128 results match your criteria: "University of Insubria School of Medicine[Affiliation]"

Uncomplicated Type B Aortic Dissection - A European Multicentre Cross-Sectional Evaluation.

Ann Vasc Surg

December 2024

Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Centre Essen, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany.

Objectives: A multicentre European randomized control trial - European Uncomplicated Type B Aortic Repair (EU-TBAR) is being developed to compare pre-emptive TEVAR with custom-made devices vs conventional OMT. The pre-trial set-up is confluent on different pillars, including evaluation of 1) European activity, trends, and governance, 2) outcome reporting, and 3) cost evaluation. This article aimed to demonstrate the observational cross-sectional survey results from participating centres and highlight the risk assessment, activity, practices, and governance of uncomplicated type B aortic dissection (uTBAD).

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Outcomes of Endovascular Repair for Ascending Aortic Diseases: A Systematic Review and Meta-analysis.

Eur J Vasc Endovasc Surg

November 2024

Cardiac Surgery Unit, Cardiac Surgery Division, Department of Cardiovascular Disease "E. Malan", IRCCS Policlinico S. Donato, Milan, Italy.

Objective: High risk, inoperable patients with ascending aortic disease are increasingly managed with thoracic endovascular aortic repair (TEVAR). The aim of this study was to assess the available literature on TEVAR confined to the ascending aorta (aTEVAR), describing study and patient characteristics, procedural and stent graft details, and outcomes.

Data Sources: This was a systematic review and meta-analysis.

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Objectives: Thoracic/abdominal aortic aneurysms and aortic stenosis may be concomitant diseases requiring both transcatheter aortic valve implantation (TAVI) and endovascular aneurysm repair (T/EVAR) in high-risk patients for surgical approaches, but temporal management is not clearly defined yet. The aim of the study was to analyse outcomes of simultaneous versus staged TAVI and T/EVAR.

Methods: Retrospective observational multicentre study was performed on patients requiring TAVI and T/EVAR from 2016 to 2022.

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Objectives: To evaluate gender-related outcomes during endovascular treatment of thoracic and thoraco-abdominal aortic diseases (TEVAR).

Methods: Multicentre, retrospective, observational cohort study. All TEVARs between January 2005 and April 2023 were identified.

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Objectives: To evaluate the results of isolated left subclavian artery in-situ fenestration (ISF) during 'zone 2' thoracic endovascular aortic repair (TEVAR) using a new adjustable needle puncturing device system.

Methods: It is a multicentre, retrospective, physician-initiated cohort study of patients treated from 28 July 2021 to 3 April 2024. Inclusion criteria were isolate left subclavian artery revascularization for elective or urgent/emergent 'zone 2' TEVAR.

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Clinical cases referring to the EACTS/STS Guidelines for diagnosing and treating acute and chronic syndromes of the aortic organ aim to assist physicians in selecting the best management strategies for individual patients with a given condition. These expert opinions consider the impact on patient outcomes as well as the risk-benefit ratio of different diagnostic or therapeutic methods. These cases serve as a vital tool to aid physicians in making decisions in their daily practice.

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Purpose: Endovascular aortic repair (EVAR) is currently expanding its feasibility thanks to design innovations, but hostile proximal necks and narrow iliac arteries are still a constraint, as expressed by the Instructions for Use (IFU) of most devices. Our aim is to report the preliminary results of the E-Tegra endograft in infrarenal abdominal aortic aneurysms (AAAs) performed in 15 high-volume centers.

Materials And Methods: The e-Tegra Italian endoGraft REgistry (TIGRE) is a prospectively maintained database of consecutive EVAR with the E-Tegra stent-graft across 15 participating centers between March 2021 and March 2023.

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Objectives: To analyze how the experience of the surgical team went to impact the outcomes after open surgical repair (OSR) of intact abdominal aortic aneurysms (AAAs).

Methods: This is a single-center, observational cohort study with retrospective analysis of all OR for intact AAA performed between 1 January 2010 and 31 December 2022. The primary outcome was survival at 30 days and in follow-up, and a composite outcome of mortality and major complication.

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Article Synopsis
  • * A systematic review analyzed 27 studies involving 1,498 BTAI patients treated with TEVAR, finding an overall mortality rate of 12% and long-term survival rates of around 90% at 1 year post-treatment.
  • * The findings suggest that while BTAI carries significant risks, TEVAR offers a safe and effective management option with a low likelihood of needing additional procedures, emphasizing the importance of timely diagnosis and transfer to trauma centers.
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Article Synopsis
  • Advanced endovascular techniques like fenestrated stent grafts offer minimally invasive options for treating complex abdominal aortic aneurysms, but have limitations with thoracoabdominal cases due to anatomical challenges.
  • Branched endovascular aneurysm repair, specifically the Zenith t-Branch endograft, has emerged as a practical solution, providing an off-the-shelf option particularly useful in urgent situations where custom grafts may take too long.
  • Although early results are promising, risks such as spinal cord ischemia and long-term durability issues need further evaluation, especially since most available data comes from high-volume centers that may present biases in reported outcomes.
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Introduction: Blunt thoracic aortic injury (BTAI) represents one of the most devastating scenarios of vascular trauma which warrants prompt recognition with expedited management. Clinical manifestations of BTAI may not be straightforward to detect and may be misdiagnosed. Therefore, diagnosis of BTAI requires a high index of suspicion based on the mechanism of injury along with urgent transfer to centers with appropriate expertise and facilities.

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Objective: This study aimed to compare two commercially available off the shelf branched endografts for thoraco-abdominal aortic aneurysm (TAAA) repair, namely the E-nside (Artivion) and Zenith t-Branch (Cook Medical) devices.

Methods: This multicentre retrospective study (2020 - 2023) included patients treated by branched endovascular aortic repair (BEVAR) for TAAA using the inner branched E-nside or the outer branched t-Branch. Endpoints were 30 day technical success and major adverse events (MAEs) as well as one year freedom from target vessel instability and main endograft instability.

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Background: Heparin-bonded expanded polytetrafluoroethylene (hb-ePTFE) synthetic grafts are an alternative to autologous vein grafts (AVG) for surgical bypass interventions in lower limb peripheral arterial disease (LLPAD). However, the clinical benefits of hb-ePTFE grafts have not been reviewed systematically for patients undergoing below-the-knee (BK) surgical bypass. This study aimed to meta-analyze available data on the utility of hb-ePTFE in patients undergoing BK surgical bypass.

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Article Synopsis
  • * Data was collected from 329 patients who underwent ABFB at 12 centers between 2016 and 2021, finding no major differences in demographics or complications between the two treatment groups.
  • * Results showed that while primary ABFB had a higher 5-year primary patency rate (88% vs 69% for post-EVT), secondary patency and limb salvage rates were similar for both groups, suggesting both approaches are safely effective.
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Background: To estimate the impact of anesthetic conduct, alone and in combination with the type of femoral access, on early results after endovascular aneurysm repair (EVAR).

Methods: A retrospective multicenter analysis on patients undergoing elective standard EVAR at four academic centers was performed. Patients undergoing the procedure through either local or general anesthesia were compared.

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EACTS/STS Guidelines for Diagnosing and Treating Acute and Chronic Syndromes of the Aortic Organ.

Ann Thorac Surg

July 2024

Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Duke University, Durham, North Carolina.

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Objectives: To analyze the incidence and predictive factors of postoperative acute kidney injury (AKI) after elective standard endovascular aortic repair (EVAR) in a large recent, multicenter cohort.

Materials And Methods: This is a multicenter, retrospective, financially unsupported physician-initiated observational cohort study. Between January 2018 and March 2021, only patients treated with elective standard EVAR for infrarenal non-infected abdominal aortic aneurysm were analyzed.

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Objectives: To evaluate the feasibility of thoracic endovascular aortic repair (TEVAR) using the Ankura™ device (Lifetech Scientific, Shenzhen, China) with left subclavian artery (LSA) in-situ fenestration (ISF) using an adjustable puncture device system.

Methods: It is a single center, retrospective, financially unsupported cohort study of TEVAR performed from 16 February 2007 to 10 January 2023. Inclusion criteria were isolate LSA revascularization for elective or urgent/emergent "zone 2" TEVAR, and the availability of the preoperative computed tomography angiography.

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Background: The aim of the present study was to assess early and long-term results of open surgical interventions for popliteal artery aneurysms (PAAs) with the use of heparin-bonded expanded polytetrafluorethylene (HePTFE) in a single center, retrospective, non-comparative cohort study.

Methods: A retrospective analysis of a prospectively maintained dataset, including 207 open interventions for PAAs between 2002 and 2022, was performed and 170 procedures carried on with the use of a HePTFE graft were found. Perioperative results were analyzed in terms of mortality, graft thrombosis and amputation rates.

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Objective: Major adverse cardiac events (MACEs) were common complications after endovascular aortic repair (EVAR) causing significant postoperative morbidity and mortality. The aim of the study was to evaluate the cardiac risk after elective EVAR for uncomplicated noninfected infrarenal abdominal aortic aneurysm in a large multicenter cohort.

Methods: This is a multicenter, retrospective, financially unsupported physician-initiated observational cohort study conducted by four academic tertiary referral hospitals from January 2018 to March 2021.

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Article Synopsis
  • This study looks at how a special type of vein, called cryopreserved saphenous vein (CSV), works in surgeries to improve blood flow in legs that might need amputation.
  • Researchers checked the results from 95 patients over several years to see how well the surgeries helped avoid major problems like dying or needing a leg amputation.
  • They found that using CSV can really help in saving legs by keeping blood flowing, and certain factors, like how the surgery is done, can affect how well it works.
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Article Synopsis
  • - Pediatric major arterial vascular injuries are rare, making up less than 2% of all vascular trauma cases, and they are not well-documented compared to adult injuries.
  • - Open surgery is typically used for treatment, but there are no established guidelines for the best practices in strategy, repair, or postoperative care for these cases.
  • - The article discusses three specific cases and reviews existing literature to highlight important considerations in managing pediatric arterial injuries.
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Objectives: The aim of this study was to evaluate the incidence and outcomes of ischaemic organ complications after thoracic endovascular aortic repair (TEVAR).

Methods: This is a multicentre, retrospective, observational cohort study. We analysed data from patients treated with TEVAR between 22 June 2001 and 10 December 2022.

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