6,608 results match your criteria: "University of Nigeria|[Affiliation]"

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  • * An analysis of over 1 million PE patients from 2016-2021 showed that 12.4% had AF, with those patients displaying significantly higher inpatient mortality (6.05% vs 2.75%) and increased complications like cardiac arrest and respiratory failure.
  • * The presence of AF also led to longer hospital stays (5.66 days vs 4.18 days) and higher hospital costs ($65,235 vs $50,118), indicating a serious negative effect on
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  • * Although chemotherapy is the standard treatment for cervical cancer in Sub-Saharan Africa, it has not delivered the expected survival rates, especially for patients diagnosed with advanced stages of the disease.
  • * Immune checkpoint inhibitors have shown promise in improving survival for advanced cervical cancer and are included in treatment guidelines in high-income countries, but many African nations face challenges in accessing and utilizing these therapies effectively.
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Objective: The study aimed to assess the equity of access to free maternal and child health services among reproductive-age women in Delta State, Nigeria.

Design: the study adopted a descriptive cross-sectional survey design.

Participants: The population for the study were 368 women of reproductive age (15-49 years) who had given birth between April 2015 and December 2015 in two randomly selected senatorial districts of Delta State.

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  • The haemolytic uraemic syndromes (HUS) include various conditions, with some linked to complement activation (CaHUS).
  • The 2023 International Society of Nephrology HUS Forum featured experts discussing the latest knowledge, uncertainties, and proposed solutions in diagnosing and managing HUS.
  • Key areas needing research include naming conventions, complement testing, identifying biomarkers, genetic factors for aHUS, treatment strategies for C5 inhibitors, and improving access to care for patients.
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Prevalence and neighbourhood determinants of early sexual debut and multiple sexual partnerships among young people in Rwanda, Ghana and South Africa.

Afr J AIDS Res

October 2024

Demography and Population Studies Programme, Schools of Public Health and Social Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Article Synopsis
  • The study examines the link between neighborhood characteristics and risky sexual behaviors (RSB) among youth in Rwanda, Ghana, and South Africa, finding a significant prevalence of RSB with varying rates across the countries.
  • It utilizes data from the most recent Demographic and Health Surveys (2014-2016), highlighting that male youth aged 20-24 are particularly at risk for multiple sexual partnerships.
  • The results suggest that community education impacts sexual behavior differently across countries and emphasize the need for targeted policy interventions to mitigate RSB and improve overall community health in Africa.
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The Low-Income and Middle-Income Countries' Perspective on Global Neurosurgery Collaborations.

Neurosurgery

October 2024

Global and Humanitarian Neurosurgery Committee, European Association of Neurosurgical Societies (EANS), Brussels, Belgium.

Background And Objectives: Access to neurosurgical care is limited in low-income and middle-income countries (LMICs) and in marginalized communities in high-income countries (HICs). International partnerships represent one possible means of addressing this issue. Insights from surgeons in HICs have been explored, but data from LMICs' counterparts are scarce.

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Re-emergence of vaccine-derived polio in the demographic Republic of Congo: Causes and consequences.

New Microbes New Infect

December 2024

Department of Research, The Medical Research Circle (MedReC), Goma, Democratic Republic of the Congo.

Poliovirus is a deadly disease that needs to be eradicated in the world. Recently, issues with circulating vaccine-derived polioviruses (cVDPVs) in the Democratic Republic of the Congo (DRC) have been raised in the country. This article aims to determine the increase in Type 1 cVDPV1 and Type 2 cVDPV2 in the DRC.

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Aim Cardiothoracic surgery has the potential to improve care in resource-deprived countries like Nigeria. This study analyzes the barriers to training in cardiothoracic surgery and gaps in the existing curriculum from a cardiothoracic surgery trainee perspective. Methods An online nationwide mixed-method cross-sectional survey was conducted.

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Heavy metal environmental pollution is rapidly increasing due to the increase in industrialization and urbanization. Industrial processes, such as paint production, mining, and raw materials producing industries release effluents rich in heavy metals, like Pb, Cd, Cu, and Cr. These heavy metals are dangerous because they persist in nature, are non-biodegradable and they have high tendency to accumulate in the environment and in living organisms who are exposed to them.

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  • Rubella is a major public health issue in developing countries, especially for preventing congenital rubella, and this study focused on children 10 and under in Jos, Nigeria, from May to September 2016.
  • Researchers used a multistage sampling method to recruit unvaccinated children from schools, testing for rubella antibodies with the ELISA method and analyzing data using R software.
  • Among 405 participants, 82.96% tested positive for rubella IgG, while only 2.22% had IgM, with significant links found between higher seropositivity and factors like being older than 5 years and lacking Western education, indicating a need for a better vaccination program.
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Bioinformatic identification of monkeypox virus phylogenetic gene trees that are representative of its whole-genome phylogenetic tree.

Virus Genes

December 2024

Department of Natural and Environmental Sciences, Biomedical Science Concentration, American University of Nigeria, 98 Lamido Zubairu Way, PMB 2250, Yola, Adamawa State, Nigeria.

Phylogenetic analysis based on whole-genome sequences is the gold standard for monkeypox virus (MPXV) phylogeny. However, genomic epidemiology capability and capacity are lacking or limited in resource poor countries of sub-Saharan Africa. Therefore, these make real-time genome surveillance of MPXV virtually impossible.

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Perfluoroalkyl substances (PFAS) and their distribution in aquatic environments have been studied extensively, but more information is needed to link these occurrences to their physicochemical characteristics. Understanding how these parameters influence PFAS can help predict their fate, mobility, and occurrences in water. This study reviewed the influence of physicochemical parameters on the occurrences of PFAS in aquatic environment using the relevant keywords to retrieve articles from databases spanning mostly between 2017 and 2024.

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Climate and conflict-induced child nutrition crisis in Sub-Saharan Africa.

Confl Health

October 2024

Department of Research and Development, Healthy Africans Platform, Ibadan, Nigeria.

This commentary explores the intersection between climate, conflict, and child nutrition, highlighting the severe child nutrition crisis in Sub-Saharan Africa exacerbated by climate change and ongoing conflicts. Shifting climate patterns disrupt agricultural productivity and food security, while persistent conflicts displace populations and destroy infrastructure, significantly increasing food insecurity and malnutrition among children. Recent UNICEF data indicates that 1 in 4 children globally live in severe food poverty, with those affected up to 50% more likely to suffer from life-threatening malnutrition.

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Mental health has come into the front burner of development challenges amid declining socio-economic outcomes, especially in developing countries. Insecurity, conflicts and extremely threatening events, which trigger mental disorders, are common in South-East Nigeria, with many military operations, unknown gunmen attacks and kidnapping leading to the cold-blood assassination and kidnap of dear ones. The study aimed to analyze the demographic, socio-economic and clinical variables for mental illness in South-East Nigeria.

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The Evolving Role of Palliative Care in Older People with Glioblastoma.

World Neurosurg

December 2024

Department of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom; Office for Research, Innovation and Extension Services, Southern Leyte State University, Sogod, Southern Leyte, Philippines; Center for University Research, University of Makati, Makati City, Philippines.

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Revolution in malaria detection: unveiling current breakthroughs and tomorrow's possibilities in biomarker innovation.

Ann Med Surg (Lond)

October 2024

Department of Haematology and Blood Transfusion Science, Faculty of Medical Laboratory Science, Federal University Otuoke, Bayelsa State, Nigeria.

Article Synopsis
  • Scientists are finding better ways to diagnose malaria by using new tools called biomarkers, which can help find the disease faster and more accurately than old methods like blood tests.
  • These new detection methods are less invasive, meaning they're easier for patients because they can use samples from blood, saliva, or even breath instead of just needles.
  • Future technology may include smartphone apps and wearable devices that help monitor malaria in real-time, making it easier for people in poor areas to get tested and treated.
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Background: Orofacial neoplasms in children and young adults may differ significantly from those observed in adults. Our aim was to describe the epidemiological characteristics of histologically diagnosed orofacial neoplasms among children and young adults in Nigeria.

Methods: This was a multicenter cross-sectional study across geopolitical zones in Nigeria.

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The ageing population of the culturally and linguistically diverse (CALD) population is increasing in Australia. This is because the number of early migrants in Australia is ageing, coupled with increasing family reunification. This scoping review aimed to describe the nature and extent of research on the barriers to aged care services for CALD older adults in Australia using Penchansky and Thomas's Access to Care Framework of five A's dimensions: availability, accessibility, accommodation, affordability, and acceptability.

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Background: Haemorrhage is a leading cause of maternal mortality. The prophylactic use of tranexamic acid during vaginal delivery or caesarean section has the potential to reduce blood loss and postpartum anaemia.

Objective: To determine the effectiveness and safety of tranexamic acid in reducing blood loss during and within twenty-four hours after a caesarean section.

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The Prevalence and Predictors of Burnout Among Resident Doctors in Enugu State, South East Nigeria: A Mixed Method Study.

Niger J Clin Pract

September 2024

Department of Pharmacology and Therapeutics, College of Medicine, University of Nigeria, Enugu Campus, Nigeria.

Article Synopsis
  • * Findings showed that 84.3% of the 420 doctors surveyed experienced burnout, influenced by factors like gender, length of training, and long working hours.
  • * The research calls for interventions to address burnout, improve work conditions, and retain healthcare professionals in Nigeria.
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Incidentalomas in Chest Radiograph of Apparently Healthy Individuals Presenting for Pre-Employment Medical Examination in Enugu State, Nigeria.

Niger J Clin Pract

September 2024

Department of Paediatrics, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Ituku-Ozalla, Enugu, Nigeria.

Background: A chest radiograph is the most commonly requested and performed imaging for diagnosis and screening including medical examination.

Aim: The study aimed to determine the prevalence and pattern of incidentalomas in radiographs of cases presenting for pre-employment medical examination.

Methods: This was a retrospective review of chest radiographs conducted for patients presenting for pre-employment medical examination from January to December 2022.

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Complications and long-term impact of early life pneumonia.

Pediatr Pulmonol

September 2024

Department of Paediatrics, College of Medicine, University of Nigeria, Enugu, Nigeria.

Pneumonia is an infection affecting the lower airway, where the air sacs are filled with mucus and pus; and typically presents with cough, fever, and fast breathing. Pneumonia is estimated to be the leading cause of mortality in children under five worldwide with 120 million episodes result in 1 million deaths globally. The Low-Income and Middle-Income Countries (LMICs) are more affected.

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Recurrent wheezing and asthma-Epidemiology and environmental determinants.

Pediatr Pulmonol

September 2024

Department of Paediatrics, College of Medicine, University of Nigeria, Enugu, Nigeria.

Wheeze is the musical continuous sound produced by oscillations in any critically narrowed airways, and heard mostly on expiration. It is common in preschool age, about half of all children will experience an episode of wheezing by their sixth birthday. Asthma is usually characterized by cough, wheeze, chest tightness and fast breathing.

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