2,028 results match your criteria: "University of La Reunion & University Paris Diderot[Affiliation]"

Biological nitrogen fixation is a fundamental part of ecosystem functioning. Anthropogenic nitrogen deposition and climate change may, however, limit the competitive advantage of nitrogen-fixing plants, leading to reduced relative diversity of nitrogen-fixing plants. Yet, assessments of changes of nitrogen-fixing plant long-term community diversity are rare.

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  • A study conducted in France during the 2023-24 RSV season analyzed the effectiveness of nirsevimab, a monoclonal antibody, in preventing RSV infections in infants, focusing on breakthrough cases.
  • Out of 695 RSV-infected infants, researchers sequenced the full-length RSV genome of 545 infants, identifying that 48% had breakthrough infections despite receiving nirsevimab.
  • While no resistance was found in RSV-A infections from nirsevimab-treated infants, two cases of RSV-B showed substitutions linked to resistance, indicating a potential concern for the antibody's effectiveness against this variant.
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Invasive fungal infections are a serious complication for haematology patients. However, there is no study on this subject in Reunion Island. The aim of this study was to estimate the incidence of invasive fungal infections in patients with haematological malignancies at the University Hospital of Reunion Island.

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  • * This study analyzed cases of C bantiana infections in France and its territories, involving patients who were diagnosed through a comprehensive surveillance program, focusing on survival rates and the presence of central nervous system (CNS) involvement.
  • * Out of 23 patients identified from 2002 to 2022, 65% had CNS involvement, with a notable increase in cases reported in 2022, indicating a possible correlation with environmental factors like rising temperatures.
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We report high-quality genomes of three strains of pv, the causal agent of mango bacterial canker disease, including the pathotype strain of this pathovar and two strains from Burkina Faso that emerged a decade ago. These strains hosted two to three plasmids of sizes ranging from 19 to 86 kb. Genome mining revealed the presence of several secretion systems and effectors involved in the virulence of xanthomonads with (i) a type I secretion system of the hlyDB group; (ii) and type II secretion systems; (iii) a type III secretion system with several type III effectors, including transcription activator-like effectors; (iv) several type IV secretion systems associated with plasmid or integrative conjugative elements mobility; (v) three type V secretion system subclasses (Va, Vb, and Vc); and (vi) a single i3* type VI secretion system.

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  • * The Ne/Nc ratio varies due to ecological and evolutionary factors, influencing conservation strategies, and different types of effective population sizes must be considered to grasp their implications.
  • * Despite technological advancements in marine species documentation, predicting the Ne/Nc ratio remains challenging, highlighting the need for more research to effectively manage genetic diversity and population viability in these fish populations.
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Competitive antagonistic action of laccase between species and the newly identified wood pathogenic .

Front Microbiol

September 2024

Chongqing Key Laboratory of Plant Environmental Adaptations, College of Life Science, Chongqing Normal University, Chongqing, China.

, a well-known genus in the Ganodermataceae family, has caused the extinction of several tree species due to its pathogenicity. This study explored the pathogenic effect of a newly identified species on trees and its competitive efficiency against species. sp.

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El Niño typically induces cooling in the Southwest Pacific Ocean during austral summers, usually leading to decreased marine heatwave frequency and severity. However, the 2016 extreme El Niño unexpectedly coincided with the longest and most extensive marine heatwave ever recorded in the region. This heatwave, spanning over 1.

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  • The study investigates the effectiveness of an automated algorithm for measuring intracranial blood volume to predict complications like delayed cerebral ischemia (DCI) and acute hydrocephalus (AH) in patients with aneurysmal subarachnoid hemorrhage (aSAH).
  • It compares the algorithm's predictive accuracy using the area under the receiver operating characteristic curve (ROC) against eight established radiological scales.
  • Results from 145 patients indicate that the algorithm performs similarly to existing scales in predicting DCI and AH, with significant correlations found, particularly with the Hijdra scale for cisternal blood volume.
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[Not Available].

CMAJ

October 2024

Division d'immunologie clinique et d'allergie (Jeimy, Yu), Départment de médecine, Western University, London, Ont.; Division des allergies (Chan, Cook), Département de pédiatrie, University of British Columbia, BC Children's Hospital, Vancouver, C.-B.

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Protection efforts have resulted in ~10% of existing fish biomass on coral reefs.

Proc Natl Acad Sci U S A

October 2024

Thriving Oceans Research Hub, School of Geosciences, University of Sydney, Camperdown, NSW 2006, Australia.

The amount of ocean protected from fishing and other human impacts has often been used as a metric of conservation progress. However, protection efforts have highly variable outcomes that depend on local conditions, which makes it difficult to quantify what coral reef protection efforts to date have actually achieved at a global scale. Here, we develop a predictive model of how local conditions influence conservation outcomes on ~2,600 coral reef sites across 44 ecoregions, which we used to quantify how much more fish biomass there is on coral reefs compared to a modeled scenario with no protection.

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Recommendations of an expert group for the cardiac assessment of non-dystrophic myotonia adult patients treated with mexiletine.

Neuromuscul Disord

November 2024

Cardiology Department, CHU de Caen, UR 4650 Unicaen, Avenue de la Côte de Nacre CS 30001, 14033 Caen France.

Mexiletine (NaMuscla™) is indicated for the symptomatic treatment of myotonia in adults with non-dystrophic myotonia. A cardiac assessment is required as mexiletine may have a pro-arrhythmic effect. Long-term safety data supporting the use of mexiletine in patients with non-dystrophic myotonia combined with the extensive clinical experience of an expert group resulted in creation of an algorithm for cardiac monitoring of patients treated with mexiletine.

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  • This study explores how Graves' orbitopathy (GO) is managed across 26 medical centers in France, focusing on the structure and availability of treatment services.
  • Researchers contacted 28 centers to gather data through a questionnaire about multidisciplinary meetings, dedicated services, and treatment methods.
  • The findings revealed that while a majority have dedicated services and utilize first-line treatments like intravenous corticosteroids, there’s significant variability in practices, highlighting the need for standardization and improving accessibility to new treatments like tocilizumab and teprotumumab.
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  • Human activities and climate change are harming the oceans, causing a big drop in the variety of plants and animals found in coastal areas.
  • The study looks at how pollution affects juvenile green sea turtles on La Réunion Island, focusing on the chemicals they pick up and how it impacts their health.
  • Researchers found that different turtle body parts had different levels of metal contamination, and they suggested new ways to monitor turtle health to help protect them in the future.
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  • Sickle cell disease (SCD) affects many people worldwide, and a serious issue related to it is called acute chest syndrome (ACS), which can make patients really sick and require hospitalization.
  • Researchers studied data from 1998 to 2022 about young people with SCD who needed a special treatment called ECMO to help their lungs.
  • They found that 55.8% of patients survived ECMO treatment, but there were complications, and not all patients, especially young kids and some adults, survived when ECMO was used for heart resuscitation.
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Purpose: This research investigated the pre-, per- and post cooling strategies used by competitive tennis players from various levels of play who occasionally train and compete in hot (>28°C) and humid (>60% rH), and dry (<60% rH) environments.

Methods: 129 male tennis players (M = 24.9) competing at regional ( = 54), national ( = 30) and international ( = 45) levels, completed an online questionnaire regarding their use (i.

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Emerging and reemerging fungal infections are very common in nosocomial and non-nosocomial settings in people having poor immunogenic profiles either due to hematopoietic stem cell transplants or are using immunomodulators to treat chronic inflammatory disease or autoimmune disorders, undergoing cancer therapy or suffering from an immune weakening disease like HIV. The refractory behavior of opportunistic fungi has necessitated the discovery of unconventional antifungals. The emergence of black fungus infection during COVID-19 also triggered the antifungal discovery program.

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Introduction: The Fat Mass and Obesity-Associated () gene encodes a demethylase, which modulates RNA N6-methyladenosine (m6A) and plays a regulatory role in adipocyte differentiation and the pathogenesis of human obesity.

Methods: To understand the potential role of in osteoporosis (OP), we investigated five single nucleotide variations (SNVs) in intron 1 (rs8057044, rs8050136, rs9939609, rs62033406, and rs9930506) of the gene, and a missense SNV i.e.

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Sperm Storage and Use Following Multiple Insemination in Encouraging Insights for the Sterile Insect Technique.

Insects

September 2024

Polo d'Innovazione Genomica, Genetica e Biologia (PoloGGB), Via San Andrea delle Fratte, 06132 Perugia, Italy.

The key to success in the application of the sterile insect technique (SIT) relies on the ability of released, sterile males to outcompete their fertile wild male counterparts to mate with wild females. However, many insect species exhibit multiple-mating behavior, which can be a way for females to select paternity for their progeny. This study aims to recognize the consequences of potential double-matings during an SIT program and to detect any evidence of sperm selection favoring sperm from fertile mates.

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The Potential of Human Pulmonary Mesenchymal Stem Cells as Vectors for Radiosensitizing Metallic Nanoparticles: An In Vitro Study.

Cancers (Basel)

September 2024

Laboratoire Interdisciplinaire de Recherche en Santé (LIRS), RunResearch, Sainte-Clotilde Clinic, 127 Route de Bois de Nèfles, 97400 Saint-Denis, Reunion Island, France.

Article Synopsis
  • Metallic nanoparticles (NPs), specifically core-shell FeO@Au NPs, were evaluated for their effects on human pulmonary mesenchymal stem cells (HPMSCs), showing no impact on cell viability at a concentration of 100 µg/mL.
  • Gene expression in HPMSCs was altered after exposure, with significant changes noted at 72 hours, including decreased proinflammatory cytokines, but no effects on certain key tumor-related gene expressions.
  • The study concluded that FeO@Au NPs do not harm HPMSCs and may be a promising method for targeted delivery to tumors alongside radiation therapy.
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Integrative taxonomy clarifies the evolution of a cryptic primate clade.

Nat Ecol Evol

January 2025

Centre de Recherche sur la Biodiversité et l'Environnement (CRBE), UMR5300 Université Toulouse, CNRS, IRD, Toulouse INP, Université Toulouse 3 Paul Sabatier (UT3), Toulouse, France.

Article Synopsis
  • * The article proposes a comprehensive approach to accurately define species boundaries, using integrated evidence and focusing on geographic isolation, specifically applied to the mouse lemurs, a debated group of primates.
  • * The study reveals that previous estimates of species diversity were inflated, mainly mistaking geographic variation for new species, and suggests that a clearer understanding of species limits can inform better conservation strategies.
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[How do women in Réunion Island want to perform HPV test on vaginal sampling as part of cervical cancer screening?].

Gynecol Obstet Fertil Senol

September 2024

UFR santé, université de la Réunion, 40, avenue de Soweto, Terre-Sainte, BP 373, 97455 Saint-Pierre cedex, Réunion; Service de gynécologie-obstétrique, centre hospitalier universitaire Sud-Réunion, BP 350, 97448 Saint-Pierre cedex, Réunion; Inserm, CIC 1410, Reunion University Hospital, 97448 Saint-Pierre, Réunion. Electronic address:

Article Synopsis
  • A study in La Reunion examined women's preferences for vaginal sampling (VS) for HPV testing as part of cervical cancer (CC) screening, focusing on women aged 30 to 65 who were concerned about their screening status.
  • A total of 202 women participated, with results showing that many preferred to collect the sampling kit from a healthcare provider but also favored self-sampling (SS) at home, with clear instructions provided in French and visual aids.
  • The findings indicated no significant difference in preferences between women who were up to date on screenings versus those who were not, suggesting a potential need for further research on the implementation of self-sampling for a broader population.
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Marine Microorganism Molecules as Potential Anti-Inflammatory Therapeutics.

Mar Drugs

September 2024

Group Bioactivities of Natural Compounds and Derivatives (BIONA), Institut Pasteur of New Caledonia, Member of the Pasteur Network, Noumea 98845, New Caledonia.

The marine environment represents a formidable source of biodiversity, is still largely unexplored, and has high pharmacological potential. Indeed, several bioactive marine natural products (MNPs), including immunomodulators, have been identified in the past decades. Here, we review how this reservoir of bioactive molecules could be mobilized to develop novel anti-inflammatory compounds specially produced by or derived from marine microorganisms.

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The use of propionic and lactic acid bacteria to produce cobalamin and folate in injera, an Ethiopian cereal-based fermented food.

Int J Food Microbiol

January 2025

QualiSud, Université de Montpellier, Avignon Université, CIRAD, Institut Agro, IRD, Université de la Réunion, 911 avenue Agropolis, 34394 Montpellier Cedex, France. Electronic address:

Like in many developing countries, the traditional Ethiopian diet relies mainly on starchy staple foods and often lacks sufficient animal-sourced foods which are crucial for cobalamin intake. Furthermore, the concentration of folate in traditionally prepared injera, an Ethiopian cereal-based fermented staple food, is highly variable and injera contains biologically inactive corrinoids. This study aimed to improve the cobalamin and folate content of injera by using cobalamin-producing Propionibacterium freudenreichii and folate-producing Lactiplantibacillus plantarum strains, both individually and combined.

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