1 results match your criteria: "University of Newcastle upon Tyne and Institute for Molecular Medicine[Affiliation]"
Therapeutic approach to the management of HER2-positive breast cancer metastatic to the brain.
Cancer Lett
March 2015
School of Electrical and Electronic Engineering, University of Newcastle upon Tyne and Institute for Molecular Medicine, Huntington Beach, CA, UK. Electronic address:
HER2 positive breast cancers have been shown to have a greater propensity to metastasise to the brain. This may be due to several reasons, including the creation of a "sanctuary-site" for tumour in the brain following trastuzumab therapy. Elucidating the mechanism of this phenomenon may aid the prevention or intervention and treatment of such metastases, but research is limited by the deficiency and diminished access of CNS tissue.
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