3 results match your criteria: "University of New Mexico MSC 10 5550[Affiliation]"
Optimal hepatitis C treatment adherence patterns and sustained virologic response among people who inject drugs: The HERO study.
J Hepatol
May 2024
School of Health Research, Clemson University, Clemson, SC 29605, USA; Department of Medicine, University of South Carolina School of Medicine, 876 W Faris Rd, Greenville, SC 29605, USA; Department of Medicine, Prisma Health, Greenville, SC 29605, USA. Electronic address:
Article Synopsis
- Direct-acting antivirals (DAAs) are very effective for treating hepatitis C virus (HCV) in people who inject drugs (PWID), but adherence to the treatment can vary. This study explored adherence patterns and their correlation with sustained virologic response (SVR) rates.
- Using electronic blister packs, researchers tracked adherence in 496 PWID participants over 12 weeks, finding an overall SVR rate of 92.7% and highlighting that higher adherence was linked to better SVR outcomes.
- The study concluded that significant SVR rates can occur even with some missed doses, emphasizing the importance of reducing consecutive missed days and avoiding early treatment discontinuation to improve treatment success.
Self-reported and measured adherence to hepatitis C direct-acting antiviral therapy and sustained virologic response among people who inject drugs: The HERO study.
Int J Drug Policy
January 2024
School of Health Research, Clemson University, Clemson, SC, USA; Department of Medicine, University of South Carolina School of Medicine, 876W Faris Rd, Greenville, SC 29605, USA; Department of Medicine, Prisma Health, Greenville, SC, USA. Electronic address:
Background: Objective adherence measures, such as electronic blister pack (BP), for direct-acting antivirals (DAAs) for hepatitis C virus (HCV) treatment have high accuracy, but their use is limited in real practice settings. We examined the association of self-reported adherence using a visual analogue scale (VAS) with objective BP adherence and sustained virologic response (SVR) among people who inject drugs.
Methods: We conducted secondary analyses using a subset of participants (N = 493) from the per-protocol sample of the HERO study, a pragmatic randomized trial of HCV treatment interventions that used both VAS and BP to measure adherence to a 12-week sofosbuvir/velpatasvir DAA regimen.
Prevalence of marijuana use in pregnant women with concurrent opioid use disorder or alcohol use in pregnancy.
Addict Sci Clin Pract
January 2022
Division of Epidemiology, Biostatistics and Preventive Medicine, Department of Internal Medicine, School of Medicine, University of New Mexico MSC 10 5550, Albuquerque, NM, 87131, USA.
Background: A quarter of pregnant women use alcohol, 6.5/1000 deliveries are affected by opioid use disorder (OUD), and the prevalence of cannabis use in pregnant women is increasing. However, marijuana co-exposure in polysubstance-using women is not well described.
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