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Introduction: This study compares recent vasopressin use and outcomes to our early practice when vasopressin was introduced for septic shock.

Methods: Charts of Surgical Intensive Care Unit (SICU) patients receiving vasopressin for septic shock in 2005-2006 (05-06 cohort,) were retrospectively reviewed. Demographics, APACHE II, hemodynamic variables, and vasoactive drug data were compared to a similar 1999-2000 cohort (99-00 cohort).

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