17,239 results match your criteria: "University of Nevada[Affiliation]"

Integrating science education with social justice is vital for preparing students to critically address significant societal issues like climate change and pandemics. This study examines the effectiveness of socioscientific system modeling as a tool within Justice-Centered Science Pedagogy (JCSP) to enhance middle school students' understanding of social justice science issues. It focuses on how system modeling can scaffold students' reasoning about complex social systems, informed by their lived experiences, cultural backgrounds, and social identities.

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A 32-Year-Old Male with Corneal Hydrops.

Clin Pract Cases Emerg Med

November 2024

University of Nevada, Las Vegas, Kirk Kerkorian School of Medicine, Las Vegas, Nevada.

Case Presentation: A 32-year-old male with a history of left eye keratoconus presented to the emergency department with left eye pain and blurry vision for two days. Out of concern for corneal hydrops, ophthalmology was consulted, and the diagnosis was confirmed. Per ophthalmology recommendations, the patient was started on hypertonic saline and prednisolone eye drops and referred to a corneal specialist.

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T. Howard Somervell: War Surgeon, Everest Pioneer, and Medical Missionary.

Wilderness Environ Med

December 2024

Independent Researcher, Bristol, UK.

A full century has passed since George Leigh-Mallory and Andrew (Sandy) Irvine disappeared on the upper reaches of Mount Everest in June 1924. Theodore Howard Somervell (April 16, 1890-January 23, 1975), mountaineer, surgeon, and medical missionary, also was a key player in the 1924 expedition-as well as the 1922 Everest expedition where he was a member of the first ever team of climbers to break the 8000-m barrier. More commonly known as Howard or T.

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The potentially devastating effects of climate change have raised awareness of the need to understand how the biology of wild animals is influenced by extreme-weather events. We investigate how a wild arctic-breeding bird, the Lapland longspur (Calcarius lapponicus), responds to different environmental perturbations and its coping strategies. We explore the transcriptomic response to environmental adversity during the transition from arrival at the breeding grounds to incubation on the Arctic tundra.

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Hydration dynamics and solvent viscosity play critical roles in the structure and function of biomolecules. An overwhelming body of evidence suggests that protein and membrane fluctuations are closely linked to solvent fluctuations. While extensive research exists on the use of vibrational probes to detect local interactions and solvent dynamics, fewer studies have explored how the behavior of these reporters changes in response to bulk viscosity.

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Complexity demands more flexibility and the prefrontal cortex has an answer.

Neuron

December 2024

University of Nevada, Las Vegas, Interdisciplinary Program in Neuroscience, Las Vegas, NV 89154-1003, USA; University of Nevada, Las Vegas, Department of Psychology, Las Vegas, NV 89154-1003, USA. Electronic address:

Cognitive flexibility allows us to adapt our behavior to keep up with a changing environment. In this issue of Neuron, Mugan and colleagues manipulate the complexity of an environment to demonstrate how the medial prefrontal cortex controls a cognitive flexibility circuit featuring the dorsolateral striatum and hippocampus.

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A study of impulsivity and adverse childhood experiences in a population health setting.

Front Public Health

December 2024

Department of Internal Medicine, School of Medicine, University of Nevada, Reno, Reno, NV, United States.

As complex mental health traits and life histories are often poorly captured in hospital systems, the utility of using the Barratt Impulsivity Scale (BIS) and Adverse Childhood Experiences (ACEs) for assessing adult disease risks is unknown. Here, we use participants from the Healthy Nevada Project (HNP) to determine if two standard self-assessments could predict the incidence and onset of disease. We conducted a retrospective cohort study involving adult participants who completed the Behavioral and Mental Health Self-Assessment (HDSA) between September 2018 and March 2024.

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To understand the potential benefits of emerging Alzheimer's disease (AD) therapies within and beyond clinical trial settings, there is a need to advance current outcome measurements into meaningful information relevant to all stakeholders. The relationship between the impact on disease biology and clinically measurable outcomes in cognition, function, and behavior must be considered when defining the meaningful benefit of early AD therapies. In this review, we discuss: (1) the lack of consideration for biomarkers in the current concept of meaningfulness in AD; (2) the lack of gold standards for determining minimal biologically and clinically important differences (MBCIDs) in AD trials; (3) how the treatment benefits of disease-modifying treatments are cumulative and increase over time; and (4) the different concepts of meaningfulness among key stakeholders.

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After nearly 50 years of searching, the vacuum ultraviolet Th nuclear isomeric transition has recently been directly laser excited and measured with high spectroscopic precision. Nuclear clocks based on this transition are expected to be more robust than and may outperform current optical atomic clocks. These clocks also promise sensitive tests for new physics beyond the standard model.

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On the anatomy of acoustic emission.

J Acoust Soc Am

December 2024

Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA.

Abrupt, local frictional fault failure comprises a displacement that is normally accompanied by acoustic emission (AE)-an impulsive elastic wave broadcast with an amplitude proportional to particle velocity. The aggregate of these displacements is the basic fault motion. In laboratory shear experiments, the examination of a sequence of laboratory earthquakes includes continuous measurements of fault motion and the associated AE that is broadcast.

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Alcohol use and alcohol-related mortality for pregnant and postpartum women have increased, and there are racial disparities in both alcohol consumption and pregnancy outcomes. In addition, data indicate that women of Color are more likely to experience many forms of violence and face more adverse consequences from violence than non-Hispanic White women. Therefore, the current study examined how the direct and indirect pathways between intimate partner violence (IPV), depressive symptoms, and alcohol consumption are moderated by both social support and race among postpartum women.

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Ophthalmoplegia in Seropositive Myasthenia Gravis and Concomitant Seropositive Anti-GQ1b Disease.

J Neuroophthalmol

December 2024

Departments of Neurology and Neuro-Ophthalmology (AV), Valley Hospital Medical Center, Las Vegas Neurology Center, Las Vegas, Nevada; University of Nevada Las Vegas School of Medicine (CD), Las Vegas, Nevada; Departments of Neurology (CN, PJ), Valley Hospital Medical Center, Las Vegas Neurology Center, Las Vegas, Nevada; McGovern Medical School (MYZ), University of Texas at Houston Health Science Center, Houston, Texas; Department of Ophthalmology (RI), University of Texas Medical Branch, Houston, Texas; Department of Ophthalmology (SAA), The University of Jordan, Amman, Jordan; Department of Ophthalmology (SAA, AGL), Houston Methodist Hospital, Houston, Texas; Ophthalmology (AGL), Blanton Eye Institute, Houston Methodist Hospital, Houston, Texas; Ophthalmology, Neurology, and Neurosurgery (AGL), Weill Cornell Medicine, New York, New York; Ophthalmology (AGL), UTMB Galveston, Texas A and M College of Medicine, and the UT MD Anderson Cancer Center, Houston, Texas; and Ophthalmology (AGL), Baylor College of Medicine, The University of Buffalo, Buffalo, New York, and the University of Iowa Hospitals and Clinics (AGL), Houston, Texas.

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We investigated the potential to improve motor learning and performance in people with multiple sclerosis (PwMS) with OPTIMAL theory conditions. OPTIMAL theory predicts that three main factors [i.e.

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Background: Falls and extremity fractures often occur in people living with Alzheimer's disease and related disorders (ADRD). In post-fracture care, these patients are cared for either at rehabilitation facilities or their homes. The coronavirus disease 2019 (COVID-19) pandemic limited the utilization of rehabilitation facilities.

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Objective: Prescription opioid-related deaths increased by 200 % from 2000 to 2014. There has been limited research regarding channels used by pharmaceutical companies to market prescription opioids. In this study, we investigated pharmaceutical industry use of key opinion leaders (KOLs).

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Local government policies and practices shape the context of the places that can alter a population's life chances through socioeconomic factors, built environments, and healthcare access. County governments, one of the most ubiquitous U.S.

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Designing Highly Potent Side-Chain Lactam-Bridged Cyclic Competence-Stimulating Peptide-Based Quorum-Sensing Modulators in .

ACS Infect Dis

December 2024

Department of Chemistry, University of Nevada, Reno, 1664 N. Virginia Street, Reno, Nevada 89557, United States.

, a Gram-positive bacterium found in the oral microbiome, shows promise as an oral probiotic for preventing dental caries. It exhibits a reverse correlation with , a key caries-causing pathogen, likely due to its production of hydrogen peroxide, a process mediated by quorum sensing (QS). In this work, we set out to develop novel lactam-based cyclic analogues of the competence stimulating peptide (CSP) signal utilized by for QS activation.

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Even though gene duplication is a key source of new genes and evolutionary innovation, it is unclear how duplicates survive the period immediately following gene duplication, in which both copies are functionally redundant. In the absence of epigenetic silencing, the abundance of the gene product would double after gene duplication, which would often have deleterious effects. However, recent duplicates exhibit low expression levels, which could be at least partially explained by high levels of promoter methylation.

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The global prevalence of obesity continues to rise. However, whether obesity affects the degree of intra-abdominal solid organ damage following blunt trauma remains unclear. This study aimed to investigate the correlation between obesity and intra-abdominal solid organ damage.

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Background/objectives: Public health administrators are entrusted to oversee the fair and efficient implementation of public health policy. Professional standards rooted in social justice add an additional ethical standard beyond what is required by procedural equality, reinforcing a service culture of creativity and doing more with less when resources are restrictive. This study explores this phenomenon within the context of government-subsidized opioid use disorder programming in Pennsylvania.

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Compassion is recognized as a key component of high-quality healthcare. The literature shows that compassion is essential to improving patient-reported outcomes and fostering health care professionals' (HCPs) response and resilience to burnout. However, compassion is inherently difficult to define, and a validated tool to reliably quantify and measure patients' experience of compassion in healthcare settings did not exist until recently.

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Modeling Clustered DNA Damage by Ionizing Radiation Using Multinomial Damage Probabilities and Energy Imparted Spectra.

Int J Mol Sci

November 2024

Department of Health Physics and Diagnostic Sciences, University of Nevada Las Vegas, 4505 S. Maryland Parkway, Box 453037, Las Vegas, NV 89154, USA.

Simple and complex clustered DNA damage represent the critical initial damage caused by radiation. In this paper, a multinomial probability model of clustered damage is developed with probabilities dependent on the energy imparted to DNA and surrounding water molecules. The model consists of four probabilities: (A) direct damage of sugar-phosphate moieties leading to SSB, (B) OH radical formation with subsequent SSB and BD formation, (C) direct damage to DNA bases, and (D) energy imparted to histone proteins and other molecules in a volume not leading to SSB or BD.

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The influence of family meals on nutrition and health for families has been understudied, especially in low- and middle-income countries. We aimed to analyze associations between regular family meals and body mass index (BMI), food consumption, eating, and sedentary behaviors among Brazilian schoolchildren and their caregivers. A cross-sectional study was conducted with 1887 Brazilian schoolchildren aged 6-11 years and their caregivers.

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