Identification and Management of Medical Comorbidities in Patients With HR+/HER2- Metastatic Breast Cancer Treated With CDK4/6 Inhibitors: Literature Review and Recommendations From Experts in Spain Opinion.

Approximately one-third of patients with breast cancer have comorbidities at the time of their diagnosis. Recommendations for managing metastatic breast cancer are usually based on the results of clinical trials, which often limit patients with comorbidities. However, comorbidities greatly influence the quality of life, patient survival rate and treatment choice, particularly in older patients.

Long-Term Effects of Ozone Treatment in Patients with Persistent Numbness and Tingling Secondary to Chemotherapy-Induced Peripheral Neuropathy. A Retrospective Study.

Background: Numbness and tingling secondary to chemotherapy-induced peripheral neuropathy (CIPN) are frequent side effects that limit chemotherapy treatment and quality of life. Successful treatments for CIPN are limited. This preliminary report shows the potential long-term effects of ozone treatment in the management of persistent numbness and tingling secondary to CIPN.

Feasibility study of hyperspectral colposcopy as a novel tool for detecting precancerous cervical lesions.

Cervical cancer remains a major global health concern, with a specially alarming incidence in younger women. Traditional detection techniques such as the Pap smear and colposcopy often lack sensitivity and specificity and are highly dependent on the experience of the gynaecologist. In response, this study proposes the use of Hyperspectral Imaging, a pioneering technology that combines traditional imaging with spectroscopy to provide detailed spatial and spectral information.

Bentayga-I: Development of a Low-Cost and Open-Source Multispectral CubeSat for Marine Environment Monitoring and Prevention.

CubeSats have emerged as a promising alternative to satellite missions for studying remote areas where satellite data are scarce and insufficient, such as coastal and marine environments. However, their standard size and weight limitations make integrating remote sensing optical instruments challenging. This work presents the development of Bentayga-I, a CubeSat designed to validate PANDORA, a self-made, lightweight, cost-effective multispectral camera with interchangeable spectral optical filters, in near-space conditions.

Academic and Employment Preferences of Nursing Students at the University of Las Palmas of Gran Canaria: A Cross-Sectional Study.

Background/objectives: It is well known that there are differences in the academic and employment preferences of nursing students once they have completed their undergraduate studies in nursing. These preferences are largely influenced by students' affinity for certain thematic areas over others. Therefore, the objective of this study was to identify the employment and academic preferences of third- and fourth-year Nursing Degree students at the University of Las Palmas de Gran Canaria (ULPGC).

Return to Physical Activity in Individuals with Surgical Stomas: A Scoping Review.

In surgically treated individuals with surgical stomas, the return to physical activity is an indicator of quality of life that reflects their well-being. With the aim of synthesizing the available evidence regarding the return to physical activity in individuals with surgical stomas, a scoping review was developed following the methodological approach of the Joanna Briggs Institute and the Preferred Reporting Items for Systematic reviews and Meta-Analyses for Scoping Reviews criteria. Searches were conducted in Medline (PubMed), Scopus, Web of Science, Cinahl, and Lilacs, as well as the meta-search engines TripDatabase and Epistemonikos, using MeSH terms.

Assessing the hidden dangers of volcanic CO exposure: a critical review of health impacts.

Volcanic eruptions pose significant health risks to inhabitants of affected regions, with volcanic gases, including carbon dioxide (CO), being a notable concern. This review examines the implications of long-term exposure to volcanic CO emissions on public health, highlighting the shift in understanding from acute to chronic health effects. Recent studies have underscored the need to reevaluate the adverse health impacts of CO beyond acute toxicity symptoms.

Correction: Martel-Rodríguez et al. Long-Term Performance of a Hybrid-Flow Constructed Wetlands System for Urban Wastewater Treatment in Caldera de Tirajana (Santa Lucía, Gran Canaria, Spain). 2022, , 14871.

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Clinicopathologic findings and causes of mortality in 100 pet rabbits from the Canary Islands, Spain, 2011-2022.

The European domestic rabbit () is commonly kept as a pet, with increasing popularity among pet owners. Despite the increasing body of information on lagomorph medicine and pathology, comprehensive published compilations of causes of mortality in pet rabbits are limited. We analyzed health disorders, pathology findings, and most probable causes of death in 100 pet rabbits submitted to the Anatomopathological Diagnostic Service of the Veterinary School of the University of Las Palmas de Gran Canaria, Canary Islands, Spain, from 2011 to 2022.

Factors influencing the cruisers in recommending onshore excursions in Gran Canaria.

This paper investigates which elements are the ones that most influence the cruise passenger to recommend the onshore excursions, offering relevant information that could help all stakeholders (cruise firms, local operators, politicians, etc.) to better design/adapt shore excursions to the expectations of the cruise passengers, increasing the positive impact of this activity in the destination. The latter is essential for the existence of a good harmony between the cruise ships visiting a destination and the population living there.

Sky Image Classification Based on Transfer Learning Approaches.

Cloudy conditions at a local scale pose a significant challenge for forecasting renewable energy generation through photovoltaic panels. Consequently, having real-time knowledge of sky conditions becomes highly valuable. This information could inform decision-making processes in system operations, such as determining whether conditions are favorable for activating a standalone system requiring a minimum level of radiation or whether sky conditions might lead to higher energy consumption than generation during adverse cloudy conditions.

New insights into the impact of leachates from in-field collected plastics on aquatic invertebrates and vertebrates.

The impact of leachates from micronized beached plastics of the Mediterranean Sea and Atlantic Ocean on coastal marine ecosystems was investigated by using a multidisciplinary approach. Chemical analysis and ecotoxicological tests on phylogenetically distant species were performed on leachates from the following plastic categories: bottles, pellets, hard plastic (HP) containers, fishing nets (FN) and rapido trawling rubber (RTR). The bacteria Alivibrio fischeri, the nauplii of the crustaceans Amphibalanus amphitrite and Acartia tonsa, the rotifer Brachionus plicatilis, the embryos of the sea urchin Paracentrotus lividus, the ephyrae of the jellyfish Aurelia sp.

The effects of climate extreme events on selected food crop yields in Sub-Saharan Africa.

The agricultural sector is essential for economic growth. However, agricultural performance can be limited by factors such as climatic risks. This paper aims to analyse the effect of climate extreme events on selected food crop yield in sub-Saharan Africa (SSA).

A pilot study on gamified and conventional e-quizzes reinforcing human histology among first-year medical and physiotherapy students.

The present retrospective, descriptive, and quasi-experimental study aimed to explore students' perceptions of traditional teaching combined with gamified and nongamified e-tests for postlecture reinforcement. Midterm knowledge retention and academic performance were also analyzed. The study was conducted from February 2021 to May 2022, involving a single group of first-year medical and physiotherapy students enrolled in equivalent core subjects on human histology at the University of Las Palmas de Gran Canaria (ULPGC).

Reptile Identification for Endemic and Invasive Alien Species Using Transfer Learning Approaches.

The Canary Islands are considered a hotspot of biodiversity and have high levels of endemicity, including endemic reptile species. Nowadays, some invasive alien species of reptiles are proliferating with no control in different parts of the territory, creating a dangerous situation for the ecosystems of this archipelago. Despite the fact that the regional authorities have initiated actions to try to control the proliferation of invasive species, the problem has not been solved as it depends on sporadic sightings, and it is impossible to determine when these species appear.

Venturi Injector Optimization for Precise Powder Transport for Directed Energy Deposition Manufacturing Using the Discrete Element Method and Genetic Algorithms.

Additive manufacturing technologies such as directed energy deposition use powder as their raw material, and it must be deposited in a precise and controlled manner. Venturi injectors could be a solution for the highly precise transport of particulate material. They have been studied from different perspectives, but they are always under high-pressure conditions and mostly fed by gravity.

Health impact of the Tajogaite volcano eruption in La Palma population (ISVOLCAN study): rationale, design, and preliminary results from the first 1002 participants.

Background: The eruption of the Tajogaite volcano began on the island of La Palma on September 19, 2021, lasting for 85 days. This study aims to present the design and methodology of the ISVOLCAN (Health Impact on the Population of La Palma due to the Volcanic Eruption) cohort, as well as the preliminary findings from the first 1002 enrolled participants.

Methods: A prospective cohort study was conducted with random selection of adult participants from the general population, with an estimated sample size of 2600 individuals.

Exploring Omega-3's Impact on the Expression of Bone-Related Genes in Meagre ().

Dietary supplementation with Omega-3 fatty acids seems to promote skeletal health. Therefore, their consumption at imbalanced or excessive levels has offered less beneficial or even prejudicial effects. Fish produced in aquaculture regimes are prone to develop abnormal skeletons.

The influence of supervisor supportive behaviors on subordinate job satisfaction: the moderating effect of gender similarity.

This paper analyses the influence that different supervisor supportive behaviors have on subordinate job satisfaction, while considering the gender of individuals involved (supervisor and subordinate). The empirical evidence provided by a sample of 29,833 subordinates from 35 European countries collected by Eurofound through the European Working Condition Survey allows us to assert the following. First, subordinate job satisfaction depends on their perceptions about the supportive behaviors provided by their supervisors in terms of respect, giving recognition for a job well done, coordinating work, helping get the job done, and encouraging the professional development of the subordinate.