"Coming Home Is the Hardest Part": An Interpretative Phenomenological Analysis of Sense Making in Military Postdeployment Reintegration.

The purpose of the present interpretative phenomenological analysis (IPA) study was to understand how military service members and veterans (MSMVs) make sense of their reintegration experiences following deployment. IPA provides the ability to gain a deeper understanding of a shared experience, or phenomenon, such as reintegration following deployment. Data collection involved semi-structured interviews via Zoom.

Selective engagement of long-latency reflexes in postural control through wobble board training.

Long-latency reflexes (LLRs) are critical precursors to intricate postural coordination of muscular adaptations that sustain equilibrium following abrupt disturbances. Both disturbances and adaptive responses reflect excursions of postural control from quiescent Gaussian stability under a narrow bell curve, excursions beyond Gaussianity unfolding at many timescales. LLRs slow with age, accentuating the risk of falls and undermining dexterity, particularly in settings with concurrent additional tasks.

Effects of individually calibrated white and pink noise vestibular stimulation on standing balance of young healthy adults.

Imperceptible noisy galvanic vestibular stimulation (nGVS) improves standing balance due to the presence of stochastic resonance (SR). There is, however, a lack of consensus regarding the optimal levels and type of noise used to elicit SR like dynamics. We aimed to confirm the presence of SR behavior in the vestibular system of young healthy adults by examining postural responses to increasing amplitudes of white and pink noise stimulation scaled to individual cutaneous perceptual threshold.

IMPACT OF NOCTURNAL OXYGEN ENRICHMENT ON HIGH-ALTITUDE ACCLIMATIZATION.

Nocturnal oxygen enrichment improves sleep at high-altitude but may impair acclimatization. Determine if nocturnal oxygen enrichment impacts acclimatization. A 7-day acclimatization protocol occurred at a field-based research site between 0-4200m.

Advancements of paper-based sensors for antibiotic-resistant bacterial species identification.

Evolution of antimicrobial-resistant bacterial species is on a rise. This review aims to explore the diverse range of paper-based platforms designed to identify antimicrobial-resistant bacterial species. It highlights the most important targets used for sensor development and examines the applications of nanosized particles used in paper-based sensors.

DNA methylation patterns of circadian and ultradian genes are altered in the peripheral blood of patients with hidradenitis suppurativa.

Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that affects hair follicles in areas with apocrine sweat glands, such as the underarms, groin, and buttocks. The pathogenesis of HS is not fully understood, but considering the key role played by the biological clock in the control of immune/inflammatory processes the derangement of circadian and ultradian pathways could be hypothesized.

Methods: We analyzed genome-wide DNA methylation patterns in peripheral blood from 24 HS cases and 24 controls using the Infinium HumanMethylation450 BeadChip array (Illumina), followed by bioinformatics and statistical analyses.

Development and Feasibility of a Conversation Tool to Garner Mental Health and Intimate Partner Violence History from Patients Seeking Pelvic Healthcare: A Trauma-Informed Approach.

A conversation tool was developed by a clinician/researcher partnership to garner mental health and intimate partner violence histories from patients seeking pelvic healthcare. A 3-stage mixed measures approach with healthcare providers ( = 22) and victim service experts ( = 8) was utilized to meet study aims. The finalized conversation tool was found to have satisfactory face and content validity as well as to be feasible to implement in clinical settings based on constructs related to acceptability, practicality, demand, and implementation.

Characterization of biofilms through ethyl methanesulfonate mutagenesis.

is a coagulase-negative species responsible for a multitude of infections. These infections often resemble those caused by the more pathogenic staphylococcal species, , such as skin and soft tissue infections, prosthetic joint infections, and infective endocarditis. Despite a high mortality rate and infections that differ from other coagulase-negative species, little is known regarding pathogenesis.

Levodopa-induced dyskinesia alters postural control in people with Parkinson's disease.

While levodopa is the most effective drug for symptom treatment of Parkinson's Disease (PD), its long-term use often leads to side effects such as uncontrolled involuntary movements known as levodopa-induced dyskinesia (LID). LID has been shown to increase postural sway, but the extent to which these hyperkinetic movements alter postural sway strategies has not been explored. We recruited 25 people with idiopathic PD, of which 13 exhibit clinical signs of LID, and 10 healthy older adults.

Effects of Supervised Exercise Therapy on Muscle Function During Walking in Patients with Peripheral Artery Disease.

Background: Although supervised exercise therapy (SET) is a primary treatment for peripheral artery disease (PAD), the current literature is limited regarding the mechanisms contributing to increased walking distances, including how lower extremity muscle function is altered after SET. This study aimed to investigate the effects of SET on lower extremity muscle function during walking in patients with PAD.

Methods: Twelve patients with PAD participated in a 6-month SET program consisting of three weekly exercise sessions (a total of 72 sessions) and adhered to the American College of Sports Medicine's (ACSM) recommendations.

A novel computational approach for the mining of signature pathways using species co-occurrence networks in gut microbiomes.

Background: Advances in metagenome sequencing data continue to enable new methods for analyzing biological systems. When handling microbial profile data, metagenome sequencing has proven to be far more comprehensive than traditional methods such as 16s rRNA data, which rely on partial sequences. Microbial community profiling can be used to obtain key biological insights that pave the way for more accurate understanding of complex systems that are critical for advancing biomedical research and healthcare.

When Is Teasing Abuse? A Grounded Theory of Teasing Among Mexican American Adolescent Dating Couples.

This study examined the use of teasing during observed videotaped interactions of Mexican American adolescent dating couples ( = 34; 15-17 years old) from an urban area of the Southwest United States. During the interaction task, couples discussed two relationship problems for 14 min and nearly all interactions (88.2%) contained teasing.

A systematic review of human odometry.

Human odometry refers to an individual's ability to travel between locations without eyesight and without designating a conscious effort toward spatially updating themselves as they travel through the environment. A systematic review on human odometry was completed for the purpose of establishing the state-of-the-art of the topic, and based on this information, develop meaningful hypotheses using Strong Inference. The following databases were searched up to February 16, 2023, and accessed through University of Nebraska at Omaha proxied databases: IEEEXplore, PsycArticles, PsycInfo, PubMed Central, SCOPUS, and Web of Science.

Ball Don't Lie: Commentary on Chemero (2024) and Wallot et al. (2024).

The interaction-dominant approach to perception and action, originally formulated in the mid-1990s, has matured and gained remarkable momentum as an entailment of the dynamical hypotheses proposed at that time. This framework seeks to explain the fluid and intricate interplay of causality spanning the entire organism by integrating high-dimensional details with low-dimensional constraints across various scales of behavior. Both Chemero (2024) and Wallot et al.

Lower maximal skin wettedness in both warm-humid and hot-dry environments with advanced age (PSU HEAT project).

Maximum skin wettedness (ω) is the proportion of the body covered in sweat at the upper limit of compensable heat stress. It has yet to be determined how ω changes with aging. We examined variability in ω at the upper limit of compensable heat stress in warm-humid (WH) and hot-dry (HD) environments in young (Y, 18-29 yr), middle-aged (MA, 40-60 yr), and older (O, 65-89 yr) adults during minimal activity (MinAct; ∼1.

The combined influences of local heat application and resistance exercise on the acute mRNA response of skeletal muscle.

Introduction: The development and maintenance of the skeletal muscle is crucial for the support of daily function. Heat, when applied locally, has shown substantial promise in the maintenance of the muscle. The purpose of this study was to determine the combined effects of local heat application and acute resistance exercise on gene expression associated with the human muscle growth program.

Comparison of gait deviation index (GDI) and gait variability index (GVI) measured by marker-based and markerless motion capture systems in children with cerebral palsy (CP).

Background: The Gait Deviation Index (GDI) is a metric clinicians use to assess overall gait pathology in children with cerebral palsy (CP) by comparing kinematic data to a normative sample. The Gait Variability Index (GVI) is a related metric that quantifies the variability in spatio-temporal variables during gait. The GDI and GVI have been verified using marker-based motion capture approaches, but video-based markerless motion capture has not been compared using these tools in children with CP.

Housing and Husbandry Factors Affecting Zebrafish () Novel Tank Test Responses: A Global Multi-Laboratory Study.

The reproducibility crisis in bioscience, characterized by inconsistent study results, impedes our understanding of biological processes and global collaborative studies offer a unique solution. This study is the first global collaboration using the zebrafish () novel tank test, a behavioral assay for anxiety-like responses. We analyzed data from 20 laboratories worldwide, focusing on housing conditions and experimental setups.

Increased risks of Maternal Mental Health Conditions Following the COVID-19 Pandemic.

Background: Women are at an increased risk of developing psychiatric conditions such as anxiety and depression during pregnancy. Psychiatric conditions during pregnancy can put mothers and fetuses at risk of worse physical and mental health before, during, and after the completion of a pregnancy. Previous research indicates that women pregnant during COVID-19 were at a greater risk of developing mental health conditions and being exposed to stressors.

Metabolic Compensation Associated With Digestion in Response to the Latitudinal Thermal Environment Across Populations of the Prairie Lizard (Sceloporus consobrinus).

Environmental temperatures directly affect physiological rates in ectotherms by constraining the possible body temperatures they can achieve, with physiological processes slowing as temperatures decrease and accelerating as temperatures increase. As environmental constraints increase, as they do northward along the latitudinal thermal gradient, organisms must adapt to compensate for the slower physiological processes or decreased opportunity time. Evolving faster general metabolic rates is one adaptive response posited by the metabolic cold adaptation (MCA) hypothesis.

Single-Dose Drug Development Candidate for Schistosomiasis.

Aryl hydantoins were identified in the early 1980s as a promising antischistosomal chemotype. However, as exemplified by Ro 13-3978, this compound series produced antiandrogenic side effects on the host, a not unexpected outcome given their structural similarity to the antiandrogenic drug nilutamide. The two key advances in our optimization of Ro 13-3978 were swapping the aryl trifluoromethyl substituent with a difluoroethyl to abolish antiandrogenic effects and replacing the hydrogen atoms of the -dimethyl substructure with deuterium atoms to increase metabolic stability.

Dynamics of Motor Skill Learning in American and Israeli Toddlers With Varied Language Proficiency.

Purpose: The aim of the present study was twofold: to determine if deficits in motor skill proficiency and learning were present in 2-year-old children identified with early expressive language delay compared to peers without the delay, and to distinguish how motor skill proficiency and learning behaviors may manifest differently across culturally and linguistically diverse backgrounds.

Method: The study involved 54 children (24-36 months of age), 23 of whom were identified as having an expressive language delay. Furthermore, 16 participants were American and English-speaking and 38 were Israeli and Hebrew-speaking.