2,103 results match your criteria: "University of Missouri--St Louis[Affiliation]"

Article Synopsis
  • Chemokines are crucial proteins in the immune system that help regulate inflammation by attracting leukocytes; targeting and inhibiting them is a key anti-inflammatory strategy.
  • The study describes a method for producing fluorescently labeled chemokines using recombinant DNA techniques and custom enzymes, which is cost-effective compared to commercial reagents.
  • The resulting fluorescent chemokine (vMIP-fluor) was successfully used in binding studies, showcasing its potential in anti-inflammatory therapies and demonstrating its effectiveness in competition assays with other chemokines.
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Achieving Health Equity and Continuity of Care for Black and Latinx People Living With HIV.

Am J Public Health

June 2023

Tamra Burns Loeb, Enricka Norwood-Scott, Muyu Zhang, Gail E. Wyatt, and Alison B. Hamilton are with the Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA). Gail E. Wyatt and Alison B. Hamilton are also guest editors of this special issue. Devin Banks is with the Department of Psychological Sciences, University of Missouri‒St Louis. Kate Ramm is with the Department of Medicine‒Endocrinology Division, UCLA Health. Isabella Viducich is with Jennifer Keaney and Associates Inc, Los Angeles. Quonta Beasley is with the Graduate School of Education and Psychology, Pepperdine University, Los Angeles. Juan Barron and Arleen F. Brown are with the Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine, UCLA. Elizabeth Lee Chen is with the Fielding School of Public Health, UCLA. Kimberly Fuentes is with the Luskin School of Public Affairs, UCLA.

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Objective: Black youth with high body weights [BYHW; Body Mass Index (BMI)≥95th percentile] endure unique stressors (e.g., exposure to discrimination due to race and size) that may contribute to psychopathology.

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Premise: Many tropical plants are bat-pollinated, but these mammals often carry copious, multispecific pollen loads making bat-pollinated plants susceptible to heterospecific pollen deposition and reproductive interference. We investigated pollen transfer between sympatric bat-pollinated Burmeistera species and their response to heterospecific pollen deposition from each other.

Methods: We quantified conspecific and heterospecific pollen deposition for two populations of B.

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The comprehensive model of information seeking (CMIS) is a well-known framework to predict health information seeking by a combination of health beliefs and medium-related factors. Despite being proposed almost three decades ago, few efforts have been made to systematically summarize CMIS scholarship. To fill this gap in the literature, 36 meta-analyses were first conducted to identify the bivariate relationships between variables in the CMIS.

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Background: After experiencing a traumatic event, two possible outcomes are experiencing positive changes, such as posttraumatic growth (PTG), and/or experiencing distress in the form of posttraumatic stress symptoms (PTSS). These constructs are not mutually exclusive; those who experience PTSS may concurrently or at a later date likewise undergo PTG. Pretrauma factors, such as personality as measured by the Big Five Inventory (BFI), can interact with both PTSS and PTG.

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Background: Emotion dysregulation is key to the development and maintenance of chronic pain, feeding into a cycle of worsening pain and disability. Dialectical behavioral therapy (DBT), an evidence-based treatment for complex transdiagnostic conditions presenting with high emotion dysregulation, may be beneficial to manage and mitigate the emotional and sensory aspects of chronic pain. Increasingly, DBT skills training as a key component of standard DBT is being delivered as a stand-alone intervention without concurrent therapy to help develop skills for effective emotion regulation.

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Introduction: Low- and middle-income countries shoulder a disproportionate burden of mental health disorders with limited resources to support the provision of care using culturally relevant, evidence-based interventions. This is particularly true in Cambodia where the population continues to confront traumatic consequences of the Khmer Rouge genocide that targeted educated people, including treatment providers. Trauma-Informed Treatment Algorithms for Advancing Novel Outcomes (Project TITAN) will examine proof of concept and preliminary efficacy of culturally tailored interventions for symptoms of post-traumatic stress (PTS) among Cambodian adults.

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Attitudes Toward Medication for Opioid Use Disorder Among Pregnant and Postpartum Women and People Seeking Treatment.

J Addict Med

June 2023

From the Department of Psychological Sciences, University of Missouri-St. Louis, St. Louis, MO (DEB, MP); and Washington University School of Medicine, St Louis, MO (AF, XL, LF, CW, PC-R).

Objectives: Pregnant and postpartum women and people (PPWP) who use opioids experience higher rates of morbidity, preterm labor, and stillbirth than those who do not. Although medication for opioid use disorder (MOUD) is the standard of treatment, utilization among PPWP has remained low because of MOUD stigma and misconceptions. The current report examined general and pregnancy-related MOUD attitudes, norms, and self-efficacy among PPWP seeking treatment.

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Article Synopsis
  • - This study investigated the impact of HIV on resting state functional connectivity (RSFC) by comparing a large group of people with HIV (PWH) to healthy controls without HIV (PWoH).
  • - Using brain scans from 316 PWH and 209 PWoH, researchers analyzed the influence of viral load and cognitive impairment on RSFC, but did not find any significant differences between groups.
  • - The findings suggest that HIV does not significantly affect RSFC in this cohort, and future research may benefit from larger samples and additional imaging techniques.
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Article Synopsis
  • The third wave of the opioid crisis, marked by the rise of fentanyl, has led to increased overdose deaths and significant racial disparities affecting Black Americans.
  • The study conducted in St. Louis examined the geographic patterns of opioid overdose deaths before and during the fentanyl era, revealing that overdose deaths became more concentrated in predominantly Black neighborhoods.
  • The findings highlight the urgent need for policy interventions in high-deprivation communities to address the growing impact of the opioid crisis on Black populations.
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The Mar, Sox, and Rob Systems.

EcoSal Plus

December 2023

Department of Biology, University of Missouri-St. Louis, St. Louis, Missouri, USA.

Environments inhabited by are diverse and often stressful. This is particularly true for and during host association in the gastrointestinal systems of animals. There, and must survive exposure to various antimicrobial compounds produced or ingested by their host.

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Experiences of racial discrimination are pervasive among Black youth, resulting in psychosocial problems such as depression and anxiety. Rumination plays a key role in linking racial discrimination and internalizing concerns. Developmental age has also been shown to influence the extent to which racial discrimination and rumination impact mental health; however, studies have yet to explore the interplay between these factors.

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Objective: Nurses' voluntary reporting of adverse events and errors is critical for improving patient safety. The operationalization and application of the concept, patient safety culture, warrant further study. The objectives are to explore the underlying factor structure, the correlational relationship, between items of the Agency for Healthcare Research and Quality Hospital Survey on Patient Safety Culture and examine its construct validity.

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The endophytobiome of wild Rubiaceae as a source of antagonistic fungi against the American Leaf Spot of coffee (Mycena citricolor).

J Appl Microbiol

May 2023

Centro de Investigaciones en Productos Naturales (CIPRONA) and Escuela de Biología, Universidad de Costa Rica, San Pedro, San José 11801, Costa Rica.

Aims: The American leaf spot, caused by Mycena citricolor, is an important disease of coffee (Coffea arabica), mostly in Central America. Currently, there are limited pathogen control alternatives that are environment friendly and economically accessible. The use of fungi isolated from the plant endomycobiota in their native habitats is on the rise because studies show their great potential for biological control.

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Monitoring lipid-protein interactions in planta using Förster resonance energy transfer.

Methods Enzymol

April 2023

Department of Biology, University of Missouri-St. Louis, St. Louis, MO, United States; Donald Danforth Plant Science Center, St. Louis, MO, United States. Electronic address:

Phospholipids are not only the major structural components of cellular membranes but also important signaling molecules regulating various cellular and physiological processes. One mode of action by lipid mediators is via lipid-protein interactions to modulate the downstream cellular events. An increasing number of lipid-binding proteins have been identified using in vitro lipid-protein binding assays, but it has been challenging to monitor lipid-protein interactions in vivo.

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Objective: To examine profiles of distress of mothers of preterm infants in the neonatal intensive care unit (NICU) and relate profiles to maternal and child outcomes at child age 5 years.

Method: A racially and economically diverse sample of mothers (n = 94; 39% African American, 52% White) of preterm infants (≤30 weeks of gestation) completed validated questionnaires assessing depression, anxiety (state and trait), NICU stress, and life stress at NICU discharge of their infant. Mothers reported on their own and their children's symptomatology at child age 5.

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Puf3p regulates the stability of nuclear-encoded mRNAs acting in mitochondrial biogenesis and function in Saccharomyces cerevisiae. This work identifies the phosphorylation of Pop2p, a component of the deadenylase complex, as being critical for adapting Puf3p-mediated mRNA decay upon carbon source alterations. We demonstrate that the Puf3p-Pop2p association diminishes in mitochondria-reliant conditions and establish Yak1p, a kinase that phosphorylates Pop2p at threonine 97, as a new player in Puf3p-mediated regulation of mRNA decay.

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Although frequently hypothesized, the evidence for associations between affect and marijuana use in everyday life remains ambiguous. Inconsistent findings across existing work may be due, in part, to differences in study design and analytic decisions, such as study inclusion criteria, the operationalization of affect, or the timing of affect assessment. We used specification curves to assess the robustness of the evidence for affect predicting same-day marijuana use and marijuana use predicting next-day affect across several hundred models that varied in terms of decisions that reflect those typical in this literature (e.

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Objective: This article conceptually examined the need for and utility of community-based participatory research (CBPR) approaches for increasing rates of engagement in psychological research among underserved minoritized ethnoracial groups.

Methods: This article examined the literature for relevant studies examining rates of research engagement by minoritized ethnoracial groups, significant factors precluding research engagement, and the consequences of this disparity for mental health outcomes. The theoretical literature outlining the development and utility of alternative, community-based participatory research methods was included.

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Composition and function of the Galapagos penguin gut microbiome vary with age, location, and a putative bacterial pathogen.

Sci Rep

April 2023

Department of Biology and Whitney R. Harris World Ecology Center, University of Missouri-St. Louis, One University Blvd., St. Louis, MO, 63121, USA.

Article Synopsis
  • Microbial colonization influences host health, and studying the gut microbiome of species, like the endangered Galapagos penguin, is crucial for understanding how to monitor diseases in wild populations.
  • Researchers collected fecal samples from wild penguins to analyze their gut microbiome composition, discovering dominant bacterial phyla and a focus on metabolic functions, along with identifying the presence of potential pathogens, particularly Clostridium perfringens.
  • The study found that factors such as developmental stage, location, and potential pathogens impact the diversity of the microbial community, with juvenile penguins showing significantly lower diversity compared to adults.
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