Community Member Views on Autism Intervention: Effects of Closeness to Autistic People with Intellectual Disabilities And Nonspeaking Autistic People.

Background: Controversy regarding the neurodiversity movement (NDM), the social and medical models of disability, autism intervention goals, and causal attributions of disability contributes to divides in the autistic and autism communities. The present study investigates the views of autistic and non-autistic autistic and autism community members on these topics. We explored whether these views are shaped by having close relationships to autistic people with intellectual disabilities (ID) and nonspeaking autistic (NSA) people.

Variation in Skin Red and Yellow Undertone: Reliability of Ratings and Relevance for Perceived Social Experiences.

It is well established that skin lightness-darkness is associated with social outcomes, but little is known regarding the social salience of skin undertones (redness and yellowness). Our study addresses two related research questions on this topic: first, we ask whether red and yellow undertones are consistently perceived by observers; second, we ask whether red and yellow undertones are associated with expectations of discrimination across a range of social settings. We address these questions using novel survey data in which skin lightness-darkness and undertones are captured using CIELAB measurements and a two-dimensional categorical skin color scale.

Minimally Invasive Therapies for Knee Osteoarthritis.

Knee osteoarthritis (KOA) is a musculoskeletal disorder characterized by articular cartilage degeneration and chronic inflammation, affecting one in five people over 40 years old. The purpose of this study was to provide an overview of traditional and novel minimally invasive treatment options and role of artificial intelligence (AI) to streamline the diagnostic process of KOA. This literature review provides insights into the mechanisms of action, efficacy, complications, technical approaches, and recommendations to intra-articular injections (corticosteroids, hyaluronic acid, and plate rich plasma), genicular artery embolization (GAE), and genicular nerve ablation (GNA).

Dynamic Functional Connectivity Correlates of Trait Mindfulness in Early Adolescence.

Background: Trait mindfulness-the tendency to attend to present-moment experiences without judgment-is negatively correlated with adolescent anxiety and depression. Understanding the neural mechanisms that underlie trait mindfulness may inform the neural basis of psychiatric disorders. However, few studies have identified brain connectivity states that are correlated with trait mindfulness in adolescence, and they have not assessed the reliability of such states.

Niche partitioning and host specialisation in fish-parasitising isopods: Trait-dependent patterns from three ecosystems on the east coast of India.

Due to their large size and obligate nature, Cymothoid isopods inflict a high degree of tissue damage to fish. Still, they are understudied at an ecosystem level despite their global presence and ecological role. In this work, we collected fish host-isopod parasite data, along with their life history and ecological traits, from the northern part of the east coast of India and investigated patterns in host specialisation and preference of isopod parasites using a trait-based network perspective.

A Comprehensive Guide to Quality Assessment and Data Submission for Genomic Surveillance of Enteric Pathogens.

This document outlines the steps necessary to assemble and submit the standard data package required for contributing to the global genomic surveillance of enteric pathogens. Although targeted to GenomeTrakr laboratories and collaborators, these protocols are broadly applicable for enteric pathogens collected for different purposes. There are five protocols included in this chapter: (1) quality control (QC) assessment for the genome sequence data, (2) validation for the contextual data, (3) data submission for the standard pathogen package or Pathogen Data Object Model (DOM) to the public repository, (4) viewing and querying data at NCBI, and (5) data curation for maintaining relevance of public data.

Atomic scale insights into NaCl nucleation in nanoconfined environments.

In this work we examine the nucleation from NaCl aqueous solutions within nano-confined environments, employing enhanced sampling molecular dynamics simulations integrated with machine learning-derived reaction coordinates. Through our simulations, we successfully induce phase transitions between solid, liquid, and a hydrated phase, typically observed at lower temperatures in bulk environments. Interestingly, while generally speaking nano-confinement serves to stabilize the solid phase and elevate melting points, there are subtle variations in the thermodynamics of competing phases with the precise extent of confinement.

Speaker-independent speech inversion for recovery of velopharyngeal port constriction degreea).

For most of his illustrious career, Ken Stevens focused on examining and documenting the rich detail about vocal tract changes available to listeners underlying the acoustic signal of speech. Current approaches to speech inversion take advantage of this rich detail to recover information about articulatory movement. Our previous speech inversion work focused on movements of the tongue and lips, for which "ground truth" is readily available.

Quantification of Climate Footprints of in Coastal Human Communities of the United States Gulf Coast.

The incidence of vibriosis is rising globally with evidence of climate variability influencing environmental processes that support growth of pathogenic . The waterborne pathogen, can invade wounds and has one of the highest case fatality rates in humans. The bacterium cannot be eradicated from the aquatic environment, hence climate driven environmental conditions enhancing growth and dissemination of .

Influence of talker and accent variability on rapid adaptation and generalization to non-native accented speech in younger and older adults.

Introduction: Listeners can rapidly adapt to English speech produced by non-native speakers of English with unfamiliar accents. Prior work has shown that the type and number of talkers contained within a stimulus set may impact rate and magnitude of learning, as well as any generalization of learning. However, findings across the literature have been inconsistent, with relatively little study of these effects in populations of older listeners.

Fermenting kale ( L.) enhances its functional food properties by increasing accessibility of key phytochemicals and reducing antinutritional factors.

The properties of kale as a functional food are well established. We sought to determine how fermentation further enhances these properties. We tested different fermentation conditions: (i) spontaneous fermentation with naturally occurring bacteria, (ii) spontaneous fermentation with 2% salt, (iii) , (iv) , (v) mixture of and , (vi) mixture of , , and We quantified selected bioactive components using high-performance liquid chromatography (HPLC) and antinutritional factors using a gravimetric method and spectrophotometry.

An Online Nanoinformatics Platform Empowering Computational Modeling of Nanomaterials by Nanostructure Annotations and Machine Learning Toolkits.

Modern nanotechnology has generated numerous datasets from and studies on nanomaterials, with some available on nanoinformatics portals. However, these existing databases lack the digital data and tools suitable for machine learning studies. Here, we report a nanoinformatics platform that accurately annotates nanostructures into machine-readable data files and provides modeling toolkits.

Profiles of Risk, Allostatic Load, and Mental Health in Low-Income Children.

Most health disparities originate in childhood and extend across the lifespan. However, studies on health disparities have been predominately focused on adults. This study evaluated the biological and psychosocial consequences of exposure to chronic adversity among 491 low-income children 8 to 12 years old (52.

Plant resistance and predators influence the density dependence of herbivore survival and distribution of herbivory.

Plant resistance and predators can influence density-dependent survivorship and growth of herbivores, and their damage to plants. Although the independent effects of plant resistance and predators on herbivores and herbivory are well known, little is known about their interactive and density-dependent effects on herbivores and the amount and distribution of damage on plants. These relationships are important for understanding how herbivore and plant populations influence each other.

Building Digital Twins for Cardiovascular Health: From Principles to Clinical Impact.

The past several decades have seen rapid advances in diagnosis and treatment of cardiovascular diseases and stroke, enabled by technological breakthroughs in imaging, genomics, and physiological monitoring, coupled with therapeutic interventions. We now face the challenge of how to (1) rapidly process large, complex multimodal and multiscale medical measurements; (2) map all available data streams to the trajectories of disease states over the patient's lifetime; and (3) apply this information for optimal clinical interventions and outcomes. Here we review new advances that may address these challenges using digital twin technology to fulfill the promise of personalized cardiovascular medical practice.

Sexual Identity Continuity and Change in a U.S. National Probability Sample of Sexual Minority Adults: Associations With Mental Health and Problematic Substance Use.

Objective: Sexual minority disparities in behavioral health (e.g., mental health and substance use) are well-established.

Child-directed speech in a large sample of U.S. mothers with low income.

Research on early language input and socioeconomic status typically relies on correlations in small convenience samples. Using data from Baby's First Years, this paper assesses the causal impact of monthly, unconditional cash transfers on child-directed speech and child vocalizations among a large, racially diverse sample of low-income U.S.

Subjective Successful Aging in the Presence of Mobility Disability.

Background And Objectives: Researchers often define successful aging as freedom from disability and disease, yet the perceptions of older adults living with disability challenge this conception, demonstrating that they can indeed age successfully. This paper adapts a framework of successful aging with disability, basing it on the subjective assessment of key components contributing to success among older adults living with mobility disability due to multiple sclerosis.

Research Design And Methods: Employing a qualitative, theory-grounded methodology, we conducted semi-structured interviews with 20 individuals aged 60-75 who live with mobility disability attributed to multiple sclerosis.

Preliminary Validation of the Children's Auditory Performance Scale (CHAPS) and the Auditory Processing Domain Questionnaire (APDQ) in Greek Cypriot Children.

Background: Identification of auditory processing disorders is achieved using questionnaires along with linguistic, non-linguistic, and auditory processing tests. Notably, the questionnaires "Children's Auditory Performance Scale" (CHAPS) and "Auditory Processing Domain Questionnaire" (APDQ) are widely recognized and used. The current study investigated the psychometric properties of the CHAPS and APDQ in Greek Cypriot children.

Institutional Management Competence for Addressing Illegal Wildlife Trade: Insights from Uruguay.

The illegal wildlife trade (IWT) is a global phenomenon that adversely affects biodiversity and human well-being. Understanding how institutions manage this trade is crucial for reducing its negative impacts. Latin America has the fewest IWT studies globally; thus, science in support of more effective institutional management of IWT is limited.

Dynamic functional connectivity correlates of trait mindfulness in early adolescence.

Background: Trait mindfulness, the tendency to attend to present-moment experiences without judgement, is negatively correlated with adolescent anxiety and depression. Understanding the neural mechanisms underlying trait mindfulness may inform the neural basis of psychiatric disorders. However, few studies have identified brain connectivity states that correlate with trait mindfulness in adolescence, nor have they assessed the reliability of such states.