30 results match your criteria: "University of LausanneLausanne[Affiliation]"

Carryover effects of emotions that lead to biases in social judgments are commonly observed. We suggest that such effects may be influenced by the ability to engage or disengage attention from emotional stimuli. We assessed the ability to activate and inhibit attention to anger stimuli, experimentally induced anger in a demanding task, and measured social judgment toward an ambiguous target.

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Electrically-evoked low-frequency (submaximal) force is increased immediately following high-frequency stimulation in human skeletal muscle. Although central mechanisms have been suggested to be the major cause of this low-frequency force potentiation, intramuscular factors might contribute. Thus, we hypothesized that two intramuscular Ca-dependent mechanisms can contribute to the low-frequency force potentiation: increased sarcoplasmic reticulum Ca release and increased myofibrillar Ca sensitivity.

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Basic Values, Career Orientations, and Career Anchors: Empirical Investigation of Relationships.

Front Psychol

September 2017

Department of Work and Organisation Psychology, Institute for Psychology, University of BernBern, Switzerland.

In today's dynamic and uncertain career context, values play an important role for career choice and lifelong career self-management. Values are desirable goals that are sought by individuals to satisfy their needs and are important for understanding career orientations in terms of protean and boundaryless career orientations and career anchors. However, how career orientations or career anchors fit into a well-established and supported model and into the structure of basic human values remains an important and under-investigated question.

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Oxygen uptake ([Formula: see text]) kinetics has been reported to be influenced by the activity mode. However, only few studies have compared [Formula: see text]O kinetics between activities in the same subjects in which they were equally trained. Therefore, this study compared the [Formula: see text]O kinetics response to swimming, arm cranking, and cycling within the same group of subjects within the heavy exercise intensity domain.

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The aim of this paper is to present the family alliance (FA) model, which is designed to conceptualize the relational dynamics in the early family. FA is defined as the coordination a family can reach when fulfilling a task, such as playing a game or having a meal. According to the model, being coordinated as a family depends on four interactive functions: participation (all members are included), organization (members assume differentiated roles), focalization (family shares a common theme of activity), affect sharing (there is empathy between members).

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Heart rate variability (HRV) is non-invasive and commonly used for monitoring responses to training loads, fitness, or overreaching in athletes. Yet, the recording duration for a series of RR-intervals varies from 1 to 15 min in the literature. The aim of the present work was to assess the minimum record duration to obtain reliable HRV results.

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is a major fungal pathogen causing life-threatening diseases in immuno-compromised patients. The efficacy of current drugs to combat infections is limited, as these infections have a 40-60% mortality rate. There is a real need for novel therapeutic approaches, but such advances require a detailed knowledge of and its pathogenesis.

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Innate immune response components such as toll-like receptors (TLRs) and NLRP3-inflammasome act in concert to increase IL-1α/β secretion by synovial macrophages. Previous results suggest that IL-1α/β could be an important mediator involved in the pathogenesis of osteoarthritis (OA). The aim of our study was to evaluate the role of NLRP3, IL-1β, and IL-1α in the menisectomy (MNX) model of murine OA.

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Agricultural industry uses pesticides to optimize food production for the growing human population. A major issue for crops is fungal phytopathogens, which are treated mainly with azole fungicides. Azoles are also the main medical treatment in the management of diseases caused by ubiquitous fungi, such as .

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Antibiotic resistance has become a major health issue. Nosocomial infections and the prevalence of resistant pathogenic bacterial strains are rising steadily. Therefore, there is an urgent need to develop new classes of antibiotics effective on multi-resistant nosocomial pathogenic bacteria.

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This study examined how individual team members adjust their activity to the needs for collective behavior. To do so, we used an enactive phenomenological approach and explored how soccer players' lived experiences were linked to the active regulation of team coordination during eight offensive transition situations. These situations were defined by the shift from defensive to offensive play following a change in ball possession.

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How Energy Metabolism Supports Cerebral Function: Insights from C Magnetic Resonance Studies .

Front Neurosci

May 2017

Laboratory for Functional and Metabolic Imaging, École Polytechnique Fédérale de LausanneLausanne, Switzerland.

Cerebral function is associated with exceptionally high metabolic activity, and requires continuous supply of oxygen and nutrients from the blood stream. Since the mid-twentieth century the idea that brain energy metabolism is coupled to neuronal activity has emerged, and a number of studies supported this hypothesis. Moreover, brain energy metabolism was demonstrated to be compartmentalized in neurons and astrocytes, and astrocytic glycolysis was proposed to serve the energetic demands of glutamatergic activity.

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The increasingly aging population in most industrialized societies, coupled with the rather age-diverse current workforce makes discrimination against older employees a prevalent issue, especially in employment contexts. This renders research on ways for reducing this type of discrimination a particularly pressing concern. Drawing on theories of social identity and impression management, our research examines the role of impression management, aimed at refuting common older worker stereotypes, in diminishing bias against older job applicants during the job interview.

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Soil organic carbon (SOC) is an important and manageable property of soils that impacts on multiple ecosystem services through its effect on soil processes such as nitrogen (N) cycling and soil physical properties. There is considerable interest in increasing SOC concentration in agro-ecosystems worldwide. In some agro-ecosystems, increased SOC has been found to enhance the provision of ecosystem services such as the provision of food.

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Strains of that produce antimicrobial metabolites and control soilborne plant diseases have often been isolated from soils defined as disease-suppressive, i.e., soils, in which specific plant pathogens are present, but plants show no or reduced disease symptoms.

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Postpartum parental depression, even of mild intensity and short duration, has negative consequences on child development, including increased externalizing and internalizing symptoms. Studies revealed that the links between parental depression and child development are mediated by parenting difficulties. On the other hand, the mediating role of problematic family-level relationships, such as low coparenting support and high conflict between the parents, has rarely been considered, although coparenting difficulties have been linked with both increased depressive symptoms in parents and increased symptoms in toddlers.

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Adverse conditions during fetal life have been associated to both structural and functional changes in neurodevelopment from the neonatal period to adolescence. In this study, connectomics was used to assess the evolution of brain networks from infancy to early adolescence. Brain network reorganization over time in subjects who had suffered adverse perinatal conditions is characterized and related to neurodevelopment and cognition.

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Temperature Range Shifts for Three European Tree Species over the Last 10,000 Years.

Front Plant Sci

October 2016

Department of Plant Biology and Ecology, Faculty of Sciences and Technology, University of the Basque Country, UPV/EHULeioa, Spain; IKERBASQUE, Basque Foundation for ScienceBilbao, Spain.

We quantified the degree to which the relationship between the geographic distribution of three major European tree species, and and January temperature (Tjan) has remained stable over the past 10,000 years. We used an extended data-set of fossil pollen records over Europe to reconstruct spatial variation in Tjan values for each 1000-year time slice between 10,000 and 3000 years BP (before present). We evaluated the relationships between the occurrences of the three species at each time slice and the spatially interpolated Tjan values, and compared these to their modern temperature ranges.

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Are There Critical Fatigue Thresholds? Aggregated vs. Individual Data.

Front Physiol

September 2016

Institute of Sport Sciences, University of LausanneLausanne, Switzerland; Department of Physiology, Faculty of Biology and Medicine, University of LausanneLausanne, Switzerland.

The mechanisms underlying task failure from fatiguing physical efforts have been the focus of many studies without reaching consensus. An attractive but debated model explains effort termination with a critical peripheral fatigue threshold. Upon reaching this threshold, feedback from sensory afferents would trigger task disengagement from open-ended tasks or a reduction of exercise intensity of closed-ended tasks.

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The interpolated twitch technique (ITT) is the gold standard to assess voluntary activation and central fatigue. Yet, its validity has been questioned. Here we studied how peripheral fatigue can affect the ITT.

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Glutamate Cysteine Ligase-Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage.

Front Physiol

May 2016

Department of Psychiatry, Centre for Psychiatric Neuroscience, Lausanne University Hospital and University of LausanneLausanne-Prilly, Switzerland; Laboratory of Neuroenergetics and Cellular Dynamics, Brain Mind Institute, Ecole Polytechnique Fédérale de LausanneLausanne, Switzerland; BESE Division, King Abdullah University of Sciences and Technology (KAUST)Thuwal, Saudi Arabia.

Glutathione (GSH) deficits have been observed in several mental or degenerative illness, and so has the metabolic syndrome. The impact of a decreased glucose metabolism on the GSH system is well-known, but the effect of decreased GSH levels on the energy metabolism is unclear. The aim of the present study was to investigate the sensitivity to insulin in the mouse knockout (KO) for the modulatory subunit of the glutamate cysteine ligase (GCLM), the rate-limiting enzyme of GSH synthesis.

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Same Performance Changes after Live High-Train Low in Normobaric vs. Hypobaric Hypoxia.

Front Physiol

May 2016

Faculty of Biology and Medicine, Institute of Sport Sciences, University of LausanneLausanne, Switzerland; Department of Physiology, Faculty of Biology and Medicine, University of LausanneLausanne, Switzerland.

Purpose: We investigated the changes in physiological and performance parameters after a Live High-Train Low (LHTL) altitude camp in normobaric (NH) or hypobaric hypoxia (HH) to reproduce the actual training practices of endurance athletes using a crossover-designed study.

Methods: Well-trained triathletes (n = 16) were split into two groups and completed two 18-day LTHL camps during which they trained at 1100-1200 m and lived at 2250 m (P i O2 = 111.9 ± 0.

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