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Seizure Duration and Spread Dynamics in MRI-Defined Subtypes of Temporal Lobe Epilepsy.
Neurology
July 2022
From the Departments of Neurology (V.J.W.Z., G.D.J., D.N.V.) and Radiology (G.F., Y.P.), Austin Hospital, Heidelberg; and Florey Institute of Neuroscience and Mental Health (V.J.W.Z., G.D.J., D.N.V.), University of Melbourne (G.F., Y.P.), Parkville, Victoria, Australia.
Background And Objectives: MRI and PET imaging enables subgroups of temporal lobe epilepsy (TLE) to be defined on the basis of structural pathology. Few studies have examined the variation in electroclinical seizure spread patterns based on imaging findings. We performed a retrospective cohort study to investigate the electroclinical differences among 3 specific groups of TLE: MRI-negative PET-positive TLE (MRI-negative TLE), temporal lobe lesion TLE (lesional TLE), and unilateral hippocampal sclerosis TLE (HS-TLE).
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