Historical, psychopathological, neurological, and neuropsychological aspects of deficit schizophrenia: a multicenter study.

Objective: This multicenter study aimed to verify whether the historical and psychopathological characteristics of a large group of patients with deficit schizophrenia were consistent with those reported in previous studies. The authors also tested the hypothesis that neurological and neuropsychological indices sensitive to frontoparietal dysfunction, but not those sensitive to temporal lobe dysfunction, are more impaired in patients with deficit schizophrenia than in those with non-deficit schizophrenia.

Method: For each patient with deficit schizophrenia enrolled in the study, a matched subject with non-deficit schizophrenia was recruited.