114 results match your criteria: "University of Lisbon Lisbon[Affiliation]"

Article Synopsis
  • S-adenosylhomocysteine hydrolase deficiency is an autosomal recessive metabolic disorder disrupting the methionine cycle, which can range from severe symptoms to asymptomatic cases.
  • Two clinically asymptomatic siblings from Pakistan were diagnosed with mild chronic liver failure and other mild symptoms, with one sibling showing improvements after dietary changes.
  • The research highlights a specific genetic variant common in South Asia and suggests this milder form of the disease may be underdiagnosed, emphasizing the need for better therapeutic management to prevent future health complications.
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Fermented milk products play a vital role in the diets of Ethiopians. They are produced from either spontaneous fermentation or back-slopping methods at the household level, in which lactic acid bacteria (LAB) and yeasts predominate. As a result, the processing steps are not standardized and overall safety is still of public health relevance.

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Article Synopsis
  • - Cylindromas are uncommon, non-cancerous tumors mostly found on the scalp and face, and they are more common in women, appearing usually in people in their 20s or 30s.
  • - These tumors can appear as either single or multiple nodules; multiple ones are often associated with mutations in the CYLD gene, especially in a condition called CYLD cutaneous syndrome.
  • - A case study is presented involving a 61-year-old man with multiple cylindromas on his scalp, which led to genetic testing and the discovery of a new harmful variant in the CYLD gene.
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Current pest management relies extensively on pesticide application worldwide, despite the frequent rise of pesticide resistance in crop pests. This is particularly worrisome because resistance is often not costly enough to be lost in populations after pesticide application, resulting in increased dependency on pesticide application. As climate warming increases, effort should be put into understanding how heat tolerance will affect the persistence of pesticide resistance in populations.

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The Afrotropics are experiencing some of the fastest urbanisation rates on the planet but the impact of city growth on their rich and unique biodiversity remains understudied, especially compared to natural baselines. Little is also known about how introduced species influence β-diversity in these contexts, and how patterns coincide with native ranges of species. Here we investigated how tree assemblages of the endemic-rich Afrotropical island of São Tomé differed between urban, rural and natural zones.

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Multiple cues are often used for mate choice in complex environments, potentially entailing mismatches in the information conveyed by different sources. We address the consequences of this information mismatch for receivers using the spider mite , in which virgin females are highly valuable mates compared to mated females, given first male sperm precedence. Accordingly, males are known to prefer virgins and distinguish them using cues from the females themselves and that they leave on the substrate.

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Objectives: to analyze clinical outcomes in newborns of pregnant women with COVID-19.

Methods: integrative review conducted in PubMed, Web of Knowledge, SCOPUS, CINHAL; 2,111 studies were obtained, and 8 articles comprised the final sample.

Results: clinical outcomes in neonates of pregnant women positive for COVID-19 were classified according to the following categories: a) contamination by COVID-19, reported in 62.

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Temperature, humidity, and ionisation effect of iodine oxoacid nucleation.

Environ Sci Atmos

May 2024

Institute for Atmospheric and Earth System Research/Physics, Faculty of Science, University of Helsinki Helsinki Finland

Article Synopsis
  • * The study found that particle formation rates due to ion-induced processes are stable across temperature changes, while neutral particle formation rates increase significantly when temperatures drop from +10 °C to -10 °C.
  • * Despite higher ionization rates, the formation of charged clusters is unlikely to be enhanced in upper tropospheric conditions; instead, neutral nucleation is expected to dominate, with humidity having little effect unless extremely low.
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Introduction: We aimed to expand the range of the frontotemporal dementia (FTD) phenotypes assessed by the Clinical Dementia Rating Dementia Staging Instrument plus National Alzheimer's Coordinating Center Behavior and Language Domains (CDR plus NACC FTLD).

Methods: Neuropsychiatric and motor domains were added to the standard CDR plus NACC FTLD generating a new CDR plus NACC FTLD-NM scale. This was assessed in 522 mutation carriers and 310 mutation-negative controls from the Genetic Frontotemporal dementia Initiative (GENFI).

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Article Synopsis
  • Pathogen genomic epidemiology can enhance our understanding of tropical diseases, like malaria, aiding in intervention planning and monitoring efforts for better control and elimination.
  • The study analyzed 1,474 high-quality parasite genomes from 31 countries, revealing significant genetic diversity, especially in Latin America, where distinct populations and sub-populations exist tied to transmission intensity.
  • Findings show adaptive evolution in key genes related to parasite survival, providing insights into drug resistance, immune evasion, and transmission dynamics essential for effective control strategies.
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Background: In September 2012, a comprehensive survey of Pico Island was conducted along an elevational transect, starting at Manhenha (10 m a.s.l.

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Psychodermatology is a subdiscipline of dermatology at the intersection of dermatology, psychiatry, and psychology. In dermatology clinical practice, patients may present with skin disease that affects their mental health, or skin disorders induced or worsened by psychological/psychiatric problems so there is a need for specialised education of dermatologists, as well as multidisciplinary teams, to achieve better management of these patients. Understanding the interaction between the central nervous system and the skin underlying psychocutaneous disorders could help identify alternative therapies that may improve patient well-being.

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Healthy Social Network Use and Well-Being during Adolescence: A Biopsychosocial Approach.

Children (Basel)

October 2023

Institute of Environmental Health (ISAMB), Faculty of Medicine, University of Lisbon, Av. Professor Egas Moniz, 1649-028 Lisbon, Portugal.

Screen time and the use of social networks is the most frequent form of leisure time occupation and socializing for adolescents. The present study is aimed at understanding and characterizing, from an ecological perspective, what distinguishes healthy and less healthy or even dependent use of social media in young people and the influence on adolescents' well-being. This paper is based on the Health Behaviour in School-aged Children (HBSC) from 2022, a survey carried out every 4 years, in collaboration with the World Health Organisation (WHO), following an international protocol.

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Background: Handicap is a patient-centered measure of health status that encompasses the impact of social and physical environment on daily living, having been assessed in advanced and late-stage Parkinson's Disease (PD).

Objective: To characterize the handicap of a broader sample of patients.

Methods: A cross-sectional study of 405 PD patients during the MDS-UPDRS Portuguese validation study, using the MDS-UPDRS, Unified Dyskinesias Rating Scale, Nonmotor symptoms questionnaire, PDQ-8 and EQ-5D-3L.

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Introduction: Parental perceptions of a child's weight status may influence family readiness to foster healthy behaviors. Our aim was to observe parental perceptions of their child's weight status in two time periods and in multiple population subgroups.

Methods: Data were collected in two national projects, 2009 - 2010 (n = 6577) and 2016 - 2017 (n = 7594), in public and private kindergartens and primary schools in Portugal (children aged three to 10 years old).

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Sea lamprey is an anadromous and semelparous fish without homing behaviors. Despite being a freshwater, free-living organism for a large part of their life cycle, its adulthood is spent as a parasite of marine vertebrates. In their native European range, while it is well-established that sea lampreys comprise a single nearly-panmictic population, few studies have further explored the evolutionary history of natural populations.

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The approach of surgical techniques has evolved significantly over the last decade, with natural orifice surgeries replacing traditional open approaches. In 2016, Angkoon Anuwong, in Thailand, demonstrated it was possible to perform thyroidectomies in a series of patients by a transoral endoscopic ap-proach - transoral endoscopy thyroidectomy vestibular approach (TOETVA) - with similar complication rates when compared to conventional surgeries. This transoral surgery has become a safe alternative with better cosmetic results, compared to conventional open-route procedures, like Kocher cervi-cotomy.

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Article Synopsis
  • Psoriasis is a prevalent and long-term inflammatory skin condition in Portugal, affecting about 4.4% of the population, highlighting a significant personal, social, and economic burden.
  • The study involved a comprehensive survey with 6,381 individuals, revealing that over 70% had active symptoms, yet only 12% were receiving systemic treatment for the disease.
  • Many individuals reported comorbidities and a considerable impact on daily life and sexual well-being, emphasizing the necessity for better management and awareness of psoriasis and its repercussions.
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Epidemics in general and dengue in particular surcharge the health services and the economy. However, the fighting actions are circumscribed to the health sector despite the known positive economic impacts that the investments in water supply and sanitation services (WSS) may cause on society and public health. Besides the fact that urban WSS infrastructure is closely linked to disease prevention, in Brazil, the user's perception and demand are very few and many institutional aspects, like the integration between local WSS, health, environment, and development of city councils, need to be improved and better aligned.

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In this study, we show that limitations in the representation of land cover and vegetation seasonality in the European Centre for Medium-Range Weather Forecasting (ECMWF) model are partially responsible for large biases (up to ∼10°C, either positive or negative depending on the region) on the simulated daily maximum land surface temperature (LST) with respect to satellite Earth Observations (EOs) products from the Land Surface Analysis Satellite Application Facility. The error patterns were coherent in offline land-surface and coupled land-atmosphere simulations, and in ECMWF's latest generation reanalysis (ERA5). Subsequently, we updated the ECMWF model's land cover characterization leveraging on state-of-the-art EOs-the European Space Agency Climate Change Initiative land cover data set and the Copernicus Global Land Services leaf area index.

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Serious Game-based Psychosocial Intervention to Foster Prosociality in Cyberbullying Bystanders.

Psychosoc Interv

May 2022

Instituto Superior Técnico GAIPS Porto Salvo Portugal Instituto Superior Técnico, INESC-ID, GAIPS, Porto Salvo, Portugal.

Bystanders of cyberbullying play an important role in the resolution of such situations and therefore, it is beneficial to promote self-regulation strategies that enable them to engage in prosocial behavior in these contexts. We propose that serious game-based psychosocial interventions with profile-based social agents can encourage prosocial bystander behavior in cyberbullying. A pilot quasi-experimental study with repeated and pre/post measurements was performed.

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