3 results match your criteria: "University of Munich and Center for Integrated Protein Science (CIPSM)[Affiliation]"
Author Correction: Optical control of L-type Ca channels using a diltiazem photoswitch.
Nat Chem Biol
March 2021
Department of Chemistry, University of Munich and Center for Integrated Protein Science (CIPSM), Munich, Germany.
Optical control of L-type Ca channels using a diltiazem photoswitch.
Nat Chem Biol
August 2018
Department of Chemistry, University of Munich and Center for Integrated Protein Science (CIPSM), Munich, Germany.
L-type Ca channels (LTCCs) play a crucial role in excitation-contraction coupling and release of hormones from secretory cells. They are targets of antihypertensive and antiarrhythmic drugs such as diltiazem. Here, we present a photoswitchable diltiazem, FHU-779, which can be used to reversibly block endogenous LTCCs by light.
View Article and Find Full Text PDFExploring the pharmacology and action spectra of photochromic open-channel blockers.
Chembiochem
August 2012
Department of Chemistry, University of Munich and Center for Integrated Protein Science-CIPSM, Butenandtstrasse 5-13, 81377 Munich, Germany.