Isolation of a transposable element from Neurospora crassa.

A Neurospora crassa strain from Adiopodoumé, Ivory Coast, contains multiple copies of a transposable element, Tad. The element was detected as a 7-kilobase insertion in two independently isolated spontaneous forward mutants of the am (glutamate dehydrogenase) gene. Laboratory strains do not contain Tad.

The polymorphic phase behavior of dielaidoylphosphatidylethanolamine. Effect of n-alkanols.

The polymorphic phase behavior of dielaidoylphosphatidylethanolamine (DEPE) has been investigated using spectrophotometry and 31P nuclear magnetic resonance (NMR). It has been demonstrated that the bilayer to inverted hexagonal phase transition can be observed by spectrophotometry. The effects of the methanol, ethanol, and propanol on both the gel to liquid crystal transition and the bilayer to inverted hexagonal transition were investigated by spectrophotometry.

Effect of neurotensin on pancreatic and gastric secretion and growth in rats.

Plasma levels of neurotensin are increased by ingestion of fat, making this peptide a candidate for mediation of pancreatic adaptation to dietary fat. We examined the effects of doses of neurotensin on pancreatic secretion and growth to determine whether doses stimulating secretion also increased pancreatic growth and lipase content in rats. Because neurotensin inhibits gastric secretion in other species, we also measured its effects on gastric secretion and growth.

THE CHLORIDE CONTENT OF THE TISSUES OF THE DOG AFTER EXPERIMENTAL GASTROINTESTINAL TRACT OBSTRUCTION.

Comparative observations are reported on the chloride content of the blood, liver, and muscle of the dog after obstruction of the upper gastrointestinal tract. After obstruction of the pylorus there is a marked fall in the chloride content of the liver, and a slight fall in the muscle. Similar changes are observed after obstruction of the jejunum.

THE VISCOSITY OF THE BLOOD OF THE DOG AFTER OBSTRUCTION OF THE UPPER GASTROINTESTINAL TRACT.

Estimations of the viscosity of the whole blood and plasma of the dog after experimental upper gastrointestinal tract obstruction are reported. With cardiac obstruction there is a rapid and marked rise in the viscosity of the whole blood and some increase in the viscosity of the plasma. The changes after pyloric obstruction are similar to those observed after cardiac obstruction.

THE RATE OF REGENERATION OF BLOOD PLATELETS.

By repeatedly withdrawing, defibrinating, and reinjecting blood, the platelet count in dogs can be reduced to an extremely low level. When the reduction in platelets and fibrinogen has been carried to an extreme degree the animals display a marked tendency to bleed. The regeneration of platelets after their removal by defibrination is remarkably rapid and amounts, on an average, to about one fifth of the entire number in the blood per day.