroxylase/17,20-lyase resulting in the clinical syndrome 17-OHD characterised by hypertension, hypokalaemia, and disorders of sexual development. Pathogenic variants of CYP17A1 lead to complete or partial loss of enzymatic activity and clinical presentations of varying severity. This study aimed to examine relationships between CYP17A1 genotype and clinical presentation in a global cohort.

Achieving and sustaining reduction in hospital-acquired complications in an Australian local health service.

Background: Reducing the prevalence of hospital-acquired complications (HACs) is paramount for both patient safety and hospital financial performance because of its impact on patient's recovery and health service delivery by diverting resources away from other core patient care activities. While numerous reports are available in the literature for projects that successfully reduce specific HAC, questions remain about the sustainability of this isolated approach and there may be benefits for more wholistic programmes that aim to align prevention strategies across a hospital. This study describes such a programme that uses evidence and theories in the literature to achieve and sustain a reduction in HACs in an Australian local health service between 2019 and 2022.

Promising biomarker panel to monitor therapeutic efficacy of neoadjuvant chemotherapy in pancreatic cancer patients.

Background: Neoadjuvant chemotherapy (NAC) can provide improved survival outcomes in pancreatic ductal adenocarcinoma (PDAC) patients who respond to treatment, but currently available biomarkers cannot reliably predict NAC response. This study aimed to determine the potential of a previously identified diagnostic and prognostic biomarker panel (i.e.

Imaging flow cytometry reveals LPS-induced changes to intracellular intensity and distribution of α-synuclein in a TLR4-dependent manner in STC-1 cells.

Background: Parkinson's disease is a chronic neurodegenerative disorder, where pathological protein aggregates largely composed of phosphorylated α-synuclein are implicated in disease pathogenesis and progression. Emerging evidence suggests that the interaction between pro-inflammatory microbial factors and the gut epithelium contributes to α-synuclein aggregation in the enteric nervous system. However, the cellular sources and mechanisms for α-synuclein pathology in the gut are still unclear.

Diagnosis and management of hypersensitivity pneumonitis in adults: A position statement from the Thoracic Society of Australia and New Zealand.

Hypersensitivity pneumonitis (HP) is an immune-mediated interstitial lung disease (ILD) relating to specific occupational, environmental or medication exposures. Disease behaviour is influenced by the nature of exposure and the host response, with varying degrees of lung inflammation and fibrosis seen within individuals. The differentiation of HP from other ILDs is important due to distinct causes, pathophysiology, prognosis and management implications.

Primary Arthrodesis or Open Reduction and Internal Fixation for Lisfranc Injuries: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Background: Lisfranc injuries are often managed surgically with primary arthrodesis (PA) or open reduction and internal fixation (ORIF); however, neither approach has been shown to be superior. This systematic review and meta-analysis assessed randomized controlled trials (RCTs) to compare the functional and surgical outcomes of PA and ORIF in the treatment of Lisfranc injuries.

Methods: This study was performed as per the PRISMA protocol.