alkaloids - acid, anion-driven fluorescent INHIBIT logic gates with a receptor-fluorophore-spacer-receptor format and PET and ICT mechanisms.

The fluorescent natural products, quinine, quinidine, cinchonine and cinchonidine are demonstrated as H-enabled, halide-disabled (Cl, Br or I) INHIBIT and INHIBIT-OR combinatorial logic gates in water. More fluorescent natural products with intrinsic logic properties await to be discovered.

Solvent-polarity reconfigurable fluorescent 4-piperazino--aryl-1,8-naphthalimide crown ether logic gates.

Four compounds 1-4 were designed and synthesised, comprising a 4-amino--aryl-1,8-naphthalimide fluorophore, a piperazine receptor, and an aryl group, as fluorescent logic gates. At the imide position, the substituent is phenyl (1), 1,2-dimethoxyphenyl (2), benzo-15-crown-5 (3), or benzo-18-crown-6 (4). Molecules 1 and 2 are constructed according to a fluorophore-spacer-receptor format, while 3 and 4 are engineered according to a receptor-spacer-fluorophore-spacer-receptor format based on photoinduced electron transfer and internal charge transfer mechanisms.

4-Amino-1,8-naphthalimide-ferrocene conjugates as potential multi-targeted anticancer and fluorescent cellular imaging agents.

Herein we present eight ferrocenyl 4-amino-1,8-naphthalimides. Designed as fluorescent logic gates for acidity and oxidisability, the molecules have been repurposed as anti-proliferation and cellular imaging agents. The compounds were studied against MCF-7 and K562 cancer cell lines by the MTT method.