2 results match your criteria: "University of Kragujevac and Clinical Center Kragujevac[Affiliation]"
Bucindolol for the Maintenance of Sinus Rhythm in a Genotype-Defined HF Population: The GENETIC-AF Trial.
JACC Heart Fail
July 2019
Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Objectives: The purpose of this study was to compare the effectiveness of bucindolol with that of metoprolol succinate for the maintenance of sinus rhythm in a genetically defined heart failure (HF) population with atrial fibrillation (AF).
Background: Bucindolol is a beta-blocker whose unique pharmacologic properties provide greater benefit in HF patients with reduced ejection fraction (HFrEF) who have the beta-adrenergic receptor (ADRB1) Arg389Arg genotype.
Methods: A total of 267 HFrEF patients with a left ventricular ejection fraction (LVEF) <0.
The impact of cardiovascular drugs on the efficacy of local anesthesia in dentistry.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
December 2016
Department of Pharmacology, Faculty of Medical Sciences, University of Kragujevac and Clinical Center Kragujevac, Serbia.
Background And Aim: Drugs used chronically by patients with diseases of the cardiovascular system (group C of the ATC classification) may act on adrenergic receptors and/or certain ion channels, which gives them the potential to interact with the action of local dental anesthetics. The aim of the study was to investigate the effect of systemically administered chronic cardiovascular medication (oral route) on the efficacy of intraoral local anesthesia in patients with diseases of the cardiovascular system.
Patients And Methods: This was a prospective cohort study which analyzed the efficacy of local terminal anesthesia (onset of anesthesia, duration anesthetized area) in the upper jaw of 70 patients: 40 patients on medication for cardiovascular system disorders and 30 patients who were not using these drugs (the control group).