The effects of chicken hydrolyzed proteins in extruded diets on plasma and fecal metabolic profiles in adult dogs.

Research has shown various hydrolyzed proteins possessed beneficial physiological functions; however, the mechanism of how hydrolysates influence metabolism is unclear. Therefore, the current study aimed to examine the effects of different sources of protein hydrolysates, being the main dietary protein source in extruded diets, on metabolism in healthy adult dogs. Three complete and balanced extruded canine diets were formulated: control chicken meal diet (CONd), chicken liver and heart hydrolysate diet (CLHd), mechanically separated chicken hydrolysate diet (CHd).

Strained two-dimensional tungsten diselenide for mechanically tunable exciton transport.

Tightly bound electron-hole pairs (excitons) hosted in atomically-thin semiconductors have emerged as prospective elements in optoelectronic devices for ultrafast and secured information transfer. The controlled exciton transport in such excitonic devices requires manipulating potential energy gradient of charge-neutral excitons, while electrical gating or nanoscale straining have shown limited efficiency of exciton transport at room temperature. Here, we report strain gradient induced exciton transport in monolayer tungsten diselenide (WSe) across microns at room temperature via steady-state pump-probe measurement.

Examining social attention as a predictor of problem drinking behavior: A longitudinal study using eye-tracking.

Background: Researchers have long been interested in identifying objective markers for problem drinking susceptibility informed by the environments in which individuals drink. However, little is known of objective cognitive-behavioral indices relevant to the social contexts in which alcohol is typically consumed. Combining group-based alcohol administration, eye-tracking technology, and longitudinal follow-up over a 2-year span, the current study examined the role of social attention in predicting patterns of problem drinking over time.

Systematic review: differences in complete blood count component rhythms.

Study Objectives: The complete blood count (CBC) is one of the most commonly ordered blood tests with a large range of reference values that does not consider time of day for interpretation. Our objective was to systematically review this topic to report on peak and trough timing of CBC values.

Methods: A systematic search was performed for studies evaluating any component of the CBC with at least three collections over 24 hours.

Snaplage residue as a fiber source for finishing beef cattle under grazing: effects on residue characteristics, cattle behavior and performance, and carcass traits.

The snaplage residue presents itself as a potential alternative roughage source in finishing systems, owing to its high fiber concentration which aids in maintaining rumen health. Nevertheless, the performance of animals will hinge on both the allowance and the nutritive value it offers. This study aimed to evaluate different stocking rates of heifers grazing snaplage residue as an exclusive source of fiber on finishing phase performance.

Brd4 modulates metabolic endotoxemia-induced inflammation by regulating colonic macrophage infiltration in high-fat diet-fed mice.

High-fat diet (HFD) induces low-grade chronic inflammation, contributing to obesity and insulin resistance. However, the precise mechanisms triggering obesity-associated metabolic inflammation remain elusive. In this study, we identified epigenetic factor Brd4 as a key player in this process by regulating the expression of Ccr2/Ccr5 in colonic macrophage.

Top-down instructions influence the attentional weight on color and shape dimensions during bidimensional search.

Efficient searches are guided by target-distractor distinctiveness: the greater the distinctiveness, the faster the search. Previous research showed that when the target and distractors differ along both color and shape dimensions (i.e.

Microstructural characterization of a wheat-based food material using image analysis and pore network modeling during baking.

Microstructural properties of wheat-based food materials change during baking. These alterations affect the final product's mechanical properties, physical attributes, and consumer satisfaction. Image processing and pore network modeling were used to analyze the variations in a cookie's microstructural properties during baking.

Community health promotion and disaster recovery: a PhotoVoice project in Comerío, Puerto Rico.

Background: PhotoVoice - a series of workshops involving participatory photography and narrative-building - was employed in the rural town of Comerío, Puerto Rico (PR) to describe disaster recovery in a rural setting and foster policy dialogue.

Methods: Using PhotoVoice workshops and ethnographic observations, the project describes how women affiliated with a local community-based organization described the priorities for disaster recovery in visual images and narratives. We draw analytically upon theories of intersectionality and coloniality to describe socio-structural and community factors that shape community health in the context of ongoing disasters.

Nutritional composition, nitrogen-corrected true metabolizable energy, and standardized amino acid digestibility of palm kernel meal from several countries.

Extensive nutritional analyses were conducted for palm kernel meal (PKM) sourced from 5 countries. Two precision-fed rooster trials were conducted to evaluate the nitrogen-corrected true metabolizable energy (TME) and standardized amino acid (AA) digestibility of 10 PKM samples (PKM 1 to 10). The TME was determined using conventional Single Comb White Leghorn roosters, and standardized AA digestibility was determined using cecectomized roosters.

alkyl quinolone response is dampened by .

Unlabelled: The bacterium is an opportunistic pathogen that can cause lung, skin, wound, joint, urinary tract, and eye infections. While is known to exhibit a robust competitive response toward other bacterial species, this bacterium is frequently identified in polymicrobial infections where multiple species survive. For example, in prosthetic joint infections, can be identified along with other pathogenic bacteria including , , and .

Wild Tibetan Macaques Use a Route-Based Mental Map to Navigate in Large-Scale Space.

Many animals face significant challenges in locating and acquiring resources that are unevenly distributed in space and time. In the case of nonhuman primates, it remains unclear how individuals remember goal locations and whether they navigate using a route-based or a coordinate-based mental representation when moving between out-of-sight feeding and resting sites (i.e.

A novel herpesvirus in blue penguins putatively associated with myocardial degeneration and necrosis.

We identified a novel herpesvirus in 2 deceased captive blue penguins (). Moderate-to-severe myocardiocyte atrophy and necrosis, and eosinophilic intranuclear inclusion bodies (INIBs), were seen in myocardiocytes in one bird; reticuloendothelial (RE) cell INIBs and multifocal RE cell necrosis were seen in both birds. The histologic findings were suggestive of viral infection.

Feed additives for methane mitigation: A guideline to uncover the mode of action of antimethanogenic feed additives for ruminants.

This publication aims to provide guidelines of the knowledge required and the potential research to be conducted in order to understand the mode of action of antimethanogenic feed additives (AMFA). In the first part of the paper, we classify AMFA into 4 categories according to their mode of action: (1) lowering dihydrogen (H) production; (2) inhibiting methanogens; (3) promoting alternative H-incorporating pathways; and (4) oxidizing methane (CH). The second part of the paper presents questions that guide the research to identify the mode of action of an AMFA on the rumen CH production from 5 different perspectives: (1) microbiology; (2) cell and molecular biochemistry; (3) microbial ecology; (4) animal metabolism; and (5) cross-cutting aspects.

Alternating Cellular Functions by Optogenetic Control of Organelles.

Organelles play essential roles in cellular homeostasis and various cellular functions in eukaryotic cells. The current experimental strategy to modulate organelle functions is limited due to the dynamic nature and subcellular distribution of organelles in live cells. Optogenetics utilizes photoactivatable proteins to enable dynamic control of molecular activities through visible light.

Kinetic Analysis of Cyclization by the Substrate-Tolerant Lanthipeptide Synthetase ProcM.

Lanthipeptides are ribosomally synthesized and post-translationally modified peptides (RiPPs) characterized by the presence of thioether cross-links called lanthionine and methyllanthionine, formed by dehydration of Ser/Thr residues and Michael-type addition of Cys side chains onto the resulting dehydroamino acids. Class II lanthipeptide synthetases are bifunctional enzymes responsible for both steps, thus generating macrocyclic natural products. ProcM is part of a group of class II lanthipeptide synthetases that are known for their remarkable substrate tolerance, having large numbers of natural substrates with highly diverse peptide sequences.

A sparse latent class model incorporating response times.

Diagnostic models (DM) have been widely used to classify respondents' latent attributes in cognitive and non-cognitive assessments. The integration of response times (RTs) with DM presents additional evidence to understand respondents' problem-solving behaviours. While recent research has explored using sparse latent class models (SLCM) to infer the latent structure of items based on item responses, the incorporation of RT data within these models remains underexplored.

High-Performance Boiling Surfaces Enabled by an Electrode-Transpose All-Electrochemical Strategy.

High-performance boiling surfaces are in great demand for efficient cooling of high-heat-flux devices. Although various micro-/nano-structured surfaces have been engineered toward higher surface wettability and wickability for enhanced boiling, the design and fabrication of surface structures for realizing both high critical heat flux (CHF) and high heat transfer coefficient (HTC) remain a key challenge. Here, a novel "electrode-transpose" all-electrochemical strategy is proposed to create superhydrophilic microporous surfaces with higher dendrites and larger pores by simply adding an electrochemical etching step prior to the multiple electrochemical deposition steps.

Surface-enhanced Raman spectroscopy: a half-century historical perspective.

Surface-enhanced Raman spectroscopy (SERS) has evolved significantly over fifty years into a powerful analytical technique. This review aims to achieve five main goals. (1) Providing a comprehensive history of SERS's discovery, its experimental and theoretical foundations, its connections to advances in nanoscience and plasmonics, and highlighting collective contributions of key pioneers.

Area under the ROC Curve has the most consistent evaluation for binary classification.

The proper use of model evaluation metrics is important for model evaluation and model selection in binary classification tasks. This study investigates how consistent different metrics are at evaluating models across data of different prevalence while the relationships between different variables and the sample size are kept constant. Analyzing 156 data scenarios, 18 model evaluation metrics and five commonly used machine learning models as well as a naive random guess model, I find that evaluation metrics that are less influenced by prevalence offer more consistent evaluation of individual models and more consistent ranking of a set of models.

Long non-coding RNA fine-tunes bone homeostasis and repair by orchestrating cellular crosstalk and β-catenin-OPG/Jagged1 pathway.

The IncRNA was initially believed to be dispensable for physiology due to the lack of observable phenotypes in knockout (KO) mice. However, our study challenges this conclusion. We found that both KO and conditional KO mice in the osteoblast lineage exhibit significant osteoporosis.

Time-calibrated phylogeny of neotropical freshwater fishes.

Neotropical Freshwater Fish (NFF) fauna exhibits the greatest phenotypic disparity and species richness among all continental aquatic vertebrate faunas, with more than 6,345 species distributed across the mostly tropical regions of Central and South America. The last two decades have seen a proliferation of molecular phylogenies, often at the species level, covering almost all 875 valid NFF genera. This study presents the most comprehensive genome-wide, time-calibrated phylogenetic hypothesis of NFF species to date, based on DNA sequences generated over decades through the collaborative efforts of the multinational ichthyological research community.

A Critical Perspective on Photothermal De-Icing.

To tackle the formidable challenges posed by extreme cold weather events, significant advancements have been made in developing functional surfaces capable of efficiently removing accreted ice. Nevertheless, many of these surfaces still require external energy input, such as electrical power, which raises concerns regarding their alignment with global sustainability goals. Over the past decade, increasing attention has been directed toward photothermal surface designs that harness solar energy-a resource available on Earth in quantities exceeding the total reserves of coal and oil combined.

EPA/DHA but Not ALA Reduces Visceral Adiposity and Adipocyte Size in High Fat Diet-Induced Obese Delta-6 Desaturase Knockout Mice.

The objective of this omega-3 feeding study was to elucidate the independent effects of α-linolenic acid (ALA) versus eicosapentaenoic (EPA)/docosahexaenoic acid (DHA) on visceral adiposity and inflammatory signaling in diet-induced obese delta-6 desaturase (Fads2) knockout (KO) mice. Male wildtype (WT) and Fads2 KO mice were fed a high-fat diet (45% kcal from fat) containing either lard (no omega-3s), flaxseed (ALA), or menhaden (EPA/DHA) for 21 weeks. Epididymal white adipose tissue (eWAT) was analyzed for changes in tissue weight, adipocyte size, triacylglycerol (TAG) and fatty acid content, and inflammatory markers.