Effectiveness and tolerability of every-other-day rosuvastatin dosing in patients with prior statin intolerance.

Background: Statins are generally well tolerated, but some patients discontinue therapy secondary to adverse effects. Dosing a statin (rosuvastatin) every other day (EOD) may provide significant lipoprotein changes while avoiding common adverse effects in this statin-intolerant population.

Objective: To determine the effect and tolerance of EOD rosuvastatin in patients previously intolerant to statin therapy.