31 results match your criteria: "University of North Carolina at Greensboro Greensboro[Affiliation]"

Chiral Brønsted Acid Catalyzed Kinetic Resolutions.

Asian J Org Chem

March 2016

K. Petersen, Department of Chemistry and Biochemistry, University of North Carolina at Greensboro Greensboro, Greensboro, NC 27412.

The synthesis of enantioenriched small molecules is an ongoing goal of organic chemists. This focus review explores the use of kinetic resolutions catalyzed by chiral Brønsted acids. Methods include classic kinetic resolutions and dynamic kinetic resolutions.

View Article and Find Full Text PDF

Salivary Stress-Related Responses in Tinnitus: A Preliminary Study in Young Male Subjects with Tinnitus.

Front Neurosci

August 2016

Lab for Clinical and Integrative Neuroscience, School of Behavioral and Brain Sciences, The University of Texas at Dallas Dallas, TX, USA.

Objective: This preliminary study examined if baseline measures of stress-related biomarkers as measured by salivary secretions of specific autonomic [measured by salivary α-amylase (sAA)], endocrine (measured by salivary cortisol), and immune (measured by salivary neopterin) responses are greater in male subjects with tinnitus in response to an induced-stress task.

Method: Twenty male subjects with no significant hearing loss, 10 with tinnitus, and 10 without tinnitus were enrolled in this study.Salivary secretions were collected before and after the induced stress task at four different time intervals.

View Article and Find Full Text PDF
Article Synopsis
  • Hand preference begins to develop in infants within their first two years, with about half showing a consistent preference for using one hand, particularly when acquiring objects.
  • By the end of their second year, most children display a consistent hand preference that affects how they use both hands together for various tasks.
  • These differences in hand usage are linked to variations in brain development and cognitive abilities, with children who establish a clear hand preference early on showing advanced skills in language, object manipulation, and tool use compared to those with a later preference.
View Article and Find Full Text PDF

Quantitative prediction of herb-drug interaction risk remains challenging. A quantitative framework to assess a potential interaction was used to evaluate a mechanism not previously tested in humans. The semipurified milk thistle product, silibinin, was selected as an exemplar herbal product inhibitor of raloxifene intestinal glucuronidation.

View Article and Find Full Text PDF

The dorsal and ventral aspects of the prefrontal cortex (PFC) are the two regions most consistently recruited in divergent thinking tasks. Given that frontal tasks have been shown to be vulnerable to sleep loss, we explored the impact of a single night of sleep deprivation on fluency (i.e.

View Article and Find Full Text PDF

Cognitive psychologists and neuroscientists study most phenomena of attention by measuring subjects' overt responses to discrete environmental stimuli that can be manipulated to test competing theories. The mind wandering experience, however, cannot be locally instigated by cleverly engineered stimuli. Investigators must therefore rely on correlational and observational methods to understand subjects' flow of thought, which is only occasionally and indirectly monitored.

View Article and Find Full Text PDF