Therapeutic potential of dopamine and serotonin in inflammation and cancer: Insights into immune regulation.

Introduction: This review explores the significant roles of neurotransmitters, focusing on dopamine and serotonin, in inflammation and cancer. These neurotransmitters are vital for neural signaling and play crucial roles in various physiological and pathological processes.

Materials And Methods: We conducted an extensive literature review, focusing on studies published between 2013 and 2024, using databases such as PubMed, Google Scholar, and Scopus.

Impact of chronic opioid on cognitive function and spermatogenesis in rat: An experimental study.

Background: Opioid analgesics like morphine and methadone are widely used for managing severe pain; however, concerns over their potential misuse and adverse effects on the brain and reproductive system are significant.

Objective: We aimed to investigate their impacts on spermatogenesis and cognitive function in male Norway rats.

Materials And Methods: In this experimental study, 36 male Norway rats (250-300 gr, 6 months old) were divided into 6 groups: low-dose morphine, high-dose morphine, low-dose methadone, high-dose methadone, positive control (received normal saline at 5 mg/kg), and negative control (received no treatment).

The use of herbs in the treatment of COVID-19.

Objective: herbs are the only extant genus in its family, Ephedraceae, and order, Ephedrales. It has been prescribed in traditional medicine for improving headaches and respiratory infections. On the other hand, because the coronavirus disease 2019 (COVID-19) causes respiratory problems and COVID-19 pandemic is the most widespread outbreak that has affected humanity in the last century, the current review aims using literature search to investigate the effects of the herbs compounds on COVID-19 to supply a reference for its clinical application in the inhibition and remedy of COVID-19.

Urban morphology detection and it's linking with land surface temperature: A case study for Tehran Metropolis, Iran.

Expansion of urban areas and alteration of natural land cover exacerbate the local climate change. To find out the effect of land cover changes on the local climate, in this study, the Local Climate Zone (LCZ) concept was utilized to detect urban morphology in Tehran Metropolis. LCZ and Land Surface Temperature (LST) can be identified and classified based on available remote sensing products.

Relationship between dietary diversity score and general health in female students.

Background: Adolescence is a critical period with respect to mental and psychological issues. The role of nutrients is well known in health condition in adolescents, but little emphasis is placed on total diet quality. Dietary diversity score (DDS) is often used to assess diet quality.

Changes in Essential Oil Profile of Thymus daenensis Celak., Thymus fedtschenkoi Ronniger., and Thymus vulgaris L. Under Methyl Jasmonate Treatment.

Background: TThymus plants are well-known medicinal plants and it is believed that the pharmaceutical and therapeutical properties of these plants are related to their essential oils. The quality and quantity of the essential oils, as a secondary metabolite of an aromatic plant, are directly related to the physiological state of the plant. The role of jasmonates in the plant as signal molecules in mediation and up-regulation of plant defense and secondary metabolism processes is well recognized.

Mercury concentration in the feathers of birds from various trophic levels in Fereydunkenar International wetland (Iran).

Mercury (Hg) is one of the main global pollutants that may biomagnify in food nets, especially in wetlands. Birds may be useful in the biomonitoring of Hg in such habitats and may even serve in vivo samples. This paper examined Hg concentration in the feathers of seven bird species foraging on Fereydunkenar International wetland (in 2013).

Methods for artifact detection and removal from scalp EEG: A review.

Electroencephalography (EEG) is the most popular brain activity recording technique used in wide range of applications. One of the commonly faced problems in EEG recordings is the presence of artifacts that come from sources other than brain and contaminate the acquired signals significantly. Therefore, much research over the past 15 years has focused on identifying ways for handling such artifacts in the preprocessing stage.

In vitro enhancement of psoralen as an important anticancer compound in Psoralea corylifolia through precursor feeding.

Context: Psoralea corylifolia L. (Fabacese) is rich source of bioactive compounds, which endows the plant with immense value for its use in pharmaceuticals, health, and body-care products.

Objective: The current study was designed (i) for the determination of psoralen from callus derived from different plant parts, and (ii) for the enhancement of psoralen in in vitro condition with the treatment of various psoralen pathway precursors.

Large pore volume mesoporous copper particles and scaffold microporous carbon material obtained from an inorganic-organic nanohybrid material, copper-succinate-layered hydroxide.

Copper-succinate-layered hydroxide (CSLH), a new nanohybrid material, was synthesized as an inorganic-organic nanohybrid, in which organic moiety was intercalated between the layers of a single cation layered material, copper hydroxide nitrate. Microporous scaffold carbon material was obtained by thermal decomposition of the nanohybrid at 500 °C under argon atmosphere followed by acid washing process. Furthermore, the heat-treated product of the nanohybrid at 600 °C was ultrafine mesoporous metallic copper particles.

Production of a recombinant anti-human CD4 single-chain variable-fragment antibody using phage display technology and its expression in Escherichia coli.

Single-chain variable fragment (scFv) is a fusion protein of the variable regions of the heavy (VH) and light (VL) chains of immunoglobulin, connected with a short linker peptide of 10 to about 20 amino acids. In this study, the scFv of a monoclonal antibody against the third domain of human CD4 was cloned from OKT4 hybridoma cells using the phage display technique and produced in E. coli.

In vitro isolation, elicitation of psoralen in callus cultures of Psoralea corylifolia and cloning of psoralen synthase gene.

Psoralen, an important furanocoumarin occurring abundantly in seeds of Psoralea corylifolia is used as an anticancerous compound against leukemia and other cancer cell lines. Evaluation and isolation of psoralen from the calluses derived from different plant parts, viz. cotyledons, nodes, leaves and roots have been done in the present case for the first time.