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The Potential of Naturally Derived Compounds for Treating Chronic Kidney Disease: A Review of Autophagy and Cellular Senescence.
Int J Mol Sci
December 2024
Department of Medicine, Faculty of Medicine, University of Malaysia (UM), Kuala Lumpur 59100, Malaysia.
Article Synopsis
- Chronic kidney disease (CKD) is a progressive condition leading to kidney failure, and while there are treatments to manage it, none can reverse the damage.
- Traditional Chinese Medicine (TCM) offers an alternative with potentially fewer side effects, but more research is needed to understand how its natural products can help improve CKD, particularly in relation to mechanisms like autophagy and cellular aging.
- This review looks into TCM's natural products, their active components, and their possible roles in protecting kidney function and aiding in the management of CKD alongside conventional therapies.