4 results match your criteria: "University of Leiden School of Medicine[Affiliation]"
Brain plasticity in neonatal brachial plexus palsies: quantification and comparison with adults' brachial plexus injuries.
Childs Nerv Syst
February 2024
Department of Neurosurgery, University of Leiden School of Medicine, Leiden, Holland.
Article Synopsis
- - The study aimed to compare brain plasticity between two groups with brachial plexus palsies: newborns (NBPP) and adults (NNBPP) who underwent nerve transfers, using the plasticity grading scale (PGS).
- - A total of 153 NNBPP patients and 35 NBPP babies were included, revealing that babies scored higher on the PGS after surgery compared to adults, indicating better brain rewiring in infants.
- - The results showed that while both groups had similar rehabilitation compliance, newborns displayed significantly greater potential for brain plasticity than adults, making them more capable of recovering function after nerve transfers.
Brain plasticity and age after restoring elbow flexion with distal nerve transfers in neonatal brachial plexus palsy and nonneonatal traumatic brachial plexus injury using the plasticity grading scale.
J Neurosurg
December 2023
2Department of Neurosurgery, University of Leiden School of Medicine, Leiden, Holland.
Article Synopsis
- Ulnar and median nerve transfers to the musculocutaneous nerve (MCN) are performed to help restore elbow flexion in patients with severe brachial plexus injuries, but the impact of patient age on brain plasticity during recovery is unclear.
- In a study with 66 patients divided into neonatal (NBPP) and nonneonatal (NNBPI) groups, the results showed that all NBPP patients achieved a high level of control (PGS grade of 4), while only 47.7% of NNBPI patients reached the same level.
- Age was found to be a significant predictor of plasticity, indicating that younger patients (like those with NBPP)
Phrenic to musculocutaneous nerve transfer for traumatic brachial plexus injuries: analyzing respiratory effects on elbow flexion control.
J Neurosurg
July 2019
1Peripheral Nerve and Brachial Plexus Surgery Program, Department of Neurosurgery, and.
Objective: In this study, the authors sought to identify the relationship between breathing and elbow flexion in patients with a traumatic brachial plexus injury (TBPI) who undergo a phrenic nerve (PN) transfer to restore biceps flexion. More specifically, the authors studied whether biceps strength and the maximal range of active elbow flexion differ between full inspiration and expiration, and whether electromyography (EMG) activity in the biceps differs between forced maximum breathing during muscular rest, normal breathing during rest, and at maximal biceps contraction. All these variables were studied in a cohort with different intervals of follow-up, as the authors sought to determine if the relationship between breathing movements and elbow flexion changes over time.
View Article and Find Full Text PDFFirst-trimester ultrasonography findings in women with a history of recurrent pregnancy loss.
Am J Obstet Gynecol
January 1993
University of Leiden School of Medicine, The Netherlands.
Objective: We tabulated first-trimester ultrasonography findings in women with recurrent pregnancy loss and determined the rate of subsequent pregnancy loss and live births after demonstration of a live embryo.
Study Design: Sixty-seven women with three or more recurrent miscarriages underwent first-trimester ultrasonography and were prospectively followed through 101 pregnancies.
Results: First-trimester ultrasonography showed a dead embryo in seven pregnancies.