131 results match your criteria: "University of Michigan Cardiovascular Center[Affiliation]"
J Heart Lung Transplant
November 2024
Depatment of Cardiac Surgery, Michigan Medicine, University of Michigan Cardiovascular Center, Ann Arbor, Michigan.
Background: Patients have substantial variability in perioperative outcomes after left ventricular assist device (LVAD) implant. A perioperative multidimensional tool integrating mortality, adverse events (AEs), and patient-reported outcomes to assist in quality improvement initiatives is needed.
Methods: Patients undergoing HeartMate 3 LVAD implant (January 1, 2017 to January 31, 2024) in the Society of Thoracic Surgeons' Intermacs registry were studied.
J Thorac Cardiovasc Surg
January 2025
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pa; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pa. Electronic address:
Objective: With an aging population and advancements in imaging, recurrence of thoracic aortic dissection is becoming more common.
Methods: All patients enrolled in the International Registry of Aortic Dissection from 1996 to 2023 with type A and type B acute aortic dissection were identified. Among them, initial dissection and recurrent dissection were discerned.
J Vasc Surg
October 2023
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, MI. Electronic address:
Background: Thoracic endovascular aortic repair (TEVAR) has evolved as the standard for treating complicated acute type B aortic dissection (ATBAD). Acute kidney injury (AKI) is a common complication in critically ill patients and is commonly observed in patients with ATBAD. The purpose of the study was to characterize AKI after TEVAR.
View Article and Find Full Text PDFAm J Hypertens
August 2023
Department of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA.
Background: The effects of the renin-angiotensin-aldosterone system in cardiovascular system have been described based on small studies. The aim of this study was to evaluate the relationship between aldosterone and plasma renin activity (PRA) and cardiovascular structure and function.
Methods: We studied a random sample of Multi-Ethnic Study of Atherosclerosis participants who had aldosterone and PRA blood assays at 2003-2005 and underwent cardiac magnetic resonance at 2010.
Asian Cardiovasc Thorac Ann
February 2023
Division of Cardiac Surgery, Department of Surgery, 10033London Health Sciences Centre, London, Ontario, Canada.
Background: The optimal nadir temperature for hypothermic circulatory arrest during aortic arch surgery remains unclear. We aimed to assess and compare clinical outcomes of all three temperature strategies (deep, moderate, and mild hypothermia) using a network meta-analysis.
Methods: After literature search with MEDLINE and EMBASE through December 2021, studies comparing clinical outcomes with deep (<20°C), moderate (20-28°C), or mild (>28°C) hypothermic circulatory arrest were included.
Ann Thorac Surg
April 2023
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Department of Cardiothoracic Surgery, Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Electronic address:
Int J Cardiol
January 2023
FACT (French Alliance for Cardiovascular clinical Trials), Université de Paris, Hôpital Bichat (Assistance Publique - Hôpitaux de Paris) and INSERM U-1148, all in Paris, France; National Heart and Lung Institute, Imperial College, London, United Kingdom.
Aims: THEMIS is a double-blind, randomized trial of 19,220 patients with diabetes mellitus and stable coronary artery disease (CAD) comparing ticagrelor to placebo, in addition to aspirin. The present study aimed to describe the proportion of patients eligible and reasons for ineligibility for THEMIS within a population of patients with diabetes and CAD included in the Reduction of Atherothrombosis for Continued Health (REACH) registry.
Methods And Results: The THEMIS eligibility criteria were applied to REACH patients.
Circulation
October 2022
University of Texas Health Science Center at Houston, Houston, TX (G.S.O., E.R.T.).
Background: Hybrid debranching repair of pararenal and thoracoabdominal aortic aneurysms was initially designed as a better alternative to standard open repair, addressing the limitations of endovascular repair involving the visceral aorta. We reviewed the collective outcomes of hybrid debranching repairs using extra-anatomic, open surgical debranching of the renal-mesenteric arteries, followed by endovascular aortic stenting.
Methods: Data from patients who underwent hybrid repair in 14 North American institutions during 10 years were retrospectively reviewed.
Circ Cardiovasc Qual Outcomes
May 2022
Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora (M.P., P.M.H.).
Circ Cardiovasc Qual Outcomes
March 2022
Division of Cardiology, Section of Advanced Heart Failure, Transplantation, and Mechanical Circulatory Support, University of Colorado Anschutz Medical Campus, Aurora (P.K.).
JAMA Cardiol
March 2022
Cardiovascular Imaging Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Importance: Race and ethnicity have been studied as risk factors in cardiovascular disease. How risk factors, epicardial coronary artery disease, and cardiac events differ between Black and White individuals undergoing noninvasive testing for coronary artery disease is not known.
Objective: To assess differences in cardiovascular risk burden, coronary plaque, and major adverse cardiac events between Black and White individuals assigned to receive coronary computed tomography angiography (CCTA) or functional testing for stable chest pain.
J Heart Lung Transplant
February 2022
Henry Ford Hospitals, Detroit, Michigan. Electronic address:
Background: Preoperative variables can predict short term left ventricular assist device (LVAD) survival, but predictors of extended survival remain insufficiently characterized.
Method: Patients undergoing LVAD implant (2012-2018) in the Intermacs registry were grouped according to time on support: short-term (<1 year, n = 7,483), mid-term (MT, 1-3 years, n = 5,976) and long-term (LT, ≥3 years, n = 3,015). Landmarked hazard analyses (adjusted hazard ratio, HR) were performed to identify correlates of survival after 1 and 3 years of support.
Ann Thorac Surg
September 2020
Department of Cardiac Surgery, University of Michigan Cardiovascular Center, 1500 E Medical Center Dr, CVC5351, Ann Arbor, MI 48109.
Ann Thorac Surg
July 2020
Department of Cardiac Surgery, University of Michigan Cardiovascular Center, 1500 E Medical Center Dr, CVC5351, Ann Arbor, MI 48109. Electronic address:
Catheter Cardiovasc Interv
April 2020
University of Michigan Cardiovascular Center, Ann Arbor, Michigan.
Indian J Thorac Cardiovasc Surg
June 2019
Division of Cardiovascular Surgery, University of Pennsylvania, 3400 Spruce Street, 6 Silverstein, Philadelphia, PA 19104 USA.
With the proliferation of non-invasive thoracic imaging modalities, the question of when to operate on asymptomatic ascending aortic aneurysms for non-syndromic patients is becoming increasingly relevant. Operation is extensive, often involves circulatory arrest, and subjects the patient to significant risk of mortality and morbidity. Surgery is performed to avert fatal aortic adverse events, which carry a markedly poor prognosis.
View Article and Find Full Text PDFAnn Thorac Surg
September 2018
Department of Cardiac Surgery, University of Michigan Cardiovascular Center, 5144 Frankel Cardiovascular Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5237.
Am Heart J
March 2018
Duke Clinical Research Institute, Durham, NC. Electronic address:
Background: Assessing hospital-related network-level primary percutaneous coronary intervention (PCI) performance for ST-segment elevation myocardial infarction (STEMI) is challenging due to differential time-to-treatment metrics based on location of diagnostic electrocardiogram (ECG) for STEMI.
Methods: STEMI patients undergoing primary PCI at 588 PCI-capable hospitals in AHA Mission: Lifeline (2008-2013) were categorized by initial STEMI identification location: PCI-capable hospitals (Group 1); pre-hospital setting (Group 2); and non-PCI-capable hospitals (Group 3). Patient-specific time-to-treatment categories were converted to minutes ahead of or behind their group-specific mean; average time-to-treatment difference for all patients at a given hospital was termed comprehensive ECG-to-device time.
Ann Thorac Surg
February 2018
Department of Cardiac Surgery, University of Michigan Cardiovascular Center, 5144 Frankel Cardiovascular Center, 1500 E Medical Center Dr, Ann Arbor, MI 48109-5237.
Eur Heart J
March 2018
University of Michigan Cardiovascular Center, 24 Frank Lloyd Wright Dr, Ann Arbor, MI 48105, USA.
Acute aortic syndromes (AAS) encompass a constellation of life-threatening medical conditions including classic acute aortic dissection (AAD), intramural haematoma, and penetrating atherosclerotic aortic ulcer. Given the non-specific symptoms and physical signs, a high clinical index of suspicion is necessary to detect the disease before irreversible lethal complications occur. In order to reduce the diagnostic time delay, a comprehensive flowchart for decision-making based on pre-test sensitivity of AAS has been designed by the European Society of Cardiology guidelines on aortic diseases and should be thus applied in the emergency scenario.
View Article and Find Full Text PDFJ Invasive Cardiol
October 2017
University of Michigan Cardiovascular Center, 2A 394, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5853 USA.
Objectives: We sought to describe trends in the use of preprocedural P2Y12 inhibitors and their clinical impact in patients undergoing percutaneous coronary intervention (PCI).
Background: Oral P2Y12 inhibitors are ubiquitously used medications; however, the specific timing of initial P2Y12 inhibitor administration remains intensely debated.
Methods: Our study population comprised 74,053 consecutive patients undergoing PCI at 47 hospitals in Michigan from January 2013 through June 2015.
J Am Heart Assoc
April 2017
Durham VA Medical Center, Durham, NC.
Background: Patients with chronic kidney disease (CKD) are at increased risk for bleeding, transfusion, and dialysis after cardiac catheterization. Whether rates of these complications are increased in this high-risk population undergoing transradial access compared with transfemoral access is unknown.
Methods And Results: From the Veterans Affairs (VA) Clinical Assessment Reporting and Tracking program, we identified 229 108 patients undergoing cardiac catheterization between 2007 and 2014, of which 48 155 (21.
Ann Vasc Surg
July 2017
Section of Vascular Surgery, University of Michigan Cardiovascular Center, Ann Arbor, MI. Electronic address:
Background: Iatrogenic femoral artery trauma complicates the course of critically ill neonates and children. Complications from persistent arterial occlusion may include claudication and limb length discrepancies. Data supporting risk factors for such and need for revascularization are lacking.
View Article and Find Full Text PDFFront Immunol
February 2017
Department of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, MI, USA; Cardiovascular Research Institute, Wayne State University School of Medicine, Detroit, MI, USA.
On the basis of mouse I-A-binding motifs, two sequences of the murine apolipoprotein B-100 (mApoB-100), mApoB-100 (designated P3) and mApoB-100 (designated P6), were found to be immunogenic. In this report, we show that P6 is also atherogenic. Immunization of mice fed a high-fat diet (HFD) with P6 resulted in enhanced development of aortic atheroma as compared to control mice immunized with an irrelevant peptide MOG or with complete Freund's adjuvant alone.
View Article and Find Full Text PDFAnn Thorac Surg
June 2017
Department of Cardiac Surgery, University of Michigan Cardiovascular Center, Ann Arbor, Michigan.
Valvular regurgitation is a recognized complication of aortic and mitral valve procedures, with paravalvular leak the primary mechanism and transvalvular leak less common. The Cor-Knot automated fastener (LSI Solutions, Victor, NY) has been shown to be a safe, viable alternative to knot pushers or manual tying for use in these procedures. Here we present two patients in whom the orientation of the Cor-Knot fastener appeared to result in transvalvular regurgitation necessitating a redo operation.
View Article and Find Full Text PDF