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knock-down decreases tumoral character of colorectal cancer cells and .
Am J Cancer Res
January 2022
PEIRENE Laboratory, EA 7500, Glycosylation and Cell Differentiation, Faculty of Sciences and Technology, University of Limoges Limoges F-87060, France.
Tumor cells have a modified glycosylation profile that promotes their evolution and/or their maintenance in the tumor. Sialylation is a type of glycosylation that is often altered in cancers. RNA-Seq database analysis revealed that the sialyltransferase gene is significantly overexpressed at all stages of colorectal cancer (CRC).
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