131 results match your criteria: "University of Manchester Oxford Road[Affiliation]"
Angew Chem Int Ed Engl
April 2001
Department of Chemistry University of Manchester Oxford Road, Manchester, M13 9PL (UK).
Angew Chem Int Ed Engl
January 2001
Department of Chemistry The University of Manchester Oxford Road, Manchester, M13 9PL (UK).
Angew Chem Int Ed Engl
January 2001
Department of Chemistry The University of Manchester Oxford Road, Manchester, M13 9PL, UK, Fax: (+44) 161-275-4616.
Angew Chem Int Ed Engl
December 2000
Department of Chemistry The University of Manchester Oxford Road, Manchester M13 9PL, UK, Fax: (+44) 161-275-4939.
Curr Biol
October 1999
School of Biological Sciences 2.205 Stopford Building University of Manchester Oxford Road, Manchester, M13 9PT, UK.
Background: The yeast CDC9 gene encodes a DNA ligase I activity required during nuclear DNA replication to ligate the Okazaki fragments formed when the lagging DNA strand is synthesised. The only other DNA ligase predicted from the yeast genome sequence, DNL4/LIG4, is specifically involved in a non-homologous DNA end-joining reaction. What then is the source of the DNA ligase activity required for replication of the yeast mitochondrial genome?
Results: We report that CDC9 encodes two distinct polypeptides expressed from consecutive in-frame AUG codons.
Modification of endogenous eicosanoid synthesis by dietary n-3 fatty acid supplementation reduces febrile responses, but the mechanisms underlying these effects in vivo have not been determined. In the present study, local inflammation was induced by intramuscular injection ofturpentine in rats fed control or n-3 supplemented diets for 8-9 weeks. In animals fed the control diet, turpentine induced fever, hypermetabolism, marked local inflammation (oedema), increased plasma IL-6 concentrations and raised cerebrospinal fluid (CSF) concentrations of PGE2.
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