1 results match your criteria: "University of Iowa College of Medicine and the Veterans Administration Medical Center[Affiliation]"
Selective leptin resistance: a new concept in leptin physiology with cardiovascular implications.
J Hypertens
July 2002
Hypertension Genetics Specialized Center of Research, the Department of Internal Medicine, University of Iowa College of Medicine and the Veterans Administration Medical Center, Iowa City, Iowa, USA.
Article Synopsis
- Leptin is a hormone produced by fat cells that helps regulate appetite and metabolism, aiming to reduce body weight.
- Chronic high levels of leptin can lead to increased sympathetic activity and higher blood pressure, particularly in obese individuals.
- The idea of selective leptin resistance suggests that while some obese individuals can't effectively use leptin to suppress hunger and lose weight, they still experience heightened sympathetic responses, potentially leading to hypertension.