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Recent advances in antiplatelet agents.
Curr Med Chem
March 2002
Department of Medicinal Chemistry, University of Li ge, 1, av. de l H pital, B36 Sart-Tilman, Liege, 4000 Liege, Belgium.
Article Synopsis
- Platelet aggregation is crucial in diseases like heart attacks and strokes, highlighting the need for effective antiplatelet therapies.
- Historically, aspirin has been the primary antiplatelet drug, but newer options including ADP receptor antagonists, phosphodiesterase inhibitors, and GP IIb/IIIa receptor antagonists have emerged.
- This review focuses on the recent developments in these antiplatelet agents, particularly their chemical properties and potential clinical applications.