82 results match your criteria: "University of Nigeria Teaching Hospital Enugu[Affiliation]"

Notably, severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and coronavirus disease 2019 (COVID-19) have all had significant negative impact on global health and economy. COVID-19 alone, has resulted to millions of deaths with new cases and mortality still being reported in its various waves. The development and use of vaccines have not stopped the transmission of SARS coronavirus 2 (SARS-CoV-2), the etiological agent of COVID-19, even among vaccinated individuals.

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Key Points: A multinational survey of health care professionals on the kidney health impacts of climate change and the environmental burden of kidney care was conducted. Most participants reported knowledge gaps and high level of concern on these interconnected issues. Only a minority report personal or organizational initiatives in environmentally sustainable kidney care; this did not vary by country income level.

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Background: The rapidity of wound bed preparation is determined in part by the type of dressing agent employed. The extension phase in which the wound is characterized by the presence of sloughs and eschar and microbial invasion could be managed nonsurgically.

Objective: The objective of this study was to compare the rapidity of wound bed preparation using unripe papaya versus honey.

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Introduction: The Lancet Oncology Commission for sub-Saharan Africa (SSA) predicts that cancer deaths will double from 520,158 per year to more than 1 million per year by the year 2040. These striking figures indicate a need to urgently evaluate cancer treatment infrastructure and resources in the region. Studies have found immunotherapy to be effective for the treatment of advanced-stage cancer, which almost 70% of patients in SSA present with.

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International Delphi Consensus Study on disposable single-use endoscopy: A path to clinical adoption.

Dig Liver Dis

February 2024

Department of Gastroenterology, Portsmouth Hospitals University NHS Trust, Portsmouth, UK; School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK.

Background/objective: Increasing infectious rate estimates and low microbiological surveillance affect safety of gastrointestinal endoscopy globally. Single use endoscopes and accessories have been claimed to improve safety, but there is lack of data on their indication and sustainability. We aimed to identify a series of best practice recommendations for the use of single use endoscopes and accessories using a modified Delphi.

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  • Physical inactivity (PIA) is a significant global health risk, contributing to 3.2 million deaths annually, highlighting the need for increased physical activity (PA), especially among healthcare workers (HCW).
  • The study aimed to evaluate the PA levels of HCWs in a major hospital in southeastern Nigeria, utilizing the Global Physical Activity Questionnaire (GPAQ) to gather data on their activity levels and socio-demographic factors.
  • Results showed that 63% of 209 participants achieved the minimum PA required weekly, with factors like age and marital status negatively impacting their activity levels, indicating a need for improved awareness and promotion of physical activity in healthcare settings.
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  • Stroke is a major health issue in Nigeria, making it crucial to understand its patterns and risk factors for better public health strategies.
  • The study focused on stroke patients at a tertiary hospital in Enugu, using data from 350 admitted patients, identifying diabetes, hypertension, and age 65+ as the most prevalent risk factors.
  • Results showed a high prevalence of ischemic strokes (74.9%) compared to hemorrhagic strokes (25.1%), with significant correlations between hypertension and hemorrhagic stroke, especially in younger patients.
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  • Carbapenemase-producing Enterobacteriaceae (CPE) are a serious global public health threat, causing life-threatening infections and highlighting the relationship between antimicrobial resistance (AMR) and environmental factors.
  • Evidence shows that carbapenemase genes are present in the environment, contributing to the spread of resistance and leading to limited treatment options.
  • To prevent the worsening of this public health challenge, effective environmental measures and a 'one health' strategy involving various stakeholders are essential for controlling the spread of resistant genes.
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  • Congenital hypothyroidism is a significant preventable cause of mental retardation, necessitating newborn screening for accurate detection.
  • The study analyzed cord blood samples from 200 term babies in Bauchi, Nigeria, using a cut-off TSH level of >20 µIU/ml for recalls, finding an average TSH level of 3.74 µIU/ml with no samples exceeding the recall threshold.
  • Results indicated that while the mean TSH levels in Bauchi were comparable to a previous multicenter study, there were significant differences when compared to other local studies, suggesting the need for standardized testing and larger multicenter investigations across the country.
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Background: Repetitive seizures are neurological emergencies which may occur in people with epilepsy. Ascertaining the incidence of these episodes of such seizures in the community is wrought with many challenges and few reports exist in sub-Saharan Africa, a region with a high burden of epilepsy. The aim of this study was to describe the caregiver reported frequency of acute recurrent seizures in people with epilepsy attending neurology outpatient clinic in Enugu.

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Background Coronary artery disease was hitherto a rarity in Africa. Acute coronary syndrome (ACS) accounts for coronary artery disease-related morbidity and mortality. Reports on ACS in Africa are few.

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  • Ovarian cancer is more prevalent among Black women in West Africa compared to those in North America, and survival rates are lower for Black women than White women, with factors like histotype and age at diagnosis affecting outcomes.
  • The study analyzed data from Nigerian patients, Caribbean-born Blacks, and US-born Blacks, revealing that Nigerians had a higher percentage of germ cell and sex-cord stromal tumors, whereas Caribbean and US-born blacks had more cases of serous ovarian cancer.
  • Nigerians were diagnosed with epithelial ovarian cancers at a younger age compared to their Caribbean and US counterparts, with all Black women showing earlier diagnosis of germ cell and sex-cord stromal tumors than White women.
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The rapidly rising cancer burden and mortality rate in Africa are in contrast to the increase in cancer survivorship in Europe and North America. Genomic medicine has contributed to the rise in survival and has facilitated precision cancer control. However, there is a shortage of African representation in genomic databases, even for cancers that disproportionately affect Africans.

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  • The study focused on how many people living with HIV in Enugu, Nigeria, disclose their status and what factors influence this decision.
  • A high percentage (80.3%) of participants disclosed their HIV status to someone in their social network, but only 52.4% shared this information with their sexual partners, often delaying disclosure until after diagnosis.
  • Factors that were linked to higher disclosure rates included being female, having formal education, and being 35 years or older.
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  • COVID-19 is caused by the SARS-CoV-2 virus and can result in severe health issues, including respiratory and organ failure, requiring rehabilitation.
  • The African Rehabilitation Network (AFRENET) developed a guidance document to help standardize rehabilitation practices among professionals in Africa due to the rising need for COVID-19 rehabilitation.
  • The report details the process used to create these guidelines, aiming to improve care consistency across the region.
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  • The Nigerian government introduced a free maternal and child health (MCH) program in response to high mortality rates, but it was discontinued with a change in administration, prompting advocacy for political prioritization of MCH.
  • This study utilized qualitative methods, including interviews and document reviews, to analyze how advocacy coalitions form and operate to sustain momentum for MCH policies in Nigeria, using the advocacy coalition framework (ACF) as a guiding tool.
  • Findings revealed key actors and beliefs driving the MCH agenda, highlighting both the effective strategies of advocacy groups and the challenges they face, including external factors impacting coalition formation.
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Introduction: Human Immunodeficiency Virus (HIV) infection remains prevalent co-morbidity, and among fracture patients. Few studies have investigated the role of exercise interventions in preventing bone demineralization in people who have fractures and HIV. If exercise exposed, HIV-infected individuals may experience improved bone health outcomes (BMD), function, quality of life (QoL).

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  • The Nigerian government implemented the Subsidy Reinvestment and Empowerment Programme for Maternal and Child Health (SURE-P/MCH) from 2012 to 2015, aiming to enhance maternal and child health services and later faced a need for sustained advocacy efforts.
  • The study employed a Realist Evaluation design, combining quantitative and qualitative methods, to explore effective advocacy processes and understand how various contextual factors produce desired outcomes in MCH services post-SURE-P.
  • Key stakeholders, including health professionals, civil society organizations, and policymakers, engaged in various advocacy activities, utilizing strategies like alliance building, media involvement, and leveraging influential figures to promote maternal and child health priorities.
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Background: Angular deformities of the lower limbs are commonly encountered deformities in pediatric orthopedic clinics. The values of the tibiofemoral angle undergoes changes as the child grows and these changes are self-limiting. The aim of the study is to establish the normal variation of knee angles of children between 2 and 12 years of age in Enugu metropolis and to establish any correlation between the knee angles and the intermalleolar distances (IMDs).

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  • The study investigates Hepatitis C risk factors in Nigeria, highlighting a lack of clear data on prevalence and how awareness varies by age.
  • The research involved screening 8,790 individuals aged 18-55, identifying 135 positive cases, with injecting drug use, unprotected sex, and sacrification as key risk factors predominantly affecting younger individuals.
  • Findings emphasize the need for early screening and targeted interventions to address these significant risk factors and combat the spread of Hepatitis C.
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  • The study assessed the relationship between overweight and obesity and cancer rates in Nigeria, using data from two cancer registries in Abuja and Enugu.
  • Analyzing 4,336 new cancer cases between 2012 and 2014, they found that 21% of these cases were linked to overweight and obesity, with a higher incidence in women (40.7 per 100,000) than men (8.2 per 100,000).
  • Despite a low overall percentage (1.4%) of cancers attributed to these factors, the research indicates that maintaining a healthy body weight could potentially prevent some cancer cases, especially as future trends may lead to an increased burden.
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Background: In sub-Saharan Africa, cardiovascular disease is becoming a leading cause of death, with high blood pressure as number one risk factor. In Nigeria, access and adherence to hypertension care are poor. A pharmacy-based hypertension care model with remote monitoring by cardiologists through mHealth was piloted in Lagos to increase accessibility to quality care for hypertensive patients.

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  • Early diagnosis and treatment of malaria is crucial, and Nigeria implemented mRDTs for diagnostic testing in 2010; however, their usage among healthcare workers varies across different settings.
  • A cross-sectional study in Zamfara State involved 306 healthcare workers and employed both questionnaires and observational checklists to assess factors influencing mRDT utilization.
  • Results showed that 64.7% of respondents had good knowledge of mRDT, 61.1% of facilities had mRDT available, and multiple factors, including knowledge, trust in results, training, and cost-free access, were significant predictors of mRDT use among healthcare workers.
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  • Access to quality hypertension care in sub-Saharan Africa is limited, but a pilot program in Lagos, Nigeria utilized mobile health technology to connect community pharmacists with cardiologists for remote patient monitoring and hypertension management.
  • The pilot involved 336 patients over 6-8 months, focusing on retention in care, blood pressure changes, and satisfaction levels among patients and healthcare providers.
  • Results showed improved blood pressure outcomes with a 9.9 mmHg decrease in mean systolic blood pressure and increased patient satisfaction, despite some challenges with data reporting and the mHealth application’s usability.
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  • About one-third of Lagos' population has hypertension, with low treatment coverage, prompting a decentralized pharmacy-based care model to be piloted.
  • The study examines recruitment strategies for the program, focusing on community screenings, as well as referrals from hospitals and pharmacies.
  • Results showed that pharmacies were the most effective recruitment source, while community screenings identified many with elevated blood pressure, though not all enrolled in the program.
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