2 results match your criteria: "University of Lille Nord de France and Institut Pasteur de Lille[Affiliation]"

TRα protects against atherosclerosis in male mice: identification of a novel anti-inflammatory property for TRα in mice.

Endocrinology

July 2014

Institut de Génomique Fonctionnelle de Lyon (C.B., L.C., A.D., J.S., K.G.), Université de Lyon, Université Lyon 1, Centre National de la Recherche Scientifique. Institut National de la Recherche Agronomique, Ecole Normale Supérieure de Lyon, 69364 Lyon, France; Inserm Unité 1011 (S.F., D.D.), University of Lille Nord de France and Institut Pasteur de Lille, 59000 Lille, France; and Inserm Equipe Région-Inserm 22/Equipe Associée 4173 (M.B.) and Anira-ANIPHY (P.d.C.), Faculté Rockefeller, Université Lyon 1, 69008 Lyon, France.

Hypothyroidism is associated with an increased occurrence of atherosclerosis, suggesting some protective role for thyroid hormones (THs). Hypercholesterolemia is one of the major risk factor to develop this disease. Here, we show that the well-known TH cholesterol lowering effect was dependent on TH nuclear receptor (TR)β liver activity.

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Recent findings have identified roles for the immune system in what were previously considered to be prototypic metabolic diseases, and metabolic control has emerged as an important determinant of immune function. Giovanna Chimini, Lee Leserman, Diane Mathis and Philippe Naquet organized the EMBO Workshop on Immunology & Metabolism, which took place in January 2011 at the Centre d'Immunologie de Marseille-Luminy (CIML) in Marseille, France. The meeting brought together approximately 100 scientists to discuss interactions between metabolism and inflammation.

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