Antiepileptogenic and Neuroprotective Effects of on Pilocarpine Model of Epilepsy.

In this study, we investigated antiepileptogenic and neuroprotective effects of the aqueous extract of roots (PDR) using and experimental models. In studies, status epilepticus caused by pilocarpine injection triggers epileptogenesis which evolves during about 1-2 weeks. After 2 h of status epilepticus, mice were treated during the epileptogenesis period for 7 days with sodium valproate and vitamin C (standards which demonstrated to alter epileptogenesis), or .