105 results match your criteria: "University of Nebraska Medical Center College of Medicine[Affiliation]"

Article Synopsis
  • The study explored how circadian rhythms affect blood clotting and cardiovascular risks in aspirin-treated patients with Type II Diabetes Mellitus (T2DM), particularly looking at fluctuations during different times of day.* -
  • Results showed that the R-value, indicating thrombotic risk, was lower during early morning awakening hours compared to other times, and pulse pressure was highest in the morning, suggesting increased risk for thrombotic events when waking up.* -
  • The findings highlight the need to investigate chronotherapy as a potential strategy to reduce clotting and improve health outcomes in high-risk populations, such as diabetics with various cardiovascular risk factors.*
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Nighttime eating has been associated with obesity, inflammation, and poor nutritional intake, yet correlates of this behavior are understudied in pediatric populations and among adolescents in particular. The current study examines modifiable factors related to nighttime eating, including sleep parameters and regulatory abilities-as well as the interplay between these constructs-in adolescents. A total of 223 adolescents (M = 15.

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In 2013, Next Accreditation System and Milestones became the competency-based assessment framework required for all specialties accredited by the Accreditation Council for Graduate Medical Education. Dermatology residency programs implemented Milestones 1.0 in the 2013-2014 academic year.

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Background: Congenital diaphragmatic hernia (CDH) accounts for 8% of all major congenital anomalies. Neonates who are small for gestational age (SGA) generally have a poorer prognosis. We sought to identify risk factors and variables associated with outcomes in neonates with CDH who are SGA in comparison to neonates who are appropriate for gestational age (AGA).

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A 24-year-old woman presented to the emergency department with symptoms consistent with an ectopic pregnancy. Ultrasonographic evaluation reported no evidence of intrauterine pregnancy, a heterogenous mass in the left adnexa, and normal-appearing bilateral ovaries. The right kidney was imaged, though the left kidney was not visualized.

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Managing Fractures and Sprains.

Prim Care

March 2022

Department of Family Medicine, Offutt AFB/UNMC Family Medicine Residency Program, University of Nebraska Medical Center College of Medicine, 983075 Nebraska Medical Center, Omaha, NE 68198-3075, USA.

Primary care physicians are often the first to evaluate patients with extremity injuries. Identification of fractures and sprains and their proper management is paramount. After appropriate imaging is obtained, immobilization and determination of definitive management, either nonoperative or operative, is critical.

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Rationale: Concern for immune-related adverse events from immunotherapy and radiation therapy are well-documented; however, side effects are mostly mild to moderate. However, high-grade, potentially life-threatening adverse events are increasing. While case reports regarding immunotherapy-related bullous pemphigoid (BP) have been rising, only 1 has described BP following concomitant use of both nivolumab and radiation therapy (RT).

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Objectives: This study aims to assess characteristics of same-day clinic appointments in a pediatric population at an academic otolaryngology practice.

Methods: Retrospective chart review of patients aged 18 or younger who had same-day clinic appointments between January 1, 2016, and December 31, 2018, at a single academic institution. Demographic data, diagnosis(es), procedures, and operations completed were included in the analysis.

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Management of Incidentalomas.

Surg Clin North Am

December 2021

Department of Surgery, Division of Surgical Oncology, University of Nebraska Medical Center, 986880 Nebraska Medical Center, Omaha, NE 68198-6880, USA. Electronic address:

Incidental findings are common in the evaluation of surgical patients. Understanding the appropriate assessment and management of these frequent occurrences is important for the provision of comprehensive quality care. This review details the epidemiology, considerations, and recommendations for management of common incidental manifestations in surgical patients, including Meckel diverticulum, adrenal incidentaloma, thyroid nodule, solitary pulmonary nodule, small bowel intussusception, gallstones, and incidental appendectomy.

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ALSUntangled #63: ketogenic diets.

Amyotroph Lateral Scler Frontotemporal Degener

February 2023

Neurology Department, Mass General Brigham Inc., Boston, MA, United States.

ALSUntangled reviews alternative and off label treatments with a goal of helping patients make more informed decisions about them. Here we review ketogenic diets. We shows that these have plausible mechanisms, including augmenting cellular energy balance and reducing excitotoxicity, neuroinflammation and oxidative stress.

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Rare and de novo variants in 827 congenital diaphragmatic hernia probands implicate LONP1 as candidate risk gene.

Am J Hum Genet

October 2021

Department of Pediatrics, Columbia University Irving Medical Center, New York, NY 10032, USA; Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA. Electronic address:

Article Synopsis
  • * A study found important genetic variants in the LONP1 and ALYREF genes, with LONP1 showing a significant role in CDH risk through both new and rare inherited mutations.
  • * Research on mice lacking Lonp1 revealed severe lung issues, supporting the gene's critical role in lung development and the associated high mortality in CDH cases.
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The Use of Methylene Blue during Liver Transplantation for Vasoplegia.

Case Rep Anesthesiol

June 2021

University of Nebraska Medical Center-Department of Anesthesiology, Nebraska Medical Center, Omaha 68198-7541, NE, USA.

The use of methylene blue for vasoplegia in cardiac cases with cardiopulmonary bypass, septic shock, and acute liver failure is well documented. Use of MB for liver transplantation has been largely limited to case reports. We describe three separate liver transplantation patients with significant hypotension following reperfusion.

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Introduction: Faculty development (FD) is an element critical to the professional growth of medical educators and a necessary component in developing effective educators. FD offerings are prevalent across academic institutions; however, faculty report they are unable to participate in these initiatives due to time limitations and competing priorities. The snippet FD approach can address these concerns but requires training for FD providers to be effectively used.

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Participatory needs assessment and action planning for a clinical and translational research network.

J Clin Transl Sci

December 2020

Great Plains IDeA-Clinical and Translational Research Network, Omaha, NE, USA.

The goal of this study was to assess the utility of participatory needs assessment processes for continuous improvement of developing clinical and translational research (CTR) networks. Our approach expanded on evaluation strategies for CTR networks, centers, and institutes, which often survey stakeholders to identify infrastructure or resource needs, using the case example of the Great Plains IDeA-CTR Network. Our 4-stage approach (i.

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We report a case of varicella zoster virus (VZV)-associated anterior uveitis in a patient with weight loss, arthritis and signs of inflammatory bowel disease. Her clinical course included the development of a thalamic stroke secondary to VZV cerebral vasculopathy. Following antiviral therapy, the patient's neurologic symptoms recovered and her ophthalmic findings improved.

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Improving the Residency Program Virtual Open House Experience: A Survey of Urology Applicants.

Urology

December 2020

University of Nebraska Medical Center - College of Medicine, Omaha, NE; Division of Urologic Surgery, University of Nebraska Medical Center and Nebraska Medicine, Omaha, NE. Electronic address:

Objective: To investigate the perception and value of virtual open houses for urology applicants in the COVID-19 era, since students can no longer attend subinternships and all interviews will be conducted virtually.

Methods: A Twitter survey was sent to 230 likely urology applicants connected through the UroResidency platform. It asked about the relative value of components of the virtual open house and areas for suggested improvement.

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Malignant Melanoma: a Rare Cause of Obstructive Jaundice.

J Gastrointest Surg

April 2021

Division of Gastroenterology and Hepatology, University of Nebraska Medical Center, 982000 Nebraska Medical Center, Omaha, NE, 68198-2000, USA.

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In 2016 worldwide, 1.8 million people were newly infected with HIV. About 36.

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Importance: Between 2 and 3.5 million people live with chronic hepatitis C virus (HCV) infection in the US, most of whom (approximately 75%) are not aware of their disease. Despite the availability of effective HCV treatment in the early stages of infection, HCV will result in thousands of deaths in the next decade in the US.

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Chronic pain management during the coronavirus disease 2019 (COVID-19) pandemic is a challenging process, especially with growing evidence that COVID-19 infection is associated with myalgias, referred pain, and widespread hyperalgesia. In light of the limited data available for COVID-19-related impact on chronic pain patients, this review explores the changes in the healthcare delivery system due to social distancing and safety precautions to provide the appropriate management of chronic pain patients during the COVID-19 pandemic. Understanding both the general problems facing chronic pain patients as well as specific problems in the COVID-19 era including deconditioning, increased mental health concerns, financial burdens, and potential for medication-induced immune-suppression is vital in the appropriate management of patients.

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