Do empirically-derived personality subtypes relate to cognitive inflexibility in anorexia nervosa and bulimia nervosa?

Background: Accruing evidence suggests that personality-based approaches to eating disorder classification may offer several advantages over current diagnostic models, with prior research consistently identifying three personality-based groups characterized by either (1) high levels of impulsivity and dysregulation (termed the "undercontrolled" group), (2) high levels of rigidity and avoidance (termed the "overcontrolled" group), or (3) relatively normative levels of personality functioning (termed the "low psychopathology" group). Cognitive inflexibility (i.e.

Fetal Alcohol Spectrum Disorder and Pediatric Neurology: Are We Missing the Connection? A Scoping Review.

Introduction: Pediatric neurology provides care for children with complex developmental disorders with environmental, genetic, metabolic, and teratogenic etiologies. Common neurodevelopmental conditions include attention-deficit hyperactivity disorder (ADHD), and autism spectrum disorder. However, only minimal attention from pediatric neurology journals has been devoted to fetal alcohol spectrum disorder.

Are Patch Testing Reactions Underrecognized in Skin of Color? Evaluating the Frequency of Borderline Reactions by Fitzpatrick Skin Type.

Patch testing reactions can be difficult to interpret in patients with skin of color (higher Fitzpatrick skin types [FSTs]) due to limited erythema or vesiculation. Missed reactions may lead to prolonged allergic contact dermatitis duration and prevent disease clearance in this population. To compare the frequency of borderline patch test reactions in patients with different FSTs (I, II, III, IV, V, VI).

Panthenol Allergic Contact Dermatitis: Sources of Exposure, Reported Cases, and a Call for More Frequent Testing.

Panthenol, a vitamin B5 derivative, is a key precursor in the synthesis of fatty acids that maintain epithelial function. Its ability to aid in moisturization, skin barrier restoration, and wound healing has led to its frequent incorporation into personal care products and pharmaceuticals-many of which are marketed to be hypoallergenic. While contact allergy to panthenol is rather uncommon, rates of positive reactions are on the rise, increasing from 0.

Handgrip Strength has Declined Among Adults, Particularly Males, from Shanghai Since 2000.

Background: Handgrip strength (HGS) is an excellent marker of general strength capacity and health among adults. We aimed to calculate temporal trends in HGS for adults from Shanghai between 2000 and 2020.

Methods: Adults aged 20-59 years from Shanghai, China, were included.

The long-run and intergenerational impact of early exposure to the Great Chinese Famine of 1959-61 on mental health.

We study the effects of early exposure to the Great Chinese Famine on the mental health and subjective well-being of survivors as well as their offspring using data from the 2010 and 2014 waves of the China Family Panel Studies. Our analysis focuses on K6 scores, severe mental illness, and life dissatisfaction. We find that early exposure to the famine has impaired the mental health outcomes of women, but not men (i.

The Fifth Annual Symposium of the Midwest Aging Consortium.

As the healthcare burden caused by an increasingly aging population rapidly rises, a pressing need exists for innovative geroscience research that can elucidate aging mechanisms and precipitate the development of therapeutic interventions to support healthy aging. The Fifth Annual Midwest Aging Consortium Aging Research symposium, held from April 28-30, 2024, was hosted by The Ohio State University in Columbus, Ohio and featured presentations from investigators across the Midwestern United States. This report summarizes the research presented at the symposium, whose topics included cellular senescence and the aging brain, metabolism and metabolic interventions, nutrition, redox mechanisms and biomarkers, and stress mechanisms.

Relationship Between Adverse Childhood Experiences and Resilience: The Indirect Effect of a Sense of Purpose in Life.

Purpose: This study examined the association between adverse childhood experiences (ACEs) and resilience through a sense of purpose in life (SP) among 578 college students, applying resilience theory and positive psychology.

Materials And Methods: Using a cross-sectional, online survey design, data were collected. Most respondents were female (71.

Unlocking the potential of Ni-rich LiNiCoO cathodes: a DFT investigation of performance-limiting factors.

Ni-rich layered oxides, particularly LiNiCoO, have garnered significant attention in the realm of high-capacity cathodes for lithium-ion batteries. Despite their promise, their commercialization is hindered by challenges related to structural instability and defect formation. This study utilizes density functional theory (DFT) to unravel the intricate structural, defect formation, and transport properties of LiNiCoO, thereby providing insights into the performance-limiting factors.

Association between adherence to behavioral intervention and capability well-being among parents of autistic children: a cross-sectional study from China.

Background: High adherence to behavioral interventions among parents of autistic children contribute to improvement in children's behaviors and parental outcomes. However, most of previous studies focused on the effects of intervention adherence on health-related well-being among parents, which is inadequate to capture the multi-dimensional parental burden of caring for autistic children. The aim of this study is to assess the association between parents' adherence to behavioral intervention and their capability well-being.

Intraoperative virtual reality for older patients undergoing total knee arthroplasty: study protocol for a randomized clinical trial.

Background: In an aging surgical patient population, preventing complications such as oversedation has taken increasing priority in perioperative care. Intraoperative use of virtual reality (VR) may decrease sedative requirements. We hypothesize that the use of immersive VR during total knee arthroplasty (TKA) will lead to decreased propofol requirements, improved patient-reported satisfaction, and reduced postoperative opioid requirements compared to active and usual care controls.

Effect of Long-Term Cisplatin Exposure on the Proliferative Potential of Immortalized Renal Progenitor Cells.

Cisplatin (CisPt) is a widely used chemotherapeutic agent. However, its nephrotoxic effects pose significant risks, particularly for the development of acute kidney injury (AKI) and potential progression to chronic kidney disease (CKD). The present study investigates the impact of non-lethal exposure of CisPt to immortalized human renal epithelial precursor TERT cells (HRTPT cells) that co-express PROM1 and CD24, markers characteristic of renal progenitor cells.

Investigation of Real-Time Gaseous Thermal Decomposition Products of Representative Per- and Polyfluoroalkyl Substances (PFAS).

The thermal decomposition of per- and poly fluoroalkyl substances (PFAS) is poorly understood. Here, we present an innovative, comprehensive analytical method to investigate their thermal decomposition, including perfluorocarboxylic acids (PFCAs), alcohol, sulfonates, and GenX (acid dimer), focusing on identifying their breakdown products. In this study, evolved gas analysis-mass spectrometry (EGA-MS) was used for fast real-time screening to determine the significant temperatures to be investigated with the thermal desorption-pyrolysis coupled with gas chromatography-mass spectrometry (TD-Py-GC-MS), which provided detailed information about evolved PFAS and their breakdown products.

Post-surgical acute care utilization and cost of care among cancer survivors with an ostomy: Findings from three large hospital systems in the United States.

Purpose: To describe patterns of 6-month total cost of care and acute care utilization among cancer survivors who received ostomy surgeries in 3 large hospital systems in the United States between 2018 and 2022 and to identify reasons for acute care utilization.

Methods: A retrospective cohort study using electronic medical records and the corresponding hospital revenue data obtained from 3 geographically diverse hospital systems in the United States was performed. 6-month all-cause post-surgical encounters subsequent to respective ostomy surgery dates were included.

An updated and expanded characterization of the biological sciences academic job market.

Introduction: In the biological sciences, many areas of uncertainty exist regarding the factors that contribute to success within the faculty job market. Earlier work from our group reported that beyond certain thresholds, academic and career metrics like the number of publications, fellowships or career transition awards, and years of experience did not separate applicants who received job offers from those who did not. Questions still exist regarding how academic and professional achievements influence job offers and if candidate demographics differentially influence outcomes.

Mapping chaos: Bifurcation patterns and shrimp structures in the Ikeda map.

This study examines the dynamical properties of the Ikeda map, with a focus on bifurcations and chaotic behavior. We investigate how variations in dissipation parameters influence the system, uncovering shrimp-shaped structures that represent intricate transitions between regular and chaotic dynamics. Key findings include the analysis of period-doubling bifurcations and the onset of chaos.

Absolute Agreement Between Subjective Hand Squeeze and Objective Handgrip Strength in Adults.

Kieser, J, Langford, M, Stover, E, Tomkinson, GR, Clark, BC, Cawthon, PM, and McGrath, R. Absolute agreement between subjective hand squeeze and objective handgrip strength in adults. J Strength Cond Res 39(1): 16-23, 2025-Despite handgrip strength (HGS) being considered a convenient muscle strength assessment, HGS lacks routine measurement in sports medicine and healthcare settings because barriers such as time and lack of instrumentation may exist.

Pelvic fractures and thoracolumbar spine injury: A critical overlook in high-impact vehicular trauma management.

Introduction: Pelvic fractures (PF) occur in up to 9 % of trauma cases, primarily from high-impact events, and are associated with increased morbidity and mortality due to frequent concomitant injuries. Thoracolumbar (TL) spinal fractures, particularly at the T10-L2 junction, are also common in high-energy trauma but are less frequently examined in association with PF. Missed TL fractures can lead to serious neurological deficits.

The global and regional burden of diabetic peripheral neuropathy.

Diabetic peripheral neuropathy (DPN) is length-dependent peripheral nerve damage arising as a complication of type 1 or type 2 diabetes in up to 50% of patients. DPN poses a substantial burden on patients, who can experience impaired gait and loss of balance, predisposing them to falls and fractures, and neuropathic pain, which is frequently difficult to treat and reduces quality of life. Advanced DPN can lead to diabetic foot ulcers and non-healing wounds that often necessitate lower-limb amputation.

One step 4× and 12× 3D-ExM enables robust super-resolution microscopy of nanoscale cellular structures.

Super-resolution microscopy has become an indispensable tool across diverse research fields, offering unprecedented insights into biological architectures with nanometer scale resolution. Compared with traditional nanometer-scale imaging methods such as electron microscopy, super-resolution microscopy offers several advantages, including the simultaneous labeling of multiple target biomolecules with high specificity and simpler sample preparation, making it accessible to most researchers. In this study, we introduce two optimized methods of super-resolution imaging: 4-fold and 12-fold 3D-isotropic and preserved Expansion Microscopy (4× and 12× 3D-ExM).

Self-reported health profiles of trauma victims with and without psychiatric histories.

Background: This study examined associations between self-reported trauma exposure and physical health status after control of variance associated with psychiatric disturbance. Physical and mental health diagnoses were examined among participants with and without histories of trauma and post-traumatic stress disorder (PTSD).

Participants And Procedure: College ( = 2,320) and national ( = 663) respondents were surveyed to identify trauma histories defined using the primary DSM-5 diagnostic criterion for PTSD.