78,566 results match your criteria: "University of Lausanne & Lausanne University Hospital CHUV[Affiliation]"

A review of predictive modelling and drone remote sensing technologies as a tool for detecting clandestine burials.

Forensic Sci Int

January 2025

School of Criminal Justice, Faculty of Law, Criminal Justice and Public Administration, University of Lausanne, Switzerland.

The search for missing people is a complex and intensive undertaking. Predictive models (such as RAG mapping and geographic profiling) in combination with drone-mounted technologies can improve these searches by driving down time and monetary costs, gathering new types of data and reducing the need for investigators to expose themselves to dangerous environments. Promising technologies to discover traces of clandestine burials in the landscape are LiDAR, RGB photography, multispectral and hyperspectral imaging, as well as infrared/thermal photography.

View Article and Find Full Text PDF

We demonstrate the reversible control of interactions between a local molecular spin, hosted within an iron phthalocyanine (FePc) molecule, and the conduction electrons of a supporting Au(111) surface. Using the tip of a scanning tunneling microscope, we deliberately and reversibly manipulate the adsorption configuration of the molecule relative to the underlying substrate lattice. Different rotation configurations lead to noticeable changes in the differential conductance measured on the FePc molecules.

View Article and Find Full Text PDF

Aim: To assess the perceptions of adults with diabetes regarding their care and health during the COVID-19 pandemic in the canton of Vaud, Switzerland.

Methods: Cross-sectional data was analysed from the 2021 follow-up questionnaire of the CoDiab-VD survey, a cohort of adults living with diabetes in the canton of Vaud. Various aspects of diabetes care and issues relating to the COVID-19 pandemic were assessed.

View Article and Find Full Text PDF

In contrast to blood-oxygenation level-dependent (BOLD) functional MRI (fMRI), which relies on changes in blood flow and oxygenation levels to infer brain activity, diffusion fMRI (DfMRI) investigates brain dynamics by monitoring alterations in the apparent diffusion coefficient (ADC) of water. These ADC changes may arise from fluctuations in neuronal morphology, providing a distinctive perspective on neural activity. The potential of ADC as an fMRI contrast (ADC-fMRI) lies in its capacity to reveal neural activity independently of neurovascular coupling, thus yielding complementary insights into brain function.

View Article and Find Full Text PDF

Background: The combination of cardiovascular disease and diabetes is a highly prevalent condition in the United Arab Emirates. Development and dissemination of evidence-based regional recommendations for optimal screening, treatment and referrals of people with diabetes and high cardiovascular risk is an important priority.

Consensus Panel: An expert panel of diabetologists, endocrinologists and cardiologists from the Emirates Cardiac Society and Emirates Diabetes and Endocrine Society as well as different entities in the UAE, discussed and reviewed evidence and also a consensus report from the American Diabetes Association to formulate contextualized recommendations that could be applied for optimal management of cardiovascular risk in people with diabetes in the UAE.

View Article and Find Full Text PDF

Objective: To explore the correlation between vitamin D levels, related endocrine/metabolic factors, and the risk of slipped capital femoral epiphysis (SCFE) in children and adolescents, and to assess whether vitamin D levels are associated with SCFE severity.

Methods: A retrospective case-control study was conducted from March 2014 to October 2023 in Shengjing hospital. Patients diagnosed with SCFE were categorized as the SCFE group.

View Article and Find Full Text PDF

Purpose: The transoral endoscopic thyroidectomy vestibular approach (TOETVA) is distinguished by its ability to leave no visible scars on the body's surface. Currently, there is still a lack of single-center large sample size analysis on the learning curve of TOETVA, especially for the treatment of thyroid cancer. This study aims to fill this void by presenting a comprehensive analysis of the learning curve and assessing the procedure's feasibility in managing thyroid cancer.

View Article and Find Full Text PDF

Corrigendum: Relationship between vitamin D deficiency and gestational diabetes: a narrative review.

Front Endocrinol (Lausanne)

January 2025

Department of Endocrinology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.

[This corrects the article DOI: 10.3389/fendo.2024.

View Article and Find Full Text PDF

Microstructure of the human metastatic vertebral body.

Front Endocrinol (Lausanne)

January 2025

Department of Industrial Engineering, Alma Mater Studiorum - University of Bologna, Bologna, Italy.

Introduction: Bone spinal metastases disrupt the bone homeostasis, inducing a local imbalance in the bone formation and/or resorption, with consequent loss of the structural optimisation of the vertebrae and increase of the risk of fracture. Little is known about the microstructure of the metastatic tissue, the microstructure of the tissue surrounding the lesion, and how it does compare with vertebrae with no lesions observed on the biomedical images. A comprehensive assessment of the microstructural properties of the entire vertebral body can be obtained with micro computed tomography.

View Article and Find Full Text PDF

Associations of neutrophil/high-density lipoprotein cholesterol ratio with frailty and its mortality.

Front Endocrinol (Lausanne)

January 2025

Department of Medical Intensive Care Unit, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China.

Background: Frailty is an increasingly important determinant in the field of health, and its identification has important clinical significance in the field of critical care medicine. However, there are still a large number of challenges in quick and accurate identification of frailty. This study aims to evaluate the value of the neutrophil/high-density lipoprotein cholesterol ratio (NHR) in frailty and its long-term survival.

View Article and Find Full Text PDF

[This corrects the article DOI: 10.3389/fendo.2023.

View Article and Find Full Text PDF

Background: Gestational diabetes mellitus (GDM) is a common metabolic disorder with important health implications for both mother and offspring. This study aims to assess the relationship between the Triglyceride Glucose (TyG) index and GDM and explore its clinical significance.

Methods: A retrospective cohort study included 631 singleton pregnant women.

View Article and Find Full Text PDF

Background: Gastroparesis following complete mesocolic excision (CME) can precipitate a cascade of severe complications, which may significantly hinder postoperative recovery and diminish the patient's quality of life. In the present study, four advanced machine learning algorithms-Extreme Gradient Boosting (XGBoost), Random Forest (RF), Support Vector Machine (SVM), and -nearest neighbor (KNN)-were employed to develop predictive models. The clinical data of critically ill patients transferred to the intensive care unit (ICU) post-CME were meticulously analyzed to identify key risk factors associated with the development of gastroparesis.

View Article and Find Full Text PDF

Background: Various factors contribute to postoperative delirium (POD) in elderly patients undergoing hip fracture surgeries. Sarcopenia was defined as the progressive loss of skeletal muscle mass and strength associated with aging. The aim of this study was to explore the prevalence of POD and sarcopenia in geriatric patients undergoing hip fracture surgeries and to investigate the correlation between preoperative sarcopenia and POD.

View Article and Find Full Text PDF

Improving students' performance via case-based e-learning.

Front Med (Lausanne)

January 2025

Department of Psychoanalysis and Psychotherapy, Medical University of Vienna, Vienna, Austria.

Background: The integration of interdisciplinary clinical reasoning and decision-making into the medical curriculum is imperative. Novel, high-quality e-learning environments, encompassing virtual clinical and hands-on training, are essential. Consequently, we evaluated the efficacy of a case-based e-learning approach.

View Article and Find Full Text PDF

Objective: To evaluate the effectiveness of integrating GASMAN anesthesia simulation software with case-based learning (IGC) compared to traditional lecture-based learning (LBL) in teaching inhalation anesthesia to undergraduate anesthesiology students.

Methods: Fourth-year students from two academic years (2022, = 110; 2023, = 131) enrolled in a five-year anesthesiology program were assigned to either traditional lecture-based learning (LBL) or IGC groups. The LBL group received traditional lectures using PowerPoint slides, while the IGC group engaged with GASMAN anesthesia simulation software (a tool designed for anesthesia simulation and gas monitoring) combined with case-based learning.

View Article and Find Full Text PDF

Objective: To develop a nomogram model based on the albumin-bilirubin (ALBI) score for predicting the 90-day prognosis of patients with acute-on-chronic liver failure (ACLF) and to evaluate its predictive efficacy.

Methods: Clinical data of 290 ACLF patients at the Third People's Hospital of Nantong City, collected from December 2020 to December 2023, were analyzed. The data were divided into a training set ( = 200) and a validation set ( = 90), with August 2022 as the cut-off date.

View Article and Find Full Text PDF

Background: Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by chronic inflammation and progressive fibrosis. The blood urea nitrogen-to-albumin ratio (BAR) is a comprehensive parameter associated with inflammation status; however, it is unknown whether the BAR can predict the prognosis of IPF.

Methods: This retrospective study included 176 patients with IPF, and 1-year all-cause mortality of these patients was recorded.

View Article and Find Full Text PDF

Improving ADR reporting in Jordan: a qualitative exploration of pharmacists' perspectives.

Front Med (Lausanne)

January 2025

Department of Pharmacy Practice, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.

Background: Community pharmacists are most accessible to patients. Hence, they have a crucial role in ensuring drug safety by detecting and reporting adverse drug reactions (ADRs). However, there may be gaps in their knowledge of ADR reporting systems and barriers they face in reporting.

View Article and Find Full Text PDF

Background: Postoperative gastroparesis syndrome (PGS) is a common postoperative complication characterized by epigastralgia, nausea, and vomiting. Acupuncture is widely used to aid recovery, but its efficacy and safety have not been systematically evaluated.

Method: We retrieved randomized controlled trials (RCTs) using acupuncture as the primary intervention from six databases.

View Article and Find Full Text PDF

Mesenchymal stem cells (MSCs) have shown significant potential in bone regeneration and regenerative medicine in recent years. With the advancement of tissue engineering, MSCs have been increasingly applied in bone repair and regeneration, and their clinical application potential has grown through interdisciplinary approaches involving biomaterials and genetic engineering. However, there is a lack of systematic reviews summarizing their applications in bone regeneration.

View Article and Find Full Text PDF

Proteomics analysis reveals age-related proteins in the urine of chronic kidney disease patients.

Front Med (Lausanne)

January 2025

Department of Nephrology and Institute of Nephrology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Sichuan Clinical Research Center for Kidney Diseases, Chengdu, China.

Chronic kidney disease (CKD) is closely linked to the aging process, making the identification of protein biomarkers that reflect aging in specific organs and tissues crucial for a deeper understanding of this phenomenon. This study aimed to identify potential aging-related proteins present in the urine of CKD patients. Utilizing liquid chromatography-tandem mass spectrometry (LC-MS/MS) proteomic analysis, we identified a total of 1,712 proteins in the urine samples from both healthy controls and CKD patients in our discovery cohort.

View Article and Find Full Text PDF