1,030 results match your criteria: "University of Massachusetts Dartmouth.[Affiliation]"

Cranberry consumption has numerous health benefits, with experimental reports showing its anti-inflammatory and anti-tumor properties. Importantly, microbiome research has demonstrated that the gastrointestinal bacterial community modulates host immunity, raising the question of whether the cranberry-derived effect may be related to its ability to modulate the microbiome. Only a few studies have investigated the effect of cranberry products on the microbiome to date.

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Background: Exam wrapper, a structured self-regulated learning strategy, assists students to review study habits and performance on an exam with the goal of improving future study habits. Little is known about the use of this strategy in nursing students, particularly associate degree students.

Objectives: To describe and compare demographic characteristics, study habits, reasons for getting content wrong on an exam and future study plans between associate degree and baccalaureate nursing students.

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The solid-state structures of the synthetic psychedelic 5-meth-oxy-,-di--propyl-tryptamine (5-MeO-DPT) {systematic name: -[2-(5-meth-oxy-1-indol-3-yl)eth-yl]--propyl-propan-1-amine}, CHNO, and its fumarate salt, bis-(5-meth-oxy-,-di--propyl-tryptammonium) fumarate (systematic name: bis-{-[2-(5-meth-oxy-1-indol-3-yl)eth-yl]--propyl-propan-1-aminium} but-2-ene-dio-ate), 2CHNO·CHO , are reported. The freebase has a single tryptamine mol-ecule in the asymmetric unit. The mol-ecules are linked together by N-H⋯N hydrogen bonds in zigzag chains along the [010] direction.

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Botulinum neurotoxin inhibitor binding dynamics and kinetics relevant for drug design.

Biochim Biophys Acta Gen Subj

September 2021

Botulinum Research Center, Institute of Advanced Sciences, Dartmouth, MA, USA; Department of Chemistry and Biochemistry, University of Massachusetts Dartmouth, North Dartmouth, MA, USA; Prime Bio Inc., Dartmouth, MA, USA. Electronic address:

Background: A natural product analog, 3-(4-nitrophenyl)-7H-furo[3,2-g]chromen-7-one, which is a nitrophenyl psoralen (NPP) was found to be an effective inhibitor of botulinum neurotoxin type A (BoNT/A).

Methods: In this work, we performed enzyme inhibition kinetics and employed biochemical techniques such as isothermal calorimetry (ITC) and fluorescence spectroscopy as well as molecular modeling to examine the kinetics and binding mechanism of NPP inhibitor with BoNT/A LC.

Results: Studies of inhibition mechanism and binding dynamics of NPP to BoNT/A light chain (BoNT/A LC) showed that NPP is a mixed type inhibitor for the zinc endopeptidase activity, implying that at least part of the inhibitor-enzyme binding site may be different from the substrate-enzyme binding site.

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Understanding how anthropogenic disturbances affect plant-pollinator systems has important implications for the conservation of biodiversity and ecosystem functioning. Previous laboratory studies show that pesticides and pathogens, which have been implicated in the rapid global decline of pollinators over recent years, can impair behavioral processes needed for pollinators to adaptively exploit floral resources and effectively transfer pollen among plants. However, the potential for these sublethal stressor effects on pollinator-plant interactions at the individual level to scale up into changes to the dynamics of wild plant and pollinator populations at the system level remains unclear.

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The sex pheromone system of ~160,000 moth species acts as a powerful form of assortative mating whereby females attract conspecific males with a species-specific blend of volatile compounds. Understanding how female pheromone production and male preference coevolve to produce this diversity requires knowledge of the genes underlying change in both traits. In the European corn borer moth, pheromone blend variation is controlled by two alleles of an autosomal fatty-acyl reductase gene expressed in the female pheromone gland (pgFAR).

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Use of Exam Wrapper Metacognitive Strategy to Promote Student Self-assessment of Learning: An Integrative Review.

Nurse Educ

December 2021

Author Affiliations: Professor (Dr Sethares), Department of Adult Nursing, University of Massachusetts Dartmouth; and Adjunct Associate Professor (Dr Asselin), College of Nursing, University of Rhode Island, Kingston.

Background: Metacognitive knowledge and regulation are critical to nursing students who must apply knowledge to rapidly changing and complex conditions. Exam wrappers assist learners to consider past study habits with the goal of improving future exam preparation. However, little is known about use of exam wrappers in nursing education.

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Background: Delayed Dark-Adapted vision Recovery (DAR) is a biomarker for Age-related Macular Degeneration (AMD), however its measurement is burdensome for patients and examiners.

Methods: In this study, we developed a portable, wireless and user-friendly system that employs a headset with a smartphone to deliver controlled photo-bleach and monocular pattern reversal stimuli, while using custom electroencephalography (EEG) electrodes and electronics in order to measure Dark-Adapted Visual Evoked Potentials (DAVEP) objectively and separately at the peripheral and central visual field. This is achieved in one comfortable 20-minute session, without requiring subject reporting.

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A focus group methodology was employed to elicit information from Certified Nursing Assistants (CNAs) about their views of the personality, social, institutional and cultural factors that affect the success or failure of elders' adaptation to nursing home life. The focus group (N = 6) was conducted in one long-term care facility. CNAs identified three themes that represent the process of successful adaptation to the nursing home.

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The title compound, bis-(,-diallyl-5-meth-oxy-tryptammonium) (5-MeO-DALT) fumarate (systematic name: bis-{-[2-(5-meth-oxy-1-indol-3-yl)eth-yl]- -(prop-2-en-1-yl)prop-2-en-1-aminium} ()-but-2-enedioate), 2CHNO·CHO , has a single tryptammonium cation and half of a fumarate dianion in the asymmetric unit. The tryptammonium and fumarate ions are held together in one-dimensional chains by a series of N-H⋯O hydrogen bonds. These chains are combinations of (22) rings, and (14) and (28) parallel chains along [111].

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Nursing Documentation Variation Across Different Medical Facilities Within an Integrated Healthcare System.

Comput Inform Nurs

May 2021

Author Affiliations: College of Nursing, The Catholic University of Korea, Seoul, Republic of Korea (Dr Kang); Division of General Internal Medicine and Primary Care, Brigham & Women's Hospital, Boston, MA (Mr Chang, Dr Schnock, Mr Garcia, and Dr Dykes); Harvard Medical School, Boston, MA (Dr Schnock, and Dr Dykes); School of Nursing (Dr Rossetti, Mr Knaplund, and Dr Cato) and Department of Biomedical Informatics (Dr Rossetti), Columbia University, New York, NY; Massachusetts General Hospital, Boston, MA (Ms Whalen); University of Massachusetts-Dartmouth, College of Nursing and Health Sciences, Department of Community Nursing, North Dartmouth, MA (Dr Gesner).

The purpose of this study was to demonstrate nursing documentation variation based on electronic health record design and its relationship with different levels of care by reviewing how various flowsheet measures, within the same electronic health record across an integrated healthcare system, are documented in different types of medical facilities. Flowsheet data with information on patients who were admitted to academic medical centers, community hospitals, and rehabilitation centers were used to calculate the frequency of flowsheet entries documented. We then compared the distinct flowsheet measures documented in five flowsheet templates across the different facilities.

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Elevated glucocorticoids during gestation suggest sex-specific effects on offspring telomere lengths in a wild lizard.

Comp Biochem Physiol A Mol Integr Physiol

July 2021

Department of Biology, The Pennsylvania State University, Mueller Laboratory, University Park, PA 16802, United States of America; Intercollege Graduate Degree Program in Ecology, The Pennsylvania State University, University Park, PA 16802, United States of America.

Article Synopsis
  • Maternal glucocorticoids, like corticosterone (CORT), may affect offspring health and fitness, especially in response to environmental stressors, but their impact on offspring telomere length is not well understood.
  • Using a modified PCR method, researchers studied the telomere length of eastern fence lizard offspring after treating pregnant females with CORT during gestation.
  • Results showed that although maternal CORT treatment did not change maternal telomere length, there was a potential trend of shortened telomeres in male offspring, indicating a need for further investigation into the long-term effects of maternal stress.
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In this study, we report the synthesis of self-assembled dityrosine nanotubes as a biologically functional scaffold and their interactions with neural cells. Quantum chemical methods were used to determine the forces involved in the self-assembly process. The physicochemical properties of the nanostructures relevant to their potential as bioactive scaffolds were characterized.

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It is well established that sea turtles are vulnerable to atmospheric and oceanographic shifts associated with climate change. However, few studies have formally projected how their seasonal marine habitat may shift in response to warming ocean temperatures. Here we used a high-resolution global climate model and a large satellite tagging dataset to project changes in the future distribution of suitable thermal habitat for loggerheads along the northeastern continental shelf of the United States.

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In Shark Bay, Western Australia, male bottlenose dolphins form a complex nested alliance hierarchy. At the first level, pairs or trios of unrelated males cooperate to herd individual females. Multiple first-order alliances cooperate in teams (second-order alliances) in the pursuit and defence of females, and multiple teams also work together (third-order alliances).

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High Structural Stability of Photonic Crystals on Textile Substrates, Prepared a Surface-Supported Curing Strategy.

ACS Appl Mater Interfaces

April 2021

Engineering Research Centre for Eco-Dyeing and Finishing of Textiles, Ministry of Education, Zhejiang Sci-Tech University, Hangzhou 310018, China.

Over the past years, photonic crystals (PCs) with a periodically ordered nanostructure have attracted great attention due to their potential as advanced optical materials for structural coloration of textiles. However, the weak structural stability of PCs on flexible textile substrates makes them vulnerable to strong external forces, hampering their large-scale application. In this work, a waterborne polyurethane (wPU) is chosen for enhancing the structural stability of PCs.

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Cardiac responses to appetitive stimuli have been studied as indices of motivational states and attentional processes, the former being associated with cardiac acceleration and latter deceleration. Very few studies have examined heart rate changes in appetitive classical conditioning in humans. The current study describes the development and pilot testing of a classical conditioning task to assess cardiac responses to appetitive stimuli and cues that reliably precede them.

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This study explored gender differences in competition within friendships of emerging adults. In a sample of 118 same and cross-gender friendship dyads, we used a quasi-experimental design to examine how people competed with friends and reacted to this competition when completing a task in both competitive and noncompetitive conditions. Using an Actor-Partner Interdependence Modeling approach to data analyses, we found that in the noncompetitive condition, men and women competed more with same-gender than with cross-gender friends.

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Nursing Student Perceptions of Academic and Clinical Integrity.

Nurs Educ Perspect

June 2021

About the Authors Christine Ann Devine, PhD, RN, an assistant professor in the Department of Nursing, Fitchburg State University, Fitchburg, Massachusetts, was a doctoral student at the University of Massachusetts Dartmouth, Dartmouth, Massachusetts, when this research was conducted. Elizabeth Danells Chin, PhD, RN, is an associate professor, Department of Adult Nursing, University of Massachusetts Dartmouth. Kristen A. Sethares, PhD, RN, CNE, FAHA, FHFSA, is a professor, Department of Adult Nursing, University of Massachusetts Dartmouth. Marilyn E Asselin, PhD, RN, is an adjunct associate professor, College of Nursing, University of Rhode Island, Kingston, Rhode Island. Dr. Devine was a recipient of the National League for Nursing/Eastern Nursing Research Society Doctoral Research Award and a Sigma Theta Tau Iota Phi-at-Large Chapter PhD Dissertation Research Award. This research study was funded by these two awards. For more information, contact Dr. Devine at

Aim: This study aimed to explore how nursing students define and describe academic and clinical integrity and to identify social and psychological influences on student decisions to act with integrity.

Backgroud: Nursing students are exhibiting a decline in academic and clinical integrity. Academic dishonesty often correlates to clinical dishonesty, subsequently impacting patient care quality and safety.

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Article Synopsis
  • A new method has been developed to synthesize a type of compound called C-ring substituted angular luotonins using a straightforward one-pot reaction involving specific chemicals.
  • Research on these compounds showed they inhibit an enzyme called topoisomerase I (topo-I), but they are weaker inhibitors than camptothecin, a known drug.
  • Interestingly, a different type of compound called tricyclic vasicinones was found to be more effective at inhibiting topo-I than the angular luotonins, suggesting potential for further study and development as new drugs.
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An integral component of transitioning to the nursing practice setting is in assimilating and sometimes reformulating and reconceptualizing the knowledge gained in the classroom with what is seen and experienced in practice. An inability to do so may inhibit role development and result in difficult transitions to practice. A constructivist approach was utilized in the development of a new model that describes the process of learning and role development in the clinical and simulation setting.

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Nanomechanics of antimonene allotropes under tensile loading.

Phys Chem Chem Phys

March 2021

Department of Mechanical Engineering, Wayne State University, 5050 Anthony Wayne Drive, Detroit, MI-48202, USA.

Monolayer antimonene has drawn the attention of research communities due to its promising physical properties. However, the mechanical properties of antimonene have remained largely unexplored. In this work, we investigate the mechanical properties and fracture mechanisms of two stable phases of monolayer antimonene - β-antimonene (puckered structure) and α-antimonene (buckled structure) - through molecular dynamics (MD) simulations.

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Rationale: Nitrogen isotopic compositions (δ N) of source and trophic amino acids (AAs) are crucial tracers of N sources and trophic enrichments in diverse fields, including archeology, astrobiochemistry, ecology, oceanography, and paleo-sciences. The current analytical technique using gas chromatography-combustion-isotope ratio mass spectrometry (GC/C/IRMS) requires derivatization, which is not compatible with some key AAs. Another approach using high-performance liquid chromatography-elemental analyzer-IRMS (HPLC/EA/IRMS) may experience coelution issues with other compounds in certain types of samples, and the highly sensitive nano-EA/IRMS instrumentations are not widely available.

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Wearable biosensors, as a key component of wireless body area network (WBAN) systems, have extended the ability of health care providers to achieve continuous health monitoring. Prior research has shown the ability of externally placed, non-invasive sensors combined with machine learning algorithms to detect intoxication from a variety of substances. Such approaches have also shown limitations.

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