Spectrometric determination of total antioxidant activity in chlorpromazine radical cation - ascorbic acid system.

Unlabelled: Through univalent oxidation chlorpromazine forms a colored and relatively stable radical cation with maximum absorbance at 525 nm, considered a redox mediator in a number of b iochemical reactions.

Aim: To develop a spectrometric method for the determination of total antioxidant activity based on the reaction of chlorpromazine radical capture by ascorbic acid (standard antioxidant).

Material And Methods: The calibration curve was drawn by monitoring the decrease in the absorbance of the preformed radical solution (obtained by oxidation of chlorpromazine by potassium persulfate in an acidic environment) depending on ascorbic acid concentration.

Occupational health problems among dentists in Moldavian Region of Romania.

Aim: The aim of this study was to evaluate the occupational health problems among dentists in the Moldavian Region of Romania.

Material And Methods: Questionnaire-based study was conducted on 152 dentists aged between 25-65 years practicing in 6 counties the Moldavian Region of Romania. The questionnaire included questions related to the dentists' occupational health pathology.

Variables of job satisfaction in medical assistant profession.

Aim: To identify the key favorable issues, showing a high degree of job satisfaction, and also the adverse issues that may affect the work performance among medical assistants.

Material And Methods: This research is a type of inquiry-based opinion survey carried out by administering a self-managed, anonymous questionnaire, consisting of five sections with 25 items. The study group included 175 medical assistants from all specialties, working in public hospitals in the city of Iasi, who answered the questionnaires.

Assessment of nutritional habits on a group of pupils from a countryside elementary school in Romania.

Unlabelled: Food is a major contributor to healthy children and youth. The study of this factor must be complex, considering the dietary habits of the population.

Material And Methods: 65 pupils from rural area were surveyed weekly about eating chicken, fish, fruits, bread and cereal by-products.

Some observations on the optimization of pre-hospital emergency medical services from the city of Iasi, Romania.

Unlabelled: In the lasi City, with a population of 825,100 inhabitants, the number of requests for ambulance service has increased steadily for the past 17 years. One of the determining factors could be the development of the primary health care prevention.

Material And Methods: We take into study some factors which consider influencing the reorganization of emergency medical systems in the lasi City territory.

Clinical and epidemiological study on the prevalence of rheumatoid arthritis in some demographic structures.

Unlabelled: The structure of the epidemiological process of rheumatoid arthritis (RA) is integrated in a broader framework of multiple interactions between intrinsic predisposing factors and the external environmental factors that may have a triggering or stimulating effect. The summative phenom enon is the result of the additive effect of risk factors, the individualized response of body structures and functions, depending on the genetic makeup explain the complexity of the epidemiologic study.

Aim: To evaluate the epidemiological, clinical and biological features of a series of RA patients.

Inverted duplication deletion of 8P: characterization by standard cytogenetic and SNP array analyses.

Inverted 8p duplication deletions are recurrent chromosomal rearrangements that most often arise through non-allelic homologous recombination (NAHR) during maternal meiosis between segmental duplications made up of the olfactory receptor (OR) gene clusters. The presence of a paracentric inversion polymorphism in 8p23.1, found in approximately 26% of European population, may trigger meiotic misalignment and NAHR between the OR gene repeats.

Genotype- phenotype correlation in trisomy X: a retrospective study of a selected group of 36 patients and review of literature.

Unlabelled: Trisomy X (47,XXX) is a gonosomal aneuploidy characterized by the presence of an extra X chromosome in a female person. Usually the diagnosis is established made postnatally by chromosome analysis in patients with suggestive clinical signs. Clinical signs vary by age.

Ebstein's anomaly.

Ebstein's anomaly is a rare congenital heart disease, accounting for less than 1% of all congenital heart diseases, characterized by a wide clinical, electrocardiographic, echocardiographic, anatomic and prognostic polymorphism. The disease can be fatal since birth or may remain asymptomatic until adulthood, sometimes being associated with septal defects, transposition of great vessels, preexcitation syndromes, or left ventricular noncompaction. The genetic changes underlying this syndrome are not fully known, but in the cases associating left ventricular nonompaction a mutation in MYH7 gene encoding the beta-myosin heavy chain was recently detected.

Heart rate variations in chronic obstructive pulmonary disease.

Unlabelled: Autonomic nervous system dysfunction proved in chronic obstructive pulmonary disease (COPD) patients might determine an elevated cardiovascular risk by heart rate alteration.

Aim: To assess the particularities of heart rate as a possible cardiovascular risk factor in COPD patients.

Materials And Methods: This prospective, case-control study comparatively analyzed the pulse rate continuously recorded with a polygraph in 32 COPD patients and 29 healthy subjects during rest (supine and sitting position) and during submaximal exercise (6-minute walk test).

The assessment of treatment efficacy in age related macular degeneration by evaluating the oxidative stress markers and OCT measurements.

Unlabelled: Age related macular degeneration (AMD) is the most frequent cause of blindness in the elderly.

Aim: To establish the role of oxidative stress in retinal structural lesions in AMD and to monitor the evolution of oxidative stress markers and OCT measurements before and after treatment.

Material And Methods: This is a case-control study that included 19 patients diagnosed with AMD and 40 matched healthy controls.

Plant-derived anticancer agents - curcumin in cancer prevention and treatment.

Nowadays cancer is still a major public health issue. Despite all the progresses made in cancer prevention, diagnosis and treatment, mortality by cancer is on the second place after the one caused by cardiovascular diseases. The high mortality and the increasing incidence of certain cancers (lung, prostate, colorectal) justify a growing interest for the identification of new pharmacological agents efficient in cancer prevention and treatment.

Spectrometric method for the assay of ramipril using molybdophosphoric acid.

Unlabelled: Ramipril is a drug of the angiotensin converting enzyme inhibitor class.

Aim: A new molecular absorbance spectrometric method was developed for the assay of ramipril using molybdophosphoric acid in acidic medium.

Material And Methods: The reaction product showed a maximum absorbance at 361 nm.

Preventive attitudes towards infection transmission in dental offices in North-East Romania.

Aim: The aim of this study was to evaluate the level of knowledge and the current attitudes towards infection control in the dental offices in the Northeast Romania.

Material And Methods: Questionnaire-based study conducted on 152 dentists aged between 25-65 years practicing in 6 Northeast Romania counties. The questionnaire included questions related to current infection control procedures and attitudes.

Proprosthetic interventions in the posterior maxillary implant therapy.

Aim: The purpose of this study is to evaluate the necessary number of pro-prosthetic interventions in view of the implanto-prosthetic rehabilitation of the defective prosthetic fields.

Materials And Methods: We investigated a lot that included 230 patients aged between 18 and 82 who benefited from implant-prosthetic rehabilitation, the type of graft used, the types of membranes selected as well as the various remodeling and elevation techniques at the maxillary level dictated by the particularity of the clinical case.

Results And Discussions: The edentulous posterior maxillary region presents in implantology a more difficult situation than any other region of the maxillary.

Südeck's post-traumatic osteodystrophy.

The diversity that exists in the types of trauma, in the investigated anatomical structures, in the sites of trauma, in the outcomes of traumatic injuries, and in the general reaction of the body lead to a symptomatological polymorphism of post-traumatic sequelae. Therefore it is impossible to establish a well-defined nosological entity of these sequelae. The damaged tissues react under a very similar scheme, irrespective of the type of tissue, trauma or area, namely, through an inflammatory process, that causes various sequelae depending on certain parameters.

Colon cancer at the molecular level--usefulness of epithelial-mesenchymal transition analysis.

Colorectal cancer (CRC) is the third form of cancer in both men and women. In Romania, the incidence of CRC in 2000 is 17.74 %ooo, in 2002 becoming the second cause of death.

Surgical-orthodontic treatment of malocclusions through Begg technique.

Aim: To assess the effectiveness and quality of surgical-orthodontic treatment outcomes through Begg technique in patients with malocclusions.

Material And Methods: Of a total of 117 patients referred to the Orthodontics Clinic lasi, 16 patients with malocclusions (7 boys and 9 girls) were selected according to certain criteria and received surgical and orthodontic treatment through Begg technique. The outcomes were assessed clinically and radiological.

Management of borderline ovarian tumors.

Unlabelled: Borderline ovarian tumors are an intermediate stage between benign cystadenomas and adenocarcinomas.

Aim: The paper evaluates the management of borderline ovarian tumors (BOTs) in the patients admitted and treated in our clinic in the interval January 2003 - June 2011.

Material And Methods: The observation sheets and pathology results of 264 patients with malignant ovarian tumors were analyzed.

Cervical incompetence associated with congenital uterine malformations.

Unlabelled: Cervical incompetence is basically a cervix that is too weak to stay closed during a pregnancy. It is generally categorized as premature opening of the cervix without labor or contractions.

Aim: To estimate the incidence of incompetence of the uterine cervix at patients with congenital uterine malformations.

Efficacy of rifaximin versus lactulose for reducing the recurrence of overt hepatic encephalopathy and hopitalizations in cirrhosis.

Unlabelled: Both rifaximin and lactulose have been reported to be effective for maintenance of remission from hepatic encephalopathy (HE) in patients with cirrhosis. The aim of this study was to compare the efficacy of different treatment strategies for preventing recurrences and HE-related hospitalizations.

Materials And Methods: Seventy-eight cirrhotic patients who recovered from HE were grouped according to one of the following therapies: rifaximin intermittently 14 days/month (RI- group), rifaximin 400 mg three times daily (RD-group) and lactulose 30 to 60 ml in 2 or 3 divided doses daily (L-group) for a 6-month period.

Myasthenia gravis associated with thymoma and toxic multinodular goiter. A case report.

Adequate antithyroid drug treatment or surgery usually generates remission of myasthenia gravis (MG) in patients with thymus hyperplasia associated with Graves' hyperthyroidism. The case of a 46-year-old woman diagnosed with MG based on the clinical picture, anticholinesterase drug test and positive electromyography (EMG) is presented. The cervico-thoracic computer tomography revealed a compressive nodular goiter and normal antero-superior mediastinum and led to the diagnosis of MG secondary to the hyperthyroidism.

The central role of the non alcoholic fatty liver disease in metabolic syndrome.

Non-alcoholic fatty liver disease (NAFLD) covers a spectrum of liver disease from steatosis to non-alcoholic steatohepatitis (NASH) and cirrhosis. Most NAFLD patients are hyperinsulinaemic and more insulin resistant compared with nonsteatotic healthy subjects, and there is a near universal association between NAFLD and insulinresistance (IR) irrespective of obesity. The metabolic syndrome (MS) is highly prevalent in the general adult population (approximatively 22%) and it carries an increased cardiovascular morbidity and mortality.