Half logistic exponentiated inverse Rayleigh distribution: Properties and application to life time data.

This paper presents a novel extension of the exponentiated inverse Rayleigh distribution called the half-logistic exponentiated inverse Rayleigh distribution. This extension improves the flexibility of the distribution for modeling lifetime data for both monotonic and non-monotonic hazard rates. The statistical properties of the half-logistic exponentiated inverse Rayleigh distribution, such as the quantiles, moments, reliability, and hazard function, are examined.

Tungsten disulphide nanosheet modulated fluorescent gold nanocluster immunoprobe for the detection of tau peptide: Alzheimer's disease biomarker.

The neuronal tau peptide serves as a key biomarker for neurodegenerative diseases, specifically, Alzheimer's disease, a condition that currently has no cure or definitive diagnosis. The methodology to noninvasively detect tau levels from body fluids remains a major hurdle for a rapid and simple diagnostic approach. Thus, developing new detection methods for sensing tau protein levels is crucial.

Design of Fluorescence Enhancing Sensor for Mercury Detection via Bamboo Cellulose-Derived Carbon Dots.

Mercury contamination of the environment is extremely hazardous to human health because of its significant toxicity, especially in water. Biomass-derived fluorophores such as carbon dots (CDs) have emerged as eco-friendly and cost-effective alternative sensors that provide comparable efficacy while mitigating the environmental and economic drawbacks of conventional methods. In this work, we report the fabrication of a selective fluorescence-enhancing sensor based on sulfur-doped carbon dots (SCDs) using waste bamboo-derived cellulose and sodium thiosulfate as the soft base dopant, which actively complexes with mercury ions for detection.

NiCr-LDH/VC MXene nanocomposites as an efficient electrocatalyst for urea oxidation.

The quest for highly efficient electrocatalysts for direct urea fuel cells (DUFCs) is vital in addressing the energy deficits and environmental crisis. Ni-based LDHs are widely known for their substantial capability in urea oxidation reactions (UOR). This study involved the synthesis of NiCr-LDH/VC MXene nanocomposites (NCVs) and the evaluation of their electrochemical efficiency towards UOR.

Magnetoelectric properties and Morin type spin transitions of Na-doped GaFeO.

The effects of Na doping on the structure magnetic, electric, and magnetoelectric properties of GaFeOwere studied. Rietveld refinement of the XRD data reveals the formation of a single-phase trigonal structure with no impurity on Na doping up to 50% and a significant increase in lattice strain with doping. FTIR and Raman analysis further supported the phase purity of the samples.

1,3,5-Triformylphloroglucinol Derived β-Ketoenamine-Linked Functional Covalent Organic Frameworks with Enhanced Crystallinity and Stability-Recent Advances.

Crystallinity, stability, and complexity are significant factors to consider in the design and development of covalent organic frameworks (COFs). Among various building blocks used, 1,3,5-triformylphloroglucinol (Tp) is notable for enhancing both crystallinity and structural stability in COFs. Tp facilitates the formation of β-ketoenamine-linked COFs through keto-enol tautomerism when reacted with aromatic amines.

Engineering the multifunctionality of LiYTeO garnets with Sm and Tb activators for solid-state lighting and luminescence thermometry.

Tuning the photophysical response is indispensable in realizing the full potential of phosphors to meet the demands of multifunctional applications, such as solid-state lighting and optical thermometry. Herein, orange-red emission from an Sm-based LiYTeO system was studied for the first time with CIE coordinates of (0.488, 0.

Spatiotemporal dynamics of carbon isotope ratios and phytoplankton composition in the eastern Arabian Sea.

This study investigated major contributors of the particulate organic matter (POM) using stable isotope ratios of particulate organic carbon (δC) and its relationship with phytoplankton composition during three seasons across six coast-offshore transects in the eastern Arabian Sea (EAS). Results revealed significant spatiotemporal variations, with elevated δC in coastal waters during the winter and summer monsoon (-22.40 ± 1.

Bovine Serum Albumin-Capped Fluorescent Copper Nanocluster Incorporated with 2D-Molybdenum Disulfide Nanosheets as a FRET-Based Immune Probe for the "Turn-On" Detection of cTnT.

Cardiovascular disease is the primary cause of mortality worldwide, as stated by the World Health Organization. We utilized the red fluorescence emitted by copper nanoclusters (CuNCs) to detect cardiac Troponin T (cTnT). We designed a fluorescent probe to detect cTnT using an on-off-on technique.

Sensing the Future-Frontiers in Biosensors: Exploring Classifications, Principles, and Recent Advances.

Biosensors are transforming healthcare by delivering swift, precise, and economical diagnostic solutions. These analytical instruments combine biological indicators with physical transducers to identify and quantify biomarkers, thereby improving illness detection, management, and patient surveillance. Biosensors are widely utilized in healthcare for the diagnosis of chronic and infectious diseases, tailored treatment, and real-time health monitoring.

Damage mechanisms of bisphenols on the quality of mammalian oocytes.

The extensive use of bisphenols in the plastics industry globally is a major growing concern for human health. Bisphenol compounds are easily leached out from plastic containers to food, beverages, and drinking water and contaminate the natural environment. Daily exposure of bisphenol compounds increases their load and impairs various organs, including the reproductive system.

Efficacy of Arogya Rakshak Panchatantra (Five Lifestyle Principles) on Heart Rate Variability and Menstrual Symptoms in Primary Dysmenorrhea: A Randomized Controlled Trial.

Primary dysmenorrhea (PD) is associated with decreased performance and reduced quality of life in young adults. This study aims to evaluate the effectiveness of implementing Arogya Rakshak Panchatantra (ARP), a naturopathic lifestyle practice, among young female adults with PD. This open-label, parallel-arm, randomized controlled trial included 52 young female adults with PD aged between 16 and 25 years.

Red emitting fluorescence sensor based on Eu-tungstate complex for the detection of bilirubin in biological fluid.

Bilirubin is an important biomarker indicative of human health metabolism, especially in jaundice disease. In this work, we develop an Eu (Europium)-tungstate complex-based turn-off luminescence detection method for bilirubin in human (urineand serum)samples. The Eu-tungstate complex was synthesized by a straightforward one-pot procedure at ambient temperature, utilizing Europium chloride and Sodium tungstate as the precursors.

End Binding Proteins: Drivers of Cancer Progression.

Cancer, a complex and heterogeneous disease, continues to be a major global health concern. Despite advancements in diagnostics and therapeutics, the aggressive nature of certain cancers remain a significant challenge, necessitating a deeper understanding of the underlying molecular mechanisms driving their severity and progression. Cancer severity and progression depend on cellular properties such as cell migration, cell division, cell shape changes, and intracellular transport, all of which are driven by dynamic cellular microtubules.

Synergistically stabilized SAPO-37-tetragonal zirconia composites: a promising catalyst for ethyl levulinate synthesis.

A tetragonal zirconia-faujasitic SAPO-37 zeolite composite (SAP-37ZR) was synergistically stabilised at 550 °C using a temperature programmed reduction method. The presence of the zeolite-ZrO composite phase was confirmed through powder XRD reflection, SEM and TEM-ED pattern analyses. The developed SAP-37ZR composite, exhibiting moderate acidity, was found to be highly active for the production of ethyl levulinate (EL) from furfuryl alcohol with a 99% yield.

Differentially Expressed Genes (DEGs) in Umbelliferone (UMB) Producing Endophytic Fusarium oxysporum (ZzEF8) Following Epigenetic Modification.

Despite several studies documenting secondary metabolite (SM) production by endophytes, their commercial use is often limited owing to the research lacunae in the underlying biosynthetic pathway and the corresponding metabolic flux. Combining epigenetic modulation with RNA-Seq analysis constitutes a promising approach for inducing regulatory gene(s) and thereby identifying their role in SM biosynthesis. Our earlier studies had identified the hypomethylating effects of prednisone in umbelliferone (UMB) (7-hydroxyl coumarin) producing endophytic Fusarium oxysporum isolate, ZzEF8 isolated from Zingiber zerumbet rhizomes.

Toxin production in bloom-forming, harmful alga Alexandrium pacificum (Group IV) is regulated by cyst formation-promoting bacteria Jannaschia cystaugens NBRC 100362.

Harmful algal blooms (HABs) caused by dinoflagellates like Alexandrium pacificum pose significant ecological and public health risks due to their production of paralytic shellfish toxins (PSTs). Bacterial populations, particularly Alexandrium cyst formation-promoting bacteria (Alex-CFPB), are known to significantly influence growth, encystment, toxin synthesis, the composition of toxic components, and bloom dynamics of these dinoflagellates. However, the role of Alex-CFPB in Alexandrium toxin synthesis and the mechanisms thereof are still unclear.

Quantum dot-to-dye-based fluorescent ratiometric immunoassay for GFAP: a biomarker for ischaemic stroke and glioblastoma multiforme.

Ischaemic stroke and glioma, as leading causes of mortality and long-term disability, pose critical challenges to healthcare systems, necessitating innovative approaches to enable early and cost-effective diagnosis for timely intervention. Glial fibrillary acidic protein (GFAP), an astrocyte-produced protein, is highly responsive to both ischaemic stroke and glioblastoma multiforme, with its levels correlating to the extent of brain damage. In this study, we present the development of an immunoassay probe for the ratiometric fluorescent detection of glial fibrillary acidic protein (GFAP), employing a monoclonal GFAP antibody-conjugated silicon quantum dots (Ab@SiQDs) and rhodamine B dye (RhB)-based immunoprobe.

Anatomical adaptations of mangroves to the intertidal environment and their dynamic responses to various stresses.

Mangroves are intertidal plants that survive extreme environmental conditions through unique adaptations. Various reviews on diverse physiological and biochemical stress responses of mangroves have been published recently. However, a review of how mangroves respond anatomically to stresses is lacking.

An AI-Driven Framework for Detecting Bone Fractures in Orthopedic Therapy.

This study presents an advanced artificial intelligence-driven framework designed to enhance the speed and accuracy of bone fracture detection, addressing key limitations in traditional diagnostic approaches that rely on manual image analysis. The proposed framework integrates the YOLOv8 object detection model with a ResNet backbone to combine robust feature extraction and precise fracture classification. This combination effectively identifies and categorizes bone fractures within X-ray images, supporting reliable diagnostic outcomes.

On the differences between the two widely distributed and closely related rock shrimps Sicyonia japonica Balss, 1914 and S. parajaponica Crosnier, 2003 (Dendrobranchiata, Penaeoidea, Sicyoniidae), with a new record of S. japonica from Taiwan.

The rock shrimp Sicyonia japonica Balss, 1914 is recorded from Taiwan for the first time. The availability of many fresh specimens of S. japonica and S.

A new species of Uropeltis Cuvier, 1829 (Serpentes: Uropeltidae) from the eastern escarpment of the southern Western Ghats, India.

A new species of the uropeltid ('shieldtail') snake genus Uropeltis is described based on eight specimens from the southern part of peninsular India's Western Ghats. Uropeltis caudomaculata sp. nov.

Modes of Binding of Small Molecules Dictate the Interruption of RBD-ACE2 Complex of SARS-CoV-2.

The spike protein is a vital target for therapeutic advancement to inhibit viral entrance. Given that the connection between Spike and ACE2 constitutes the initial phase of SARS-CoV-2 pathogenesis, obstructing this interaction presents a promising therapeutic approach. This work aims to find compounds from DrugBank that can modulate the stability of the spike RBD-ACE2 protein-protein complex.