64 results match your criteria: "University of Missouri Healthcare[Affiliation]"

Masses of the mediastinum have a wide differential diagnosis. Paragangliomas are rare neoplasms of neuroendocrine origin. These masses may be either parasympathetic or sympathetic in origin and have variable presentation.

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Article Synopsis
  • Hemophagocytic lymphohistiocytosis (HLH) is a rare and severe immune disorder that is hard to diagnose due to its varied causes and symptoms, often requiring intense medical care.
  • HLH can either be genetic (HLH syndrome) or acquired (HLH disease), triggered by instances like infections, autoimmune diseases, or cancers; this case study presents the first known instance of HLH caused by tularemia in an older female patient.
  • The patient was initially treated for suspected malignancy but switched to antimicrobial therapy after testing positive for tularemia, leading to a lengthy recovery period but ultimately highlighting the need for quick identification of triggering infections for more effective HLH treatment.
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Context: Translating new evidence into clinical practice is a dynamic and iterative process. Research is ever evolving specific to concussion rehabilitation and requires a systematic approach rooted in science for translation into clinical practice. The knowledge-to-action (KTA) cycle framework is an effective strategy to ensure optimal outcomes and sustainability.

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Aims: The aims of this study were to describe the experiences of nurses in the aftermath of the COVID-19 pandemic and to explore nurses' current desired support needs.

Design: This study used a qualitative descriptive design.

Methods: This study was conducted in the Southeastern United States at an academic health system encompassing acute care hospitals and outpatient speciality clinics.

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Article Synopsis
  • * Interviews with eight nurses revealed key themes such as chronic struggles with compassion fatigue and burnout, alongside more specific experiences of second victimhood and moral injury after traumatic events.
  • * The study emphasized the ongoing effects of these challenges, which have intensified since the pandemic, indicating an urgent need for future research and support systems to improve nurses' well-being and reduce stress in the workplace.
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I saw the "hook" sign of median arcuate ligament syndrome.

Clin Imaging

September 2024

School of Medicine, University of Missouri, Columbia, MO, United States of America; Department of Radiology, University of Missouri Healthcare, Columbia, MO, United States of America.

The hook sign is a radiologic finding best appreciated on a sagittal view of the celiac artery with computed tomography (CT) that indicates compression of the celiac artery. It refers to the hooked-shape of the proximal celiac artery caused by extrinsic compression by the median arcuate ligament. When seen in a patient with concurrent abdominal symptoms, it suggests median arcuate ligament syndrome (MALS).

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Objective: Musculoskeletal pain complaints are common in the emergency department (ED). The objective of this study was to determine the impact of physical therapy (PT) in the ED on pain and ED return.

Methods: A prospective cohort study was performed with those presenting to the ED or Urgent Care at a single academic center for musculoskeletal pain between November 2020 and December 2022.

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Purpose: The purpose of this concept delineation was to differentiate similar concepts impacting nurse well-being during the COVID-19 pandemic, including: compassion fatigue, burnout, moral injury, secondary traumatic stress, and second victim.

Methods: A total of 63 articles were reviewed for concept delineation. Morse's (1995) approach to concept delineation was utilized to analyse the articles.

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Background: The ankle is one of the anatomic sites most frequently injured in National Football League (NFL) players. Ankle injuries have previously been shown to have long-lasting negative impacts, and have been associated with impaired athletic performance. The aim of this study was to use fantasy football points as a metric to evaluate the impact of ankle injuries on NFL offensive skill player performance.

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Background: Late preterm births account for a large portion of preterm births, yet the optimal method of nutrition and enteral feeding in this population remains unclear and often involves intravenous (IV) fluids.

Purpose: To develop and implement a late preterm feeding protocol in order to decrease the necessity of IV access, decrease the use of starter parenteral nutrition (PN), and reduce the pain endured by an infant in the neonatal intensive care unit.

Methods: The Plan-Do-Study-Act quality improvement model was utilized as a framework for the implementation of this quality improvement project.

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Article Synopsis
  • - The study investigates the link between ankle injuries and the risk of concussions in NFL players, addressing a gap in existing research that could enhance player safety by focusing on musculoskeletal factors.
  • - An analysis of data from the 2009-2010 to 2019-2020 NFL seasons revealed that while a single ankle injury did not significantly increase concussion risk, multiple ankle injuries significantly raised that risk.
  • - Results indicate that special teams players have the lowest concussion risk after ankle injuries, while there was no notable difference between offensive and defensive players, suggesting potential implications for injury prevention strategies in the league.
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Little is known about COVID-19 impact on patient medication management. The aim was to describe medication management, healthcare team interactions, and adherence during the COVID-19 pandemic in kidney transplant patients and those on the kidney transplant wait list. Using a descriptive, correlational design 340 adults from a midwestern US transplant program were recruited.

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Caregiver Perceptions of an Interdisciplinary Intensive Therapy Program: A Qualitative Study.

Pediatr Phys Ther

April 2023

Department of Physical Therapy (Drs Hall, Chole, Pruitt, and Linkeman), University of Missouri, Columbia, Missouri; University of Missouri Healthcare Children's Therapy Center (Dr Chole), Columbia, Missouri.

Purpose: To explore perceptions of caregivers of children with neurodevelopmental conditions participating in an interdisciplinary intensive therapy program.

Methods: Semi-structured interviews were completed with caregivers. The intensive program consisted of occupational, physical, and/or speech therapy 3 to 6.

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Evidence-Based Guidelines for Prehospital Pain Management: Recommendations.

Prehosp Emerg Care

February 2023

Colorado Springs Fire Department, Colorado Springs, Colorado, USA.

This project sought to develop evidence-based guidelines for the administration of analgesics for moderate to severe pain by Emergency Medical Services (EMS) clinicians based on a separate, previously published, systematic review of the comparative effectiveness of analgesics in the prehospital setting prepared by the University of Connecticut Evidence-Based Practice Center for the Agency for Healthcare Research and Quality (AHRQ). A technical expert panel (TEP) was assembled consisting of subject matter experts in prehospital and emergency care, and the development of evidence-based guidelines and patient care guidelines. A series of nine "patient/population-intervention-comparison-outcome" (PICO) questions were developed based on the Key Questions identified in the AHRQ systematic review, and an additional PICO question was developed to specifically address analgesia in pediatric patients.

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Background High efficacy disease modifying therapies (DMT) in the management of Multiple Sclerosis (MS) have a favorable effect on relapse rate and disability progression; however, they can expose patients to significant risks, such as progressive multifocal leukoencephalopathy (PML). Objective The study aims to investigate prognostic factors that can determine outcome in MS-related PML patients. Methods We conducted a literature review and meta-analysis of 194 patients from 62 articles in PubMed, SCOPUS and EMBASE.

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Acute transverse myelitis with Dysautonomia following SARS-CoV-2 infection: A case report and review of literature.

J Neuroimmunol

April 2021

Department of Neurology, West Virginia University School of Medicine, Morgantown, WV, USA; West Virginia Clinical Transitional Science, Morgantown, WV, USA. Electronic address:

Article Synopsis
  • A unique case of a patient recovering from transverse myelitis and dysautonomia after a COVID-19 infection was evaluated, showcasing abnormal MRI and CSF findings.
  • The study reviews existing cases of transverse myelitis linked to COVID-19 and highlights that this is the first documented case where a patient showed both conditions post-infection.
  • The patient was treated successfully with intravenous methyl prednisone and bromocriptine, leading to complete resolution of symptoms and lesions, prompting calls for more research into the relationship between COVID-19 and neurological issues.
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A Comprehensive Systematic Review of CSF analysis that defines Neurological Manifestations of COVID-19.

Int J Infect Dis

March 2021

West Virginia Clinical and Translational Science Institute, United States; Department of Neurology, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, United States; Department of Neurology, Wayne State University, Detroit, MI, United States. Electronic address:

Background: Limited literature exists on Cerebrospinal fluid (CSF) findings in COVID-19 patients with neurological symptoms. In this review, we conducted a descriptive analysis of CSF findings in patients with COVID-19 to understand prognosis and explore therapeutic options.

Methods: We searched PubMed, Google Scholar, and Scopus databases using the keywords "SARS-CoV-2 in cerebrospinal fluid" and "SARS-CoV-2 and CNS Complications"" for reports of CSF findings in COVID-19 related neurological manifestations.

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We performed a systematic literature review of neuroimaging, predominantly focusing on magnetic resonance imaging (MRI) findings associated with neurological manifestations of coronavirus disease-2019 (COVID-19). We screened articles from PubMed, Google Scholar and Scopus, looking for reports that would potentially have neuroimaging findings in patients with COVID-19. Data analysis was performed with patient-based data based on the availability of clinical characteristics and outcomes for each individual patient from the studies.

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Guillain Barré Syndrome and its variants as a manifestation of COVID-19: A systematic review of case reports and case series.

J Neurol Sci

January 2021

Department of Neurology, Wayne State University, Detroit, MI, United States of America; Department of Biochemistry, Microbiology and Immunology, Detroit, MI, United States of America.

Background: The COVID-19 pandemic caused by SARS-COV-2 began in Wuhan, China in December 2019. Reports of COVID-19 with central (CNS) and peripheral nervous (PNS) system manifestations are emerging. In this systematic review, we compared and summarized the demographics, clinical features, Brighton criteria, immunological and laboratory findings with a focus on modified Erasmus GBS Outcome Score (mEGOS) in SARS-CoV-2 patients with GBS and its variants.

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Background: Medication nonadherence is a public health issue that contributes to poor health outcomes and health-care costs. Factors influencing long-term medication adherence are known; however, little is known about short-course medication adherence.

Objective: This study examined patient perspectives on adherence and factors that influence adherence to short-course pharmacotherapy in diarrhea-predominant irritable bowel syndrome.

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