436 results match your criteria: "University of Leeds. Leeds[Affiliation]"

Development of sustainable synthesis methods of organic electrode materials (OEMs) for sodium (Na)-ion batteries must take hold rapidly in large scale-synthesis if subsequent commercialisation is to occur. We report a facile and rapid gram-scale synthesis method based on microwave irradiation for disodium naphthalene-2,6-dicarboxylate (Na-NDC) and mono/disodium benzene-1,4-dicarboxylate (Na-BDC) as model compounds. Phase purity and formation of materials was confirmed by various characterisation techniques.

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Background: Identification of rheumatoid arthritis (RA) in primary care is challenging and often delayed. Anti-cyclic citrullinated peptide (anti-CCP) antibody testing of people presenting to primary care with new-onset musculoskeletal symptoms without synovitis could help address this; those testing positive are at increased risk of developing RA.

Aim: To explore how primary care clinicians currently identify and refer patients with suspected RA, and the behaviours required to implement a prediction model for guiding targeted anti-CCP testing for non-specific musculoskeletal symptoms in primary care.

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The aim of this investigation was to comparatively assess the antioxidant and polyphenol compounds in fresh moringa pods sourced from two different regions in Australia, namely Queensland (QLD) and Western Australia (WAU). Total polyphenol content varied between 1.64 and 5.

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Deep learning models are used to minimize the number of polyps that goes unnoticed by the experts and to accurately segment the detected polyps during interventions. Although state-of-the-art models are proposed, it remains a challenge to define representations that are able to generalize well and that mediate between capturing low-level features and higher-level semantic details without being redundant. Another challenge with these models is that they are computation and memory intensive, which can pose a problem with real-time applications.

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Introduction: Incontinence is commonly experienced by adults who receive care support in a residential facility or in their own home. These individuals are at risk of developing incontinence-associated dermatitis (IAD), which is caused by prolonged and repeated exposure of the skin to urine or faeces. An IAD manual was developed providing an evidence-based clinical algorithm and an e-learning training programme for the prevention and treatment of IAD.

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Background: Uncomplicated urinary tract infections (uUTIs) are common bacterial infections.

Aim: Evaluate the burden of uUTI in England for 1) potential determinants of disease progression; 2) extent and impact of antimicrobial prescribing non-concordant with treatment guidelines; and 3) economic burden and costs.

Design & Setting: Retrospective cohort study utilising patient data from the Clinical Practice Research Datalink (CPRD) linked to English Hospital Episodes Statistics.

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Forensic facial professionals have been shown in previous studies to identify people from frontal face images more accurately than untrained participants when given 30 s per face pair. We tested whether this superiority holds in more challenging conditions. Two groups of forensic facial professionals (examiners, reviewers) and untrained participants were tested in three lab-based tasks: other-race face identification, disguised face identification, and face memory.

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Substance addiction can be considered a form of social injustice grounded in interactions between individual, family and community-level risk factors. Although prevention and treatment of substance use disorder is a key target of the United Nations sustainable development goal Good Health and Well-Being, many low-and-middle-income countries lack a culturally validated approach for its management. We contend that a resilience approach may provide a sound basis from which to develop such an approach in non-western, low-resource settings.

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Quantifying interseismic deformation of fault networks which are predominantly deforming in a north-south direction is challenging, because GNSS networks are usually not dense enough to resolve deformation at the level of individual faults. The alternative, interferometric synthetic aperture radar (InSAR), provides high spatial resolution but is limited by a low sensitivity to N-S motion. We study the active normal fault network of Western Türkiye, which is undergoing rapid N-S extension, using InSAR.

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The scale of food waste across Europe is alarming, and its reduction is becoming an important public policy and governance issue. Sustainable Development Goal Target 12.3 constitutes a global attempt to galvanize system-level reductions.

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Objective: The objective of this study was to report the 12-month oncological outcomes for patients with non-muscle-invasive bladder cancer (NMIBC) within the prospective, international COVIDSurg Cancer study.

Patients And Methods: Eligible patients were aged ≥18 years and scheduled for elective surgical management of NMIBC with curative intent (transurethral resection of bladder tumour [TURBT] or bladder biopsy) from 21 January to 14 April 2020. The primary outcome was disease recurrence within 12 months of previous elective TURBT/bladder biopsy.

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Indonesia accounts for more than one third of the world's tropical peatlands. Much of the peatland in Indonesia has been deforested and drained, meaning it is more susceptible to fires, especially during drought and El Niño events. Fires are most common in Riau (Sumatra) and Central Kalimantan (Borneo) and lead to poor regional air quality.

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We report the development of peptide-glycosaminoglycan hydrogels as injectable biomaterials for load-bearing soft tissue repair. The hydrogels are injectable as a liquid for clinical delivery, rapidly form a gel , and mimic the osmotic swelling behaviour of natural tissue. We used a new model to demonstrate their application as a nucleus augmentation material for the treatment of intervertebral disc degeneration.

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Article Synopsis
  • Energy-dispersive Laue diffraction (EDLD) is used to analyze the crystalline structure of dental enamel, focusing on how specific salivary peptides (statherin and histatin-1) affect demineralization processes.
  • Three groups of healthy incisors were studied: a control group and two groups pre-treated with salivary peptides before being demineralized, allowing for a comparison of enamel texture.
  • The study found that peptide-treated samples exhibited greater texture variations and multiple orientation populations of hydroxyapatite crystals, highlighting the potential of EDLD for detailed analysis in dental research.
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Highlighting overlooked biodiversity through online platforms: The "Chalcid Wasps of Cyprus" website.

Biodivers Data J

September 2024

Laboratory of Vector Ecology and Applied Entomology, Joint Services Health Unit Cyprus, BFC RAF Akrotiri BFPO 57, Limassol, Cyprus Laboratory of Vector Ecology and Applied Entomology, Joint Services Health Unit Cyprus, BFC RAF Akrotiri BFPO 57 Limassol Cyprus.

Article Synopsis
  • Biodiversity data platforms gather crucial information on native and alien species to support conservation efforts globally.
  • Chalcid wasps, a highly diverse group of insects, serve as effective biological control agents but are under-researched in Cyprus, with many species likely undiscovered.
  • A new online platform, "Chalcid wasps of Cyprus," aims to raise awareness, provide detailed data, and promote conservation for these important insects.
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To develop a core outcome set for Achilles tendinopathy (COS-AT) for use in clinical trials we performed a five-step process including (1) a systematic review of available outcome measurement instruments, (2) an online survey on truth and feasibility of the available measurement instruments, (3) an assessment of the methodological quality of the selected outcome measurement instruments, (4) an online survey on the outcome measurement instruments as COS and (5) a consensus in-person meeting. Both surveys were completed by healthcare professionals and patients. The Outcome Measures in Rheumatology guidelines with a 70% threshold for consensus were followed.

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The Afrotropics are experiencing some of the fastest urbanisation rates on the planet but the impact of city growth on their rich and unique biodiversity remains understudied, especially compared to natural baselines. Little is also known about how introduced species influence β-diversity in these contexts, and how patterns coincide with native ranges of species. Here we investigated how tree assemblages of the endemic-rich Afrotropical island of São Tomé differed between urban, rural and natural zones.

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Biocatalysis in ionic liquids enables novel routes for bioprocessing. Enzymes derived from extremophiles promise greater stability and activity under ionic liquid (IL) influence. Here, we probe the enzyme alcohol dehydrogenase 2 from the halophilic archaeon in thirteen different ion combinations for relative activity and analyse the results against molecular dynamics (MD) simulations of the same IL systems.

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Background: Irritable bowel syndrome (IBS) can cause troublesome symptoms impacting patients' quality of life and incur considerable health service resource use. Guidelines suggest low-dose amitriptyline for IBS as second line treatment, but this is rarely prescribed in primary care.

Aim: To explore patients' and general practitioners' (GPs) views and experiences of using low-dose amitriptyline for IBS.

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Clinical guidance recommends promotion of physical activity during general practice consultations. The frequency and content of physical activity discussions in UK general practice are poorly understood. To explore the content of physical activity discussions during routine consultations between patients and general practitioners (GPs).

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Article Synopsis
  • The study aimed to assess the effectiveness of ECG in detecting cardiac issues in post-hospitalized COVID-19 patients through cardiac magnetic resonance (CMR) imaging.
  • Results showed that these patients had significantly more ECG abnormalities compared to healthy controls, yet both groups had similar levels of CMR abnormalities.
  • Adding additional analyses on repolarization improved ECG's ability to identify patients with CMR abnormalities and reduced the reliance on sex in the diagnostic process.
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Climate change is projected to increase the frequency and intensity of extreme heat events, and may increase humidity levels, leading to coupled thermal and hydric stress. However, how humidity modulates the impacts of heat stress on species and their interactions is currently unknown. Using an insect host-parasitoid interaction: the Indian meal moth, , and its endoparasitoid wasp, , we investigated how humidity interacted with heat stress duration, applied at different host developmental stages, to affect life history traits.

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Article Synopsis
  • International guidelines suggest that surgical removal of suspected localized renal cell carcinoma (RCC) is common, but some benign cases are identified post-surgery, highlighting a need for better non-invasive diagnostic tests.
  • A systematic review was conducted on imaging tests' accuracy for T1 renal tumors, analyzing 27 studies involving over 2000 tumors, which highlighted various imaging modalities like CT, MRI, and PET scans.
  • While [Tc]Tc-sestamibi SPECT/CT showed promising sensitivity and specificity, the optimal imaging strategy remains uncertain, calling for further research and standardization of diagnostic criteria across different imaging techniques.
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