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Stratified Simple Random Sampling Versus Volunteer Community-Wide Sampling for Estimates of COVID-19 Prevalence.

Am J Public Health

July 2023

Rachel J. Keith, Rochelle H. Holm, Alok R. Amraotkar, Ted Smith, Ray Yeager, and Aruni Bhatnagar are with the Christina Lee Brown Envirome Institute, School of Medicine, University of Louisville, Louisville, KY. Megan M. Bezold, Adrienne M. Bushau-Sprinkle, Krystal T. Hamorsky, Kathleen T. Kitterman, and Kenneth E. Palmer are with the Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases, University of Louisville. J. Michael Brick is with Westat Inc, Rockville, MD.

To evaluate community-wide prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using stratified simple random sampling. We obtained data for the prevalence of SARS-CoV-2 in Jefferson County, Kentucky, from adult random (n = 7296) and volunteer (n = 7919) sampling over 8 waves from June 2020 through August 2021. We compared results with administratively reported rates of COVID-19.

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