236 results match your criteria: "University of North Carolina-Project-China[Affiliation]"

Article Synopsis
  • HIV infection increases the risk of severe COVID-19, prompting the need for vaccination among people living with HIV/AIDS (PLWHA).
  • A study conducted in China surveyed 2,570 PLWHA about their willingness to receive the COVID-19 vaccine, revealing that 57.2% showed willingness.
  • Key factors influencing vaccine willingness included positive attitudes towards vaccination, perceived social support, and awareness of vaccination benefits.
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Background: In the "treat all" era, there are few data on the nature of HIV clinical progression in middle-income countries. The aim of the current study was to prospectively analyze the clinical progression of HIV and its indicators among men in China with acute HIV who have sex with men.

Methods: From 2009-2014 a total of 400 men with acute HIV infection (AHI) were identified among 7,893 men who have sex with men periodic pooled nucleic acid amplification testing, and they were assigned to an AHI prospective cohort in Beijing and Shenyang, China.

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The impact of COVID-19 pandemic on HIV care continuum in Jiangsu, China.

BMC Infect Dis

August 2021

Institute for STI and HIV Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, Gulou District, Nanjing, 21009, Jiangsu, China.

Background: The COVID-19 pandemic seriously threatens general public health services globally. This study aimed to evaluate the impact of the COVID-19 pandemic on the HIV care continuum in Jiangsu province, China.

Methods: Data on newly diagnosed HIV persons for analysis were retrieved from Chinas' web-based Comprehensive Response Information Management System (CRIMS) for HIV/AIDS from 2016 to 2020.

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Background: (CT) is a major cause of infertility and adverse birth outcomes, but its epidemiology among childbearing-age women remains unclear in China. This study investigated the prevalence of CT and associated factors among Chinese women aged 16-44 years who were either (1) pregnant, (2) attending gynecology clinics, or (3) subfertile.

Methods: We conducted a cross-sectional survey and recruited participants from obstetrics, gynecology, and infertility clinics in Guangdong between March and December 2019.

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Need for transgender-specific data from Asia.

Lancet HIV

June 2021

Guangdong Second Provincial General Hospital, Guangzhou 510095, China; University of North Carolina Project-China, Guangzhou, China. Electronic address:

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Background: Social network-based strategies can expand HIV/syphilis self-tests among men who have sex with men (MSM). Sexual health influencers are individuals who are particularly capable of spreading information about HIV and other sexually transmitted infections (STIs) within their social networks. However, it remains unknown whether a sexual health influencer can encourage their peers to self-test for HIV/syphilis.

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Research news in clinical context.

Sex Transm Infect

June 2021

Shields' Medical Writing and Consulting, Philadelphia, Pennsylvania, USA.

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Introduction: The COVID-19 pandemic is impacting HIV care globally, with gaps in HIV treatment expected to increase HIV transmission and HIV-related mortality. We estimated how COVID-19-related disruptions could impact HIV transmission and mortality among men who have sex with men (MSM) in four cities in China, over a one- and five-year time horizon.

Methods: Regional data from China indicated that the number of MSM undergoing facility-based HIV testing reduced by 59% during the COVID-19 pandemic, alongside reductions in ART initiation (34%), numbers of all sexual partners (62%) and consistency of condom use (25%), but initial data indicated no change in viral suppression.

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Simplifying hepatitis C service delivery in resource-constrained settings.

Lancet Gastroenterol Hepatol

May 2021

Department of Global HIV, Hepatitis, and STI Programmes, World Health Organization, Geneva, Switzerland.

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Social innovation in sexual health: a scoping review towards ending the HIV epidemic.

Sex Health

March 2021

Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Bioinformatics, 130 Mason Farm Road, 2nd Floor, Chapel Hill, NC 27599, USA; and University of North Carolina-Project China, No. 2 Lujing Road, Guangzhou, 510095, China; and International Diagnostics Centre, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, 202, LSHTM, 15-17 Tavistock Place, London, WC1E 7HT, UK.

As donor financial support decreases, ending the HIV epidemic in Asia will require novel and sustainable approaches. Social innovation, a community-engaged process that links social change and health improvement, may be useful for helping to end the HIV epidemic in Asia. A scoping review to examine social innovation strategies in sexual health for the Asian region was conducted.

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Globally, the COVID-19 pandemic brings different challenges to the impacted countries. To combat this pandemic, different strategies need to be tailored and implemented in countries with different situations. First, in countries with an ongoing explosion of the outbreak (i.

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Modelling the impact of an HIV testing intervention on HIV transmission among men who have sex with men in China.

HIV Med

July 2021

MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.

Objectives: An intervention developed through participatory crowdsourcing methods increased HIV self-testing among men who have sex with men [MSM; relative risk (RR) = 1.89]. We estimated the long-term impact of this intervention on HIV transmission among MSM in four cities (Guangzhou, Shenzhen, Jinan and Qingdao).

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Background: Human immunodeficiency virus (HIV) self-testing may help improve test uptake among female sex workers. China has implemented many HIV self-testing programs among men who have sex with men, creating an opportunity for promotion among female sex workers. However, there is a limited literature on examining HIV self-testing among female sex workers.

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Estimating the impact of disruptions due to COVID-19 on HIV transmission and control among men who have sex with men in China.

medRxiv

October 2020

MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom.

Introduction The COVID-19 pandemic is impacting HIV care globally, with gaps in HIV treatment expected to increase HIV transmission and HIV-related mortality. We estimated how COVID-19-related disruptions could impact HIV transmission and mortality among men who have sex with men (MSM) in four cities in China. Methods Regional data from China indicated that the number of MSM undergoing facility-based HIV testing reduced by 59% during the COVID-19 pandemic, alongside reductions in ART initiation (34%), numbers of sexual partners (62%) and consistency of condom use (25%).

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Background: Women are under-represented in many mid-career infectious diseases research fellowships, including a TDR fellowship for low- and middle-income country (LMIC) researchers. TDR solicited creative ideas as part of a challenge contest to increase the number of women fellowship applicants. The purpose of this study is to examine themes from submitted ideas and the impact of implementing the top three ideas on the number of women applicants.

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BACKGROUND Coronavirus disease 2019 (COVID-19) is a new infectious disease, and acute respiratory syndrome (ARDS) plays an important role in the process of disease aggravation. The detailed clinical course and risk factors of ARDS have not been well described. MATERIAL AND METHODS We retrospectively investigated the demographic, clinical, and laboratory data of adult confirmed cases of COVID-19 in Beijing Ditan Hospital from Jan 20 to Feb 29, 2020 and compared the differences between ARDS cases and non-ARDS cases.

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Background: The COVID-19 pandemic has affected the world deeply, with more than 14,000,000 people infected and nearly 600,000 deaths. This review aimed to summarize the epidemiologic traits, clinical spectrum, CT results and laboratory findings of the COVID-19 pandemic.

Methods: We scoped for relevant literatures published during 1st December 2019 to 16th July 2020 based on three databases using English and Chinese languages.

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Introduction: Heterosexual infections have contributed to a high proportion of the HIV burden in Asia and Eastern Europe. Human mobility and non-local infections are important features in some cities/countries. An understanding of the determinants of the sustained growth of the heterosexual HIV epidemics would enable the potential impacts of treatment-based interventions to be assessed.

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Modelling the impact of a sex work crackdown on syphilis transmission among female sex workers and their clients in South China.

Sex Transm Infect

February 2021

MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK.

Objective: To estimate the potential effects of an intense sex work crackdown on syphilis transmission in Guangdong Province, China.

Methods: We developed a deterministic compartmental model of syphilis transmission among female sex workers (FSW) and their male clients in Guangdong Province, China. We based model assumptions on census data and scientific literature, and we fitted the model to sentinel surveillance estimates of syphilis prevalence (positive results in both treponemal and non-treponemal tests) among FSW between 2009 and 2013.

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Background: The COVID-19 pandemic has affected the world deeply, with more than 3,000,000 people infected and nearly 200,000 deaths. This review aimed to summarize the epidemiologic traits, clinical spectrum, CT results and laboratory findings of the COVID-19 pandemic.

Methods: We scoped for relevant literatures published during 1 st Dec 2019 to 23 rd Apr 2020 based on four databases using English and Chinese languages.

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Article Synopsis
  • This study compared two methods of delivering HIV self-testing (HIVST) among men who have sex with men (MSM) in China: social media key opinion leaders (SMKOLs) and community-based organizations (CBOs).
  • SMKOLs recruited more participants with a lower rate of HIV positivity and a higher proportion receiving antiretroviral treatment compared to those recruited by CBOs.
  • SMKOLs were also more cost-effective per person tested and per newly identified HIV case, suggesting both methods should be used together to improve HIV testing coverage among MSM in China.
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Crowdsourcing to promote hepatitis C testing and linkage-to-care in China: a randomized controlled trial protocol.

BMC Public Health

July 2020

University of North Carolina Project-China, 1 Global Health Center Office, 2nd Floor of Lao Gan Building, No. 7 Lujing Road, Yuexiu District, Guangzhou City, Guangdong Province, Guangzhou, China.

Background: Hepatitis C virus (HCV) is a growing public health problem with a large disease burden worldwide. In China many people living with HCV are unaware of their hepatitis status and not connected to care and treatment. Crowdsourcing is a technique that invites the public to create health promotion materials and has been found to increase HIV testing uptake, including in China.

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