Power law in COVID-19 cases in China.

The novel coronavirus (COVID-19) was first identified in China in December 2019. Within a short period of time, the infectious disease has spread far and wide. This study focuses on the distribution of COVID-19 confirmed cases in China-the original epicentre of the outbreak.

Hematopoiesis with Obesity and Exercise: Role of the Bone Marrow Niche.

Hematopoietic stem and progenitor cells (HSPC), the most primitive cells of the hematopoietic system responsible for maintaining all mature blood cells, display the hallmark characteristics of self-renewal and multi-potent differentiation into mature cell lineages. HSPC activity is directed by the bone marrow niche, a complex environment composed of heterogeneous cell populations that regulate HSPC function through the secretion of a wide array of cytokines and growth factors. Diet induced obesity results in a dramatic remodeling of the bone marrow niche, skewing HSPC function resulting in a compromised immune system.

EMSA Analysis of DNA Binding By Rgg Proteins.

In bacteria, interaction of various proteins with DNA is essential for the regulation of specific target gene expression. Electrophoretic mobility shift assay (EMSA) is an approach allowing for the visualization of these protein-DNA interactions. Rgg proteins comprise a family of transcriptional regulators widespread among the Firmicutes.

Health profile of aging family caregivers supporting adults with intellectual and developmental disabilities at home.

The health status of 206 female caregivers supporting adults with intellectual and developmental disabilities at home was investigated using objective (i.e., presence of chronic health conditions and activity limitations) and subjective (i.

Principles of drug transfer into breast milk and drug disposition in the nursing infant.

There are numerous factors to consider when assessing the safety of drugs in lactating women. Drug properties facilitating transfer into milk as well as the pharmacokinetic properties of the drug in the mother and infant must be evaluated. Drug properties which promote low milk concentrations are: large volume of distribution, high protein binding, low lipid solubility, ionization at physiologic pH and large molecular weight.

Characterization of the effect of introgressed segments of chromosome 7 and 10 from Lycopersion chmielewskii on tomato soluble solids, pH, and yield.

Three chromosomal segments from the wild tomato L. chmielewskii have been introgressed into the L. esculentum genome.

The oxytocic effect of xylazine on the canine uterus.

The effect of xylazine on intrauterine pressure was compared to that of prostaglandin and oxytocin in seven diestrual bitches. Microtipped pressure transducers were surgically implanted in the uteri of four bitches at 30 d diestrus and in three bitches at 60 d diestrus. Uterine contractile force was measured in the awake bitches on Day 1 and Day 2 following implantation.

A closed-loop theory of motor learning.

Following a discussion of the meaning of the term "skills" and a review of historical influences on their learning, a closed-loop theory for learning simple movements is presented. Empirical generalizations from the literature are stated, and the theory is used to explain them. The generalizations are of 2 classes: learning through the application of knowledge of results, and the effects of withdrawing knowledge of results.