AAPM MPLA case: Betrayal versus disillusionment.

This work of fiction depicts a scenario in which a faculty member felt they were criticized unfairly and inappropriately for honesty on a faculty survey, which reflected poorly on administration. The faculty member was left struggling with how to respond to conflicting feelings and perception of misaligned goals and mission. Simultaneously, the department chair felt they were blindsided by issues that could have been addressed without the embarrassment of a poor survey.

Exploring the role of motherhood in healthcare engagement for women living with HIV in the USA.

Mothers living with HIV are faced with managing their own complex healthcare and wellness needs while caring for their children. Understanding the lived experiences of mothers living with HIV, including grandmothers and mothers with older children - who are less explicitly represented in existing literature, may guide the development of interventions that best support them and their families. This study sought to explore the role of motherhood and related social/structural factors on engagement with HIV care, treatment-seeking behaviour, and overall HIV management among mothers living with HIV in the USA to inform such efforts.

Improving care practices of the patient with type 2 diabetes in community health centers.

Background: Diabetes ranks seventh in morbidity and mortality in the United States. In addition, more than 25 million Americans living with diabetes depend on community health centers (CHCs) for primary care.

Local Problem: Preimplementation data in a group of CHCs indicated poor adherence to standards of care practices as recommended by the American Diabetes Association (ADA) with quarterly A1c (33.

Total workflow uncertainty of frameless radiosurgery with the Gamma Knife Icon cone-beam computed tomography.

Objective: Frameless treatment with the Gamma Knife Icon is still relatively new as a treatment option. As a result, additional confidence/knowledge about the uncertainty that exists within each portion of the treatment workflow could be gained especially regarding steps that have not been previously studied in the literature.

Methods: The Icon base delivery device (Perfexion) uncertainty is quantified and validated.

Analysis of nonideality: insights from high concentration simulations of sedimentation velocity data.

The Aviv fluorescence detection system (Aviv-FDS) has allowed the performance of sedimentation velocity experiments on therapeutic antibodies in highly concentrated environments like formulation buffers and serum. Methods were implemented in the software package SEDANAL for the analysis of nonideal, weakly associating AUC data acquired on therapeutic antibodies and proteins (Wright et al. Eur Biophys J 47:709-722, 2018, Anal Biochem 550:72-83, 2018).

Acute damage to the blood–brain barrier and perineuronal net integrity in a clinically-relevant rat model of traumatic brain injury.

Closed-head, frontal impacts in which the brain undergoes both lateral and rotational acceleration comprise the majority of human traumatic brain injury (TBI). Here, we utilize a clinically relevant model to examine the effects of a single concussion on aspects of brain integrity: the blood-brain barrier, the perineuronal nets (PNNs), and diffuse axonal injury. Adult, male Sprague-Dawley rats received either a frontal, closed-head concussive TBI, or no injury and were evaluated at 1- or 7-day post-injury.

Risk-Reducing Salpingo-Oophorectomy and Breast Cancer Risk Reduction in the Gynecologic Oncology Group Protocol-0199 (GOG-0199).

Background: Risk-reducing salpingo-oophorectomy (RRSO) has been associated with approximately 50% breast cancer risk reduction among women with a pathogenic variant in or (), a finding that has recently been questioned.

Methods: We estimated incidence rates of breast cancer and all cancers combined during 5 years of follow-up among participants selecting RRSO or ovarian cancer screening (OCS) among women with a pathogenic variant or strong breast and/or ovarian cancer family history. Ovarian or fallopian tube or peritoneal cancer incidence rates were estimated for the OCS group.

Chasing Zero Harm in Radiation Oncology: Using Pre-treatment Peer Review.

The Joint Commission has encouraged the healthcare industry to become "High Reliability Organizations" by "Chasing Zero Harm" in patient care. In radiation oncology, the time point of quality checks determines whether errors are prevented or only mitigated. Thus, to "chase zero" in radiation oncology, peer review has to be implemented prior to treatment initiation.

Women's decision-making about self-protection during sexual activity in the deep south of the USA: a grounded theory study.

Many women continue to become infected with HIV, particularly in the Southeastern USA, despite widespread knowledge about methods to prevent its sexual transmission. This grounded theory investigation examined the decision-making process women use to guide their use or non-use of self-protective measures when engaging in sexual activity. Participants included women in the Mississippi cohort of the Women's Interagency HIV Study who were infected with or at high risk for HIV.

The Evolution of the Society of Trauma Nurses' Leadership Institute.

The Society of Trauma Nurses (STN) understands the increasing complexity of trauma care and the vital leadership role nurses play. In 2009, the STN took the initiative to form a Leadership Committee tasked with researching the possibility of developing a mechanism to offer trauma leaders opportunities in leadership development. Investigation and collaboration among the committee members, with input from the Board of Directors and the organization's executive director, resulted in the STN Leadership Institute.

Interleukin-10/Ceftriaxone prevents E. coli-induced delays in sensorimotor task learning and spatial memory in neonatal and adult Sprague-Dawley rats.

Intrauterine infection during pregnancy is associated with early activation of the fetal immune system and poor neurodevelopmental outcomes. Immune activation can lead to alterations in sensorimotor skills, changes in learning and memory and neural plasticity. Both interleukin-10 (IL-10) and Ceftriaxone have been shown to decrease immune system activation and increase memory capacity, respectively.

The impact of problem-based learning on students' perceptions of preparedness for advanced pharmacy practice experiences.

Objectives: To evaluate graduating pharmacy students' perceptions of their preparedness for advanced pharmacy practice experiences and the effectiveness of problem-based learning in their preparation.

Methods: A survey instrument was administered anonymously in May 2004 and May 2005 to graduating pharmacy students of the University of Mississippi School of Pharmacy.

Results: Students reported that the areas in which problem-based learning prepared them most effectively for advanced pharmacy practice experiences were retrieval of medical information (80%), discussion of disease states and drug therapies at the basic science level (56%), and evaluation of the appropriateness of a medication regimen based on patient specific information (50%).

Sexual assault: the physician's role in prevention and treatment.

Rape is a crime which occurs to over 12 million women. It has a substantial impact on the physical, psychological and social health of the victim. It is defined as the carnal knowledge of a person forcibly and against their will and includes successful and unsuccessful assaults.

Role of technetium-99m sestamibi myocardial imaging in the emergency department evaluation of chest pain.

The use of technetium-99m sestamibi myocardial imaging is rapidly becoming a state of the art methodology for the emergency department evaluation of patients with chest pain. The following case report represents the first emergency department sestamibi scan ordered at the University of Mississippi Medical Center and is used to discuss the logistics and indications for such tests. A general guideline for ordering sestamibi scans has been developed for use in the emergency department.

Drownings in Mississippi 1992-1994: frequencies and distribution.

This investigation was conducted to determine the mortality rate due to drownings in Mississippi from 1992-1994. Drownings were defined as unintentional deaths from asphyxia while submerged or within 24 hours of submersion. Death certificate data including ICD-9 codes related to drownings, were received from the Mississippi State Department of Health.