Reducing Phosphorus Loss in Short-Cycle Horticultural Production Using Activated Aluminum-Amended Substrates and Modified Fertigation Practices.

To support growth, short-cycle horticultural crops require readily available nutrients. However, this often leads to nutrient leaching. Implementing best management practices in production decisions like incorporating fertilizer retaining amendments to substrates or modifying fertilization programs can mitigate nutrient losses to the environment and associated costs.

Lifestyle strategies to promote proteostasis and reduce the risk of Alzheimer's disease and other proteinopathies.

Unhealthy lifestyle choices, poor diet, and aging can have negative influences on cognition, gradually increasing the risk for mild cognitive impairment (MCI) and the continuum comprising early dementia. Aging is the greatest risk factor for age-related dementias such as Alzheimer's disease, and the aging process is known to be influenced by life events that can positively or negatively affect age-related diseases. Remarkably, life experiences that make the brain vulnerable to dementia, such as seizure episodes, neurotoxin exposures, metabolic disorders, and trauma-inducing events (e.

Ecological and Fitness Correlates of Personality in a Long-lived Terrestrial Turtle.

An individual's behavioral tendencies (i.e., personality or temperament) can influence its interactions with the environment and thus have important ecological and evolutionary consequences for animal populations.

Spatial Ecology, Movements, and Habitat Selection of Clemmys guttata in a Temporally Dynamic Wetland System in North Carolina, USA.

Turtle populations are in decline worldwide, requiring immediate conservation and management actions. For species with broad geographic ranges that cover diverse environmental contexts, region-specific information on declining species could inform more targeted management plans. I examined the ecology of a Spotted Turtle () population in a temporally dynamic wetland system in the Southeastern Plains ecoregion of North Carolina.

Metabolic consequences of sex reversal in two lizard species: a test of the like-genotype and like-phenotype hypotheses.

Vertebrate sex is typically determined genetically, but in many ectotherms sex can be determined by genes (genetic sex determination, GSD), temperature (temperature-dependent sex determination, TSD), or interactions between genes and temperature during development. TSD may involve GSD systems with either male or female heterogamety (XX/XY or ZZ/ZW) where temperature overrides chromosomal sex determination to cause a mismatch between genetic sex and phenotypic sex (sex reversal). In these temperature-sensitive lineages, phylogenetic investigations point to recurrent evolutionary shifts between genotypic and temperature-dependent sex determination.

Random intercept cross-lagged relations among trauma coping self-Efficacy, trauma coping, and PTSD symptoms among rural hurricane survivors.

Background And Objectives: The trajectories of recovery and non-recovery following a disaster are well-documented, but the mechanisms of post-disaster adaptation remain poorly understood. Rooted in social cognitive theory and the transactional model of stress and coping, this study longitudinally investigated the reciprocal relations among coping self-efficacy (CSE), coping behaviors (approach and avoidant), and posttraumatic stress symptoms (PTSS) among highly exposed hurricane survivors.

Design: 261 Hurricane Florence survivors completed measures of hurricane-related CSE, coping behaviors, and hurricane-related PTSS across three timepoints, beginning 5-8.

Overwintering behavior reduces mortality for a terrestrial turtle in forests managed with prescribed fire.

Prescribed fire is an essential management practice in pyrogenic ecosystems, but fire can also be a significant disturbance and source of mortality for both target and non-target species. Seasonal periods of animal inactivity may provide opportunities to design burn plans that minimize negative impacts to species of conservation concern, but few studies have rigorously examined this possibility. Using radiotelemetry, we studied overwintering behavior and interactions with fire in a forest-dwelling terrestrial turtle, the Eastern Box Turtle (), over an eight-year period at two sites that use prescribed fire in forest management.

Evolutionary stability inferred for a free ranging lizard with sex-reversal.

The sex of vertebrates is typically determined genetically, but reptile sex can also be determined by developmental temperature. In some reptiles, temperature interacts with genotype to reverse sex, potentially leading to transitions from a chromosomal to a temperature-dependent sex determining system. Transitions between such systems in nature are accelerated depending on the frequency and fitness of sex-reversed individuals.

Excitotoxic stimulation activates distinct pathogenic and protective expression signatures in the hippocampus.

Excitotoxic events underlying ischaemic and traumatic brain injuries activate degenerative and protective pathways, particularly in the hippocampus. To understand opposing pathways that determine the brain's response to excitotoxicity, we used hippocampal explants, thereby eliminating systemic variables during a precise protocol of excitatory stimulation. N-methyl-d-aspartate (NMDA) was applied for 20 min and total RNA isolated one and 24 h later for neurobiology-specific microarrays.

Received support in the aftermath of Hurricane Florence: reciprocal relations among perceived support, community solidarity, and PTSD.

: The social support deterioration model (SSDM) posits that individuals who do not receive adequate support following a disaster are vulnerable to losses in community solidarity and perceived support, as well as the development of persistent distress. However, limited longitudinal research has evaluated the relations among support and these outcomes among disaster-affected individuals. The current study utilized random intercept cross-lagged panel modeling (RI-CLPM) to examine reciprocal relations among received support, community solidarity, perceived support, and posttraumatic stress disorder (PTSD) symptoms among rural Hurricane Florence survivors (= 261) assessed 5-8 months post-hurricane (T1), and then at two more timepoints at three-month intervals (T2 and T3).

Mammogram Adherence Among Filipino American Women.

Filipino American women experience breast cancer disparities including being diagnosed with breast cancer at a younger age and at a later stage. More Filipino women have breast cancer tumors that are ER-negative or overexpress Her2-neu. These disparities could be effectively minimized with screening mammograms.

Distinct and dementia-related synaptopathy in the hippocampus after military blast exposures.

Explosive shockwaves, and other types of blast exposures, are linked to injuries commonly associated with military service and to an increased risk for the onset of dementia. Neurological complications following a blast injury, including depression, anxiety, and memory problems, often persist even when brain damage is undetectable. Here, hippocampal explants were exposed to the explosive 1,3,5-trinitro-1,3,5-triazinane (RDX) to identify indicators of blast-induced changes within important neuronal circuitries.

County-level correlates of dental service utilization for low income pregnant women. Ecologic study of the North Carolina Medicaid for Pregnant Women (MPW) program.

Background: Dental care utilization for low income pregnant women is met with challenges in the traditional dentist-centered model of care. County-level measures provide insights for policy and roles for stakeholders that extend beyond the dentist-patient relationship. We examined county-level data to generate hypotheses about factors that influence utilization of dental services in North Carolina's Medicaid for Pregnant Women (MPW) program.

Changes in knowledge, attitudes and beliefs in BSN students after SBIRT education and practice in home health.

Background: Substance Use Disorders (SUD) have detrimental effects on US population's health, healthcare system, and economy. Nursing knowledge gaps in SUD justifies need for nursing education in screening for SUD.

Purposes: Purposes include examining differences in: METHOD: This single-group, pretest-posttest study of 488 BSN students who completed education for integrating SBIRT into home assessments.

Impact of spirituality on resilience and coping during the COVID-19 crisis: A mixed-method approach investigating the impact on women.

Spirituality has been known to have a positive correlation to resilience during disasters. This study investigated the impact of spirituality on resilience during our current pandemic. A mixed-method approach was used to analyze correlations between spirituality and resilience of women.

Endosomal-lysosomal dysfunction in metabolic diseases and Alzheimer's disease.

The endosomal-lysosomal pathways and related autophagic processes are responsible for proteostasis, involving complexes between lysosomes and autophagosomes. Lysosomes are a key component of homeostasis, involved in cell signaling, metabolism, and quality control, and they experience functional compromise in metabolic diseases, aging, and neurodegenerative diseases. Many genetic mutations and risk factor genes associated with proteinopathies, as well as with metabolic diseases like diabetes, negatively influence endocytic trafficking and autophagic clearance.

Variation and repeatability of home range in a forest-dwelling terrestrial turtle: implications for prescribed fire in forest management.

Animal movements and use of space are in part determined by interactions between individual attributes such as sex and body size and extrinsic environmental factors such as the seasonal availability, quality and spatial configuration of resource patches in the landscape. Fire is a common and widespread disturbance process that has the potential to affect animal movements through modifications to the environment. Using radiotelemetry, we examined the contribution of these factors to variation in movements and home range over a 5-year period in a forest-dwelling terrestrial turtle, , at fire-maintained and unburned habitats in the southeastern United States.

Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology.

FAAH inhibitors offer safety advantages by augmenting the anandamide levels "on demand" to promote neuroprotective mechanisms without the adverse psychotropic effects usually seen with direct and chronic activation of the CB1 receptor. FAAH is an enzyme implicated in the hydrolysis of the endocannabinoid N-arachidonoylethanolamine (AEA), which is a partial agonist of the CB1 receptor. Herein, we report the discovery of a new series of highly potent and selective carbamate FAAH inhibitors and their evaluation for neuroprotection.

The Role of Lysosomes in a Broad Disease-Modifying Approach Evaluated across Transgenic Mouse Models of Alzheimer's Disease and Parkinson's Disease and Models of Mild Cognitive Impairment.

Many neurodegenerative disorders have lysosomal impediments, and the list of proposed treatments targeting lysosomes is growing. We investigated the role of lysosomes in Alzheimer's disease (AD) and other age-related disorders, as well as in a strategy to compensate for lysosomal disturbances. Comprehensive immunostaining was used to analyze brains from wild-type mice vs.

Early Synaptic Alterations and Selective Adhesion Signaling in Hippocampal Dendritic Zones Following Organophosphate Exposure.

Organophosphates account for many of the world's deadliest poisons. They inhibit acetylcholinesterase causing cholinergic crises that lead to seizures and death, while survivors commonly experience long-term neurological problems. Here, we treated brain explants with the organophosphate compound paraoxon and uncovered a unique mechanism of neurotoxicity.

Addressing health inequalities in diverse, rural communities: An unmet need.

Research on rural health needs to represent the diverse demographics of these regions by carefully considering the distinct characteristics, inequities, and stressors occurring in rural communities. Drawing from our own findings and other empirical investigations examining diverse rural communities, we propose several considerations to guide future endeavors toward more inclusive rural health research. These include population-health assessment tools that consider minority stress and intervention strategies designed to reflect both the environmental and socio-cultural contexts of rural residents.

Responses of a forest-dwelling terrestrial turtle, , to prescribed fire in a Longleaf Pine ecosystem.

Prescribed fire is commonly used as a tool to meet a range of forest management goals. Owing to their limited movement abilities, terrestrial turtles are likely to be at high risk of injury and mortality, and to experience other fitness consequences with population-level implications from fire. Using radiotelemetry, we studied the responses of Eastern Box Turtles, , to prescribed fire management in a sandhills Longleaf Pine forest system over a five-year period and compared our results to a nearby population in an unburned coastal plain location.

The Mediating Effect of Social Controls on Marijuana Use Among Adolescent Bullies, Victims, and Bully-Victims: A Comparison of Various Approaches to Mediation.

This study examines the impact of social control measures (e.g. parental attachment and prosocial peer attachment) on marijuana use among adolescents who were pure bullies, pure victims, and bully-victims.

Race/Ethnic Differences in Nonresident Fathers' Involvement after a Nonmarital Birth.

Objectives: This article examines how the levels of nonresidential father involvement (over child ages 1 to 9) differ by race/ethnicity (comparing White, Black and Hispanic fathers), and then considers how individual and couple characteristics may 'account for' any observed differences.

Method: Data from the Fragile Families and Child Wellbeing Study ( = 2,447) and random effects models were used to examine how nonresidential father involvement (with respect to time, engagement, shared responsibility, and coparenting with mothers) is differentiated by race and ethnicity.

Results: Overall, Black nonresident fathers were significantly more likely to spend time and engage in activities with their children as compared to Hispanic fathers-but not White fathers.