Revictimization Risk Factors Following Childhood Maltreatment: A Literature Review.

Revictimization research, to date, has primarily focused on sexual revictimization (i.e., child sexual abuse and adult sexual assault), which has resulted in a lack of understanding of trauma revictimization more generally.

Size matters: DNA binding site kinetics as a function of polyamide size.

Hairpin polyamides (PAs) are remarkable minor groove-binding DNA ligands that demonstrate high affinity and sequence selectivity. Following extensive studies of 6-8 ring hairpin PAs have been more recent descriptions of larger PAs (14 rings or more) and their distinguishing properties and biological activities. However, there are no comparative kinetic studies of PA DNA binding behaviors over a range of PA sizes, making it difficult to understand important structure-activity relationships related to PA size.

Oligonucleotides containing abasic threoninol-terpyridine residues as potential artificial ribonucleases.

Artificial ribonucleases, also known as synthetic ribozymes, were synthesized with an internal, stereochemically-pure, abasic threoninol backbone-residue to which the RNA transesterification catalyst copper (II) terpyridine was covalently linked. These oligonucleotide conjugates were constructed to determine if the stereochemistry of the abasic threoninol backbone residue influences the transesterification rate of complementary RNA oligonucleotides. Following synthesis, these compounds were reacted with complementary 28-mer and 159-mer RNA substrates and their relative transesterification efficiencies were determined.

HIV-1 subtype C Tat exon-1 amino acid residue 24K is a signature for neurocognitive impairment.

Variation and differential selection pressures on Tat genes have been shown to alter the biological function of the protein, resulting in pathological consequences in a number of organs including the brain. We evaluated the impact of genetic variation and selection pressure on 147 HIV-1 subtype C Tat exon 1 sequences from monocyte-depleted peripheral lymphocytes on clinical diagnosis of neurocognitive impairment. Genetic analyses identified two signature amino acid residues, lysine at codon 24 (24K) with a frequency of 43.

Scoring protein sequence alignments using deep learning.

Motivation: A high-quality sequence alignment (SA) is the most important input feature for accurate protein structure prediction. For a protein sequence, there are many methods to generate a SA. However, when given a choice of more than one SA for a protein sequence, there are no methods to predict which SA may lead to more accurate models without actually building the models.

Social Functioning in Individuals Affected by Childhood Maltreatment: Establishing a Research Agenda to Inform Interventions.

Childhood maltreatment (CM) is linked to impairments in various domains of social functioning. Here, we argue that it is critical to identify factors that underlie impaired social functioning as well as processes that mediate the beneficial health effects of positive relationships in individuals exposed to CM. Key research recommendations are presented, focusing on: (1) identifying attachment-related alterations in specific inter- and intrapersonal processes (e.

Relational Factors Associated With Posttraumatic Stress Among Emerging Adults of Color Exposed to Community Violence.

The relationship between trauma exposure and posttraumatic stress symptoms (PTSS) is well-documented, but less is known about factors that contribute to the expression of PTSS following community violence exposure, particularly among emerging adults of color. Utilizing the Person-Environment Interaction model (Slaug et al., 2018), this study examined the role of relational factors, specifically ethnic identity, community cohesion, and social support, associated with PTSS following exposure to community violence.

An Exploratory Study of Sexual Aggression Tactics as a Function of Perpetrator Gender and Victim Gender.

This study sought to examine the association between perpetrator gender and victim gender and the use of sexually aggressive tactics (e.g., persistent enticement, verbal pressure, taking advantage of the inability to consent, and ignoring explicit non-consent).

WMR-DepthwiseNet: A Wavelet Multi-Resolution Depthwise Separable Convolutional Neural Network for COVID-19 Diagnosis.

Timely discovery of COVID-19 could aid in formulating a suitable treatment plan for disease mitigation and containment decisions. The widely used COVID-19 test necessitates a regular method and has a low sensitivity value. Computed tomography and chest X-ray are also other methods utilized by numerous studies for detecting COVID-19.

COVID-19 Diagnosis from Chest X-ray Images Using a Robust Multi-Resolution Analysis Siamese Neural Network with Super-Resolution Convolutional Neural Network.

Chest X-ray (CXR) is becoming a useful method in the evaluation of coronavirus disease 19 (COVID-19). Despite the global spread of COVID-19, utilizing a computer-aided diagnosis approach for COVID-19 classification based on CXR images could significantly reduce the clinician burden. There is no doubt that low resolution, noise and irrelevant annotations in chest X-ray images are a major constraint to the performance of AI-based COVID-19 diagnosis.

Fine-Tuned Siamese Network with Modified Enhanced Super-Resolution GAN Plus Based on Low-Quality Chest X-ray Images for COVID-19 Identification.

Coronavirus disease has rapidly spread globally since early January of 2020. With millions of deaths, it is essential for an automated system to be utilized to aid in the clinical diagnosis and reduce time consumption for image analysis. This article presents a generative adversarial network (GAN)-based deep learning application for precisely regaining high-resolution (HR) CXR images from low-resolution (LR) CXR correspondents for COVID-19 identification.

COVID-19 Pneumonia Classification Based on NeuroWavelet Capsule Network.

Since it was first reported, coronavirus disease 2019, also known as COVID-19, has spread expeditiously around the globe. COVID-19 must be diagnosed as soon as possible in order to control the disease and provide proper care to patients. The chest X-ray (CXR) has been identified as a useful diagnostic tool, but the disease outbreak has put a lot of pressure on radiologists to read the scans, which could give rise to fatigue-related misdiagnosis.

A Preliminary Study on Up-regulation of Sexual Desire for a Long-term Partner.

Background: Declining sexual desire over the course of a relationship may cause distress. Because sexual desire partly depends on who the (imagined) sexual partner is, this study focuses on increasing sexual desire for the long-term partner specifically.

Aim: This study examined 3 regulation strategies: (i) positive reappraisal of the partner, (ii) reappraisal of sexual desire decline, and (iii) sexual imagery about the partner.

Focusing Narrowly on Model Fit in Factor Analysis Can Mask Construct Heterogeneity and Model Misspecification: Applied Demonstrations across Sample and Assessment Types.

This study builds upon research indicating that focusing narrowly on model fit when evaluating factor analytic models can lead to problematic inferences regarding the nature of item sets, as well as how models should be applied to inform measure development and validation. To advance research in this area, we present concrete examples relevant to researchers in clinical, personality, and related subfields highlighting two specific scenarios when an overreliance on model fit may be problematic. Specifically, we present data analytic examples showing that focusing narrowly on model fit may lead to (a) incorrect conclusions that heterogeneous item sets reflect narrower homogeneous constructs and (b) the retention of potentially problematic items when developing assessment measures.

Age Difference in Roles of Perceived Social Support and Psychological Capital on Mental Health During COVID-19.

Due to the outbreak of the Coronavirus Disease-2019 (COVID-19) pandemic and consequent confinement measures, young people are vulnerable to mental health problems. The current study compared a group of 440 young adolescents (10-12 years) and a group of 330 emerging adults (18-25 years) to investigate the extent to which perceived social support and psychological capital (PsyCap) were differentially associated with mental health problems. Participants were asked to report their current psychosocial adaptation status during the COVID-19 pandemic, and data were collected via online questionnaires during a relatively severe period of COVID-19 in China.

Bumble bees exhibit body size clines across an urban gradient despite low genetic differentiation.

Environmental heterogeneity resulting from human-modified landscapes can increase intraspecific trait variation. However, less known is whether such phenotypic variation is driven by plastic or adaptive responses to local environments. Here, we study five bumble bee (Apidae: Bombus) species across an urban gradient in the greater Saint Louis, Missouri region in the North American Midwest and ask: (1) Can urban environments induce intraspecific spatial structuring of body size, an ecologically consequential functional trait? And, if so, (2) is this body size structure the result of plasticity or adaptation? We additionally estimate genetic diversity, inbreeding, and colony density of these species-three factors that affect extinction risk.

Faith Community Nursing: Improving Self-Care in Minority Church Members Through Patient Activation.

Spirituality and faith, which are cornerstones of African American churches, also create a receptive setting for health improvement activities. This article presents participant responses to a health improvement intervention to promote church members' self-care. Using the Body & Soul program, the faith community nurse involved laypersons as health ministry team members to support urban African American churchgoers in learning and practicing healthier eating and self-care practices.

Acceptance of medications for opioid use disorder in recovery housing programs in Missouri.

Background: Recovery housing plays an important role in supporting individuals in their recovery by building recovery capital and providing stable living environments; however, the extent to which medications for opioid use disorder (MOUD), the gold standard for OUD treatment, are accepted in recovery housing settings is unclear. The purpose of this study, as part of a larger statewide evaluation of Missouri recovery homes, was to identify the extent to which Missouri recovery houses were accepting of methadone, buprenorphine, and naltrexone as well as the extent to which the acceptance of each medication was linked to whether the recovery home encouraged tapering off MOUDs.

Methods: Sixty-four recovery housing managers and/or staff, out of 66 eligible recovery homes in Missouri completed the survey.

Climate variability and aridity modulate the role of leaf shelters for arthropods: A global experiment.

Current climate change is disrupting biotic interactions and eroding biodiversity worldwide. However, species sensitive to aridity, high temperatures, and climate variability might find shelter in microclimatic refuges, such as leaf rolls built by arthropods. To explore how the importance of leaf shelters for terrestrial arthropods changes with latitude, elevation, and climate, we conducted a distributed experiment comparing arthropods in leaf rolls versus control leaves across 52 sites along an 11,790 km latitudinal gradient.

Iron(II) complexes supported by pyrazolyl-substituted cyclopentadienyl ligands: synthesis and reactivity.

The preparation of bis(pyrazolyl)cyclopentadienyl iron complexes is described. Isopropyl substitution promotes solubility of the iron chloride complex that serves as a precursor to several derivatives through ligand exchange. Modification of the cyclopentadienyl substituent to replace a pyrazolyl unit with a phenyl group favors formation of a substituted ferrocene complex.

Assessing Data Completeness, Quality, and Representativeness of in the FBI's Supplementary Homicide Reports: A Research Note.

Introduction: The most widely used data set for studying police homicides-the Supplementary Homicide Reports (SHR) kept by the Federal Bureau of Investigation-is collected from a voluntary sample.

Materials And Methods: Using a journalist-curated database of police-related deaths, we find the SHR police homicide data to be substantially incomplete. This is due to both non-reporting and substantial under-reporting by agencies.

Sexual Risk Behavior among Adolescents Seeking Treatment for Posttraumatic Stress Disorder: Exploring Psychosocial & Symptom Correlates.

Adolescents exposed to trauma experience disproportionate rates of HIV/STI. However, integrated treatment for trauma and sexual risk behavior is rare. To inform integrated prevention efforts, the current study describes prevalence and correlates of sexual risk behavior among adolescents seeking treatment for symptoms of posttraumatic stress and substance use disorders.