Climate resilience and profitability thresholds in Chesapeake Bay oyster aquaculture.

Shellfish aquaculture producers in coastal systems are facing uncertain future growing conditions as climate change alters weather patterns and raises sea level. We examined expected mid-century (2059-2068) changes in aquaculture profitability from recent conditions by integrating models of climate change, estuarine hydrodynamics and biogeochemistry, oyster growth, oyster mortality, and economics, using the Chesapeake Bay, USA as a case study. We developed an economic stochastic dynamic programming (SDP) approach that generates optimal grower behavior to maximize profits under uncertainty by dynamically choosing planting density, replanting and mitigation use, in response to changing oyster stock status and water quality conditions.

Soybean genomics research community strategic plan: A vision for 2024-2028.

This strategic plan summarizes the major accomplishments achieved in the last quinquennial by the soybean [Glycine max (L.) Merr.] genetics and genomics research community and outlines key priorities for the next 5 years (2024-2028).

Invasive Fungal Diseases of Combat Wounds: Burden, Epidemiology, and Mycology.

During the last two decades, wound invasive fungal diseases (WIFDs) have reemerged as important causes of mortality and morbidity in military personnel and civilian casualties in war areas. Historically, mycotic infections acquired in combat operations during Vietnam War and were associated with burn wounds. Modern combat related WIFDs are almost exclusively associated with severe traumatic events which encompass blast exposure as the primary mechanism of injury and subsequent extremity amputation and extensive blood loss.

Dissolved oxygen criteria attainment in Chesapeake Bay: Where has it improved since 1985?

Many estuaries, including Chesapeake Bay, have suffered from undesirable conditions of algae blooms, poor water clarity, and low dissolved oxygen (DO). To better understand the status and trends of DO criteria attainment deficit (AD), we conducted a comprehensive assessment using monitoring data in the period of 1985-2022 and focused on the comparison of trends among 13 tidal systems. Our results provide timely and updated information to help address a critical management question, i.

Enhancing prediction accuracy of grain yield in wheat lines adapted to the southeastern United States through multivariate and multi-environment genomic prediction models incorporating spectral and thermal information.

Enhancing predictive modeling accuracy in wheat (Triticum aestivum) breeding through the integration of high-throughput phenotyping (HTP) data with genomic information is crucial for maximizing genetic gain. In this study, spanning four locations in the southeastern United States over 3 years, models to predict grain yield (GY) were investigated through different cross-validation approaches. The results demonstrate the superiority of multivariate comprehensive models that incorporate both genomic and HTP data, particularly in accurately predicting GY across diverse locations and years.

Individual Versus Combined Effects of Warming, Elevated CO and Drought on Grassland Water Uptake and Fine Root Traits.

Increasing warming, atmospheric CO and drought are expected to change the water dynamics of terrestrial ecosystems. Yet, limited knowledge exists about how the interactive effects of these factors will affect grassland water uptake, and whether adaptations in fine root production and traits will alter water uptake capacity. In a managed C grassland, we tested the individual and combined effects of warming (+3°C), elevated CO (eCO; +300 ppm) and drought on root water uptake (RWU) as well as on fine root production, trait adaptation, and fine root-to-shoot production ratios, and their relationships with RWU capacity.

Interactions between glucagon like peptide 1 (GLP-1) and estrogens regulates lipid metabolism.

Obesity, characterized by excessive fat accumulation in white adipose tissue (WAT), is linked to numerous health issues, including insulin resistance (IR), and type 2 diabetes mellitus (DM2). The distribution of adipose tissue differs by sex, with men typically exhibiting android adiposity and pre-menopausal women displaying gynecoid adiposity. After menopause, women have an increased risk of developing android-type obesity, IR, and DM2.

Identifying the geographic leading edge of Lyme disease in the United States with internet searches: A spatiotemporal analysis of Google Health Trends data.

Background: The geographic footprint of Lyme disease is expanding in the United States, which calls for novel methods to identify emerging endemic areas. The ubiquity of internet use coupled with the dominance of Google's search engine makes Google user search data a compelling data source for epidemiological research.

Objective: We evaluated the potential of Google Health Trends to track spatiotemporal patterns in Lyme disease and identify the leading edge of disease risk in the United States.

Ambient air pollution and hospital admission for interstitial lung diseases: A multicenter hospital-based case-crossover study.

Interstitial lung diseases (ILDs) lead to increased morbidity and premature deaths, imposing a significant burden on public health worldwide. Recently, several studies have linked ambient air pollution with the acute exacerbation of certain ILDs, but the evidence remains limited and inconclusive. With a multicenter hospital-based case-crossover design, we investigated 9128 patients who resided in Jiangsu province, China, and were admitted for ILDs between 2019 and 2022.

Stress tests and biomarkers of resilience: Proceedings of the second state of resilience science conference.

The "Stress Tests and Biomarkers of Resilience" conference, hosted by the American Geriatrics Society and the National Institute on Aging, marks the second in a series aimed at advancing the field of resilience science. Held on March 4-5, 2024, in Bethesda, Maryland, this conference built upon the foundational work from the first conference, which focused on defining resilience across various domains-physical, cognitive, and psychosocial. This year's gathering centered around three factors: the biology that underlies resilient outcomes; the social, environmental, genetic, and psychosocial factors that impact that resilience biology; and the biomarker testing and imaging that predicts resilient outcomes for older adults.

Regional fire-greening positive feedback loops in Alaskan Arctic tundra.

Arctic tundra has experienced rapid warming, outpacing global averages, leading to significant greening whose primary drivers include widespread shrubification. Here we confirm that a fire-greening positive feedback loop is evident across the Alaskan tundra, and evidence suggests that this feedback loop is dominated by the fire-shrub interactions. We show that tundra wildfires, especially those with higher severity, play a critical role in boosting the overall greening of the tundra, often by enhancing upright deciduous shrub growth or establishment but sometimes by inducing increases in other vascular biomass.

Anti-Sp4 and Anti-CCAR1 autoantibodies in UK vs. US patients with adult and juvenile-onset anti-TIF1Æ´-positive myositis.

Objectives: Anti-TIF1γ autoantibodies are associated with malignancy in adult-onset idiopathic inflammatory myopathy (IIM) and this risk is attenuated if patients are also positive for anti-specificity protein 4 (Sp4) or anti-cell division cycle apoptosis regulator protein 1 (CCAR1). In anti-TIF1γ positive US dermatomyositis (DM) patients, anti-Sp4 and anti-CCAR1 autoantibody frequencies are reported as 32% and 43% in adults and 9% and 19% in juveniles, respectively. This study aims to identify the frequency of anti-Sp4 and anti-CCAR1 in adult and juvenile UK anti-TIF1ƴ-positive myositis populations and report clinical associations.

Underappreciated roles of soil nitrogen oxide emissions on global acute health burden.

The recognized importance of ambient fine particulate matter (PM), ozone (O), and nitrogen dioxide (NO) on human health has prompted the world to enact increasingly strict regulations on anthropogenic nitrogen oxides (NO) emissions. However, the health concerns from soil NO, potentially driven by fertilizer input but conventionally categorized as natural sources, remain less studied. Here, we emphasize the underappreciated roles of soil NO emissions on health burden attributable to short-term PM, O, and NO exposure.

Resistance of Boron Nitride Nanotubes to Radiation-Induced Oxidation.

We present unprecedented results on the damage thresholds and pathways for boron nitride nanotubes (BNNT) under the influence of energetic electrons in an oxidative gas environment, using an environmental aberration-corrected electron microscope over a range of oxygen pressures. We observe a damage cascade process that resists damage until a higher electron dose, compared with carbon nanotubes, initiating at defect-free BNNT sidewalls and proceeding through the conversion from crystalline nanotubes to amorphous boron nitride (BN), resisting oxidation throughout. We compare with prior results on the oxidation of carbon nanotubes and present a model that attributes the onset of damage in both cases to a physisorbed oxygen layer that reduces the threshold for damage onset.

Submesoscales are a significant turbulence source in global ocean surface boundary layer.

The turbulent ocean surface boundary layer is a key part of the climate system affecting both the energy and carbon cycles. Accurately simulating the boundary layer is critical in improving climate model performance, which deeply relies on our understanding of the turbulence in the boundary layer. Turbulent energy sources in the boundary layer are traditionally believed to be dominated by waves, winds and convection.

Precision Cut Lung Slices: Emerging Tools for Preclinical and Translational Lung Research. An Official American Thoracic Society Workshop Report.

The urgent need for effective treatments for acute and chronic lung diseases underscores the significance of developing innovative preclinical human research tools. The 2023 ATS Workshop on Precision Cut Lung Slices (PCLS) brought together 35 experts to discuss and address the role of human tissue-derived PCLS as a unique tool for target and drug discovery and validation in pulmonary medicine. With increasing interest and usage, along with advancements in methods and technology, there is a growing need for consensus on PCLS methodology and readouts.

Lithium isotope evidence for a plumeworld ocean in the aftermath of the Marinoan snowball Earth.

The snowball Earth hypothesis predicts that continental chemical weathering diminished substantially during, but rebounded strongly after, the Marinoan ice age some 635 Mya. Defrosting the planet would result in a plume of fresh glacial meltwater with a different chemical composition from underlying hypersaline seawater, generating both vertical and lateral salinity gradients. Here, we test the plumeworld hypothesis using lithium isotope compositions in the Ediacaran Doushantuo cap dolostone that accumulated in the aftermath of the Marinoan snowball Earth along a proximal-distal (nearshore-offshore) transect in South China.

Pathogenicity of CsRV2 and CdPBV1 in Callinectes danae: An Imminent Concern for Crab Production in Brazil.

Understanding the pathogenicity of viral infections in aquatic organisms is vital due to their substantial impact on aquaculture and wild populations. This study assessed the pathogenicity of Callinectes sapidus Reovirus 2 in Callinectes danae and its effects on the metabolic, immunological and behavioural parameters. CsRV2-negative specimens were divided into CsRV2 inoculum (n = 10) and saline injection (n = 15).

Controls on spatial variation in porewater methane concentrations across United States tidal wetlands.

Tidal wetlands can be a substantial sink of greenhouse gases, which can be offset by variable methane (CH) emissions under certain environmental conditions and anthropogenic interventions. Land managers and policymakers need maps of tidal wetland CH properties to make restoration decisions and inventory greenhouse gases. However, there is a mismatch in spatial scale between point-based sampling of porewater CH concentration and its predictors, and the coarser resolution mapping products used to upscale these data.